HelEx

HelEx is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: New startup

Cell Culture and Characterization

Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.

Data Science/Bioinformatics

In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.

Disease Models

Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
Disease Simulation Modeling Disease Simulation Modeling
Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.

DNA & RNA

CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
DTG-Seq™ Evaluate the efficiency and distribution of CRISPR mutations at on-target sites.
Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.

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siRNA Synthesis Produce high quality siRNAs for gene silencing studies.

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In Vitro Pharmacology

In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Excitotoxicity Models Use in vitro models to measure therapeutic endpoints associated with excitotoxic pathology.
In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
In Vitro Oncology Models Use cell-based and biochemical models of cancer.

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Target Identification Identify the target(s) of a biologically active substance.

Safety Pharmacology

Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.

Testing Services

In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.

Other services

proxy-CRISPR Gain access to previously unreachable areas of the genome via proxy-CRISPR, a proximal CRISPR targeting method that restores FnCas9 nuclease activity.

Website: www.helex.bio

India Hyderabad 2 sites

Woman-owned

US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.

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