CrystalsFirst

CrystalsFirst is listed as a small business research supplier in the Scientist.com network, with 5 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 5

Countries 1

Type of company: Small business

Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.

Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
Natural Product Libraries Find microbial, botanical and marine sources of natural products.
Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
Structural Chemistry Examine the relationship between protein structure and function.

Show all 7 in Chemical and Compound Analysis 1 more

Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Compound Purchase Buy compounds, building blocks or compound libraries.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Show all 31 services 17 more

Chemoinformatics Consulting The use of computer and informational techniques applied to a range of problems in the field of chemistry.
Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.

Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Protein/Enzyme Targets For requesting Protein/Enzyme Targets
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
Protein Binding Determine drug-protein binding interactions
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.

Show all 9 in Protein Sciences 3 more

Protein Purification Isolate native or recombinant proteins from a sample.
Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.

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