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Nikon Instruments Inc.
Nikon Instruments Inc. is listed as a large business research supplier in the Scientist.com network, with 3 sites in 1 country.
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Sites
3
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Antibodies
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
Bioimaging
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
- Photoactivated Localization Microscopy (PALM) Visualize and localize individual endogenous fluorophores.
- Single Molecule Localization Microscopy Enable structural resolution of biological samples at the nanometer range using light in the visible spectrum.
- Super Resolution Microscopy Utilize fluorescence microscopy and super-resolution techniques including STED, SIM, SMLM, and/or STORM to directly observe living subcellular structures and activities.
Biomarkers
- Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
- HCS Assay Development Requesting services related to HCS assay development.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Show all 7 in Biomarkers
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
Show all 40 services
Cell Culture and Characterization
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Multiplex Immunofluorescence Multiplex immunofluorescence (mIF) is an advanced tissue-imaging technique that allows researchers to simultaneously detect and visualize multiple protein markers within a single tissue section
Chemical and Compound Analysis
- Stochastic Optical Reconstruction Microscopy (STORM) Visualize and localize individual fluorescent molecules.
- Total Internal Reflection Fluorescence Microscopy Visualize single molecule fluorescence at a surface to produce high quality images with low background.
DNA & RNA
- HCR™ RNA-FISH Detect and visualize RNA expression in situ
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
- RNAscope In Situ Assays Profile single-cell gene expression in situ.
- Spatial Transcriptomics Determine the sub-cellular localization of mRNA molecules. Use this to identify cellular heterogeneity in tissues, tumors, immune cells and the subcellular distribution of transcripts.
Human Biological Samples
- Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Assay Development Construct or create new assays or modify existing ones.
- BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Show all 12 in In Vitro Assays
- Cell Painting Cell painting is multiplexed image-based assay used to investigate subtle changes in cellular homeostasis
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Other Specialty Toxicology
- Phototoxicity Determine whether drug treatment causes light-activated toxic effects.
Protein Sciences
- Intracellular Trafficking Intracellular Trafficking is when cells transport molecules and proteins from one location to another within the cell.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Scientific Data Services
- Automated Image Analysis Automated Image Analysis
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
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