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Inovarion
Inovarion is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Research & Development
- DNA/Protein analysis Analyze DNA and proteins for allergens, pathogens and species identification.
Antibodies
- Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
Bioimaging
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
- Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
- In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
- Single Molecule Localization Microscopy Enable structural resolution of biological samples at the nanometer range using light in the visible spectrum.
Biomarkers
- Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Show all 12 in Biomarkers
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Platelet Function Testing Evaluate complete platelet function in vivo or in vitro.
- Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
- TUNEL Assay Detect in situ DNA fragmentation.
Show all 99 services
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Construction Create new recombinant cell lines to exact specifications.
Show all 11 in Cell Culture and Characterization
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Karyotyping Evaluate the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
- Microsatellite Instability Analysis Compare allelic profiles and detect genomic instability.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Chemical and Compound Analysis
- Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
- Denaturing High Performance Liquid Chromatography Separate mixtures of denatured and reannealed oligos to identify single nucleotide substitutions, deletions and insertions.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Show all 10 in Chemical and Compound Analysis
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
- Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- Biostatistical Design Use statistics to ensure appropriate pre-clinical and clinical study design.
- In Silico Protein Modification Analysis Use computational methods to predict the behavior of modified proteins.
- In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.
- Microsatellite Analysis for Normal Tumor Instability (MANTIS) Classify samples by MSI status utilizing NGS data.
Disease Models
- Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
DNA & RNA
- Digital Polymerase Chain Reaction Obtain improved absolute target quantification and rare allele detection compared to conventional qPCR.
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
Show all 9 in DNA & RNA
- Restriction Fragment Length Polymorphism Identification Uses gel electrophoresis to identify differences in restriction fragment lengths produced by enzymatic digestion of DNA.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
- RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
Human Biological Samples
- Human 3D cultures Provision of 3D culture of Human Primary Cells
- Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
In Vitro ADME
- Cell Fractionation Isolate organelles and subcellular components.
- Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
In Vitro Assays
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Microbiology Study microbes and their role in human health.
Show all 8 in In Vitro Assays
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
- Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
In Vitro Pharmacology
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
Medical Communications
- Medical Publications Make clear and accurate presentations of scientific and technical data.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
New Product Development
- Vitamins Analysis Analyze vitamins in foods and dietary supplements either by HPLC or titration.
Protein Sciences
- Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
- Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Show all 14 in Protein Sciences
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- Peptide Array Use biologically active synthetic peptides arranged in a high density format to assess protein interaction.
- Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
REACH Services
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Real World Evidence & Data
- Secondary Real World Evidence Analyze clinical trial data.
Scientific Data Services
- Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
Testing Services
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
- Website
- www.inovarion.com
Where it operates
Sites by country, with the cities in each.
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France 1 site
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