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INSIGHT BIOSOLUTIONS

INSIGHT BIOSOLUTIONS is listed as a new startup research supplier in the Scientist.com network, with 3 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 3

Countries 1

Type of company: New startup

Cell Culture and Characterization

Explant Culture Culture cells obtained from a part or parts of an in vivo structure.

Chemical and Compound Analysis

Structural Chemistry Examine the relationship between protein structure and function.

Data Science/Bioinformatics

Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
In Silico ADME-PK Consultation Consult with experts for ADME-PK data analysis or predictive modelling design in different in vivo or in vitro states.
In Silico ADME-PK Predictions Use computer software to simulate in vivo physiological conditions of animals or humans to predict ADME-PK properties.
In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
In Silico Pro-drug Predictions Use computer simulation to assess pro-drug absorption and conversion to predict pharmacokinetic properties.
In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.

Discovery Chemistry

Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.

Show all 8 in Discovery Chemistry 2 more

QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Show all 43 services 29 more

Drug Development

Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.

General in vivo Toxicology

Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.

In Vitro ADME

Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.

In Vitro Assays

In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Human Cell Assays Request in vitro human cells for assays

In Vitro Pharmacology

In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
In Vitro Excitotoxicity Models Use in vitro models to measure therapeutic endpoints associated with excitotoxic pathology.
In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
Target Identification Identify the target(s) of a biologically active substance.
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation
Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.

Model Development

In Silico PK-PD Modeling Quantitative modeling and simulations correlation of pharmacokinetic and pharmacodynamic endpoints in support of preclinical and clinical development.

REACH Services

OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...
OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.

Scientific Data Services

Data and Text Mining Derive structured data from free text in order to become accessible for data-mining algorithms.
Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
Software Tools Software tool for statistical analysis, data mining, genome annotation or NGS data analysis.
Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.

Testing Services

In Vitro Oral Care Product Testing Perform in vitro oral care product testing of dental products to evaluate safety and performance, including assessment for cleaning, brushing, whitening, stain removal, erosion, abrasivity and sensitivity.
In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.
OECD 442D: ARE-Nrf2 Luciferase Test An in vitro test method (KeratinoSensTM and/or LuSens) that models the second key event in the Adverse Outcome Pathway for Dermal Sensitization.

Website: www.insight-biosolutions.fr

France RENNES 3 sites

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