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Imagen Therapeutics

Imagen Therapeutics is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: New startup

Biomarkers

  • Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
  • Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • Cytogenetics Examine the structure and function of the cell, especially chromosomes.
Show all 14 in Biomarkers 8 more
  • Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
  • Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
  • Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
  • Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.

Cell Culture and Characterization

  • 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Cell Culture Culture primary or immortalized cell lines.
  • Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
  • Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
  • Microsatellite Instability Analysis Compare allelic profiles and detect genomic instability.
Show all 7 in Cell Culture and Characterization 1 more
  • Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Show all 48 services 36 more

Clinical Consulting

  • Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

DNA & RNA

  • Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
  • RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
  • Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
  • Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.

Human Biological Samples

  • Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
  • Custom PDX models For requesting Custom PDX models
  • Existing PDX models For requesting Existing PDX models
  • HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
  • Human 3D cultures Provision of 3D culture of Human Primary Cells
  • Human Cell Lysates For requesting human Cell lysates.
Show all 8 in Human Biological Samples 2 more
  • Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc
  • Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...

In Vitro Assays

  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • Assay Development Construct or create new assays or modify existing ones.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
Show all 10 in In Vitro Assays 4 more
  • High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
  • In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
  • Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

In Vitro Pharmacology

  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.
  • Target Identification Identify the target(s) of a biologically active substance.

In Vitro Toxicology

  • ADCC and CDC Assay Services Measure toxicity of antibodies.

Oncology Models

  • Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Daresbury 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Professional associations
AAPS
Website
www.imagentherapeutics.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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