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PreciBio

PreciBio is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

Bioimaging

Fluorescence-Lifetime Imaging Microscopy (FLIM) Use FLIM to produce an image based on the differences in the excited state decay rate from a fluorescent sample.
Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Scanning Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.

Biomarkers

Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
Biomarker Screening Biomarker testing analyzes tissue, blood, or fluid samples to identify specific genes, proteins, or molecules that indicate disease, particularly cancer.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.

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Complete Blood Count Set of medical laboratory tests that provide information about the cells in blood.
Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Digital Biomarkers Objective, quantifiable physiological and behavioral data that are collected and measured by means of digital devices such as portables, wearables, implantables, or digestibles.
Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Human Primary Cell Isolation Isolate primary cells from various human tissues.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Lipid Peroxidation Assay Use in vitro or in vivo assays to evaluate the effects of oxidative stress on lipid structure and function.
Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.

Cell Culture and Characterization

3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
Cell Culture Culture primary or immortalized cell lines.
Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.

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Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
H & E Services For requesting services related to H&E Services
Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.

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Chemical and Compound Analysis

Atomic Force Microscopy Use atomic force microscopy to reveal information about the atomic topography and mechanical properties of a sample.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.

Chemistry, Manufacturing and Controls (CMC)

Subcellular Fraction Test System Obtain human, minipig, mouse, or rat dermal microsomes as in-stock standard test systems for the development of safer topical and transdermal products.

Discovery Chemistry

Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...

Disease Models

Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
Microdialysis Models Measure the effect of drug candidates on neurotransmission in rat or mouse models.

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Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.

DNA & RNA

Amplicon - HLA Typing Use an amplicon sequencing method to identify allelic variation within the HLA genes.
DNA Extraction Extract DNA from an original source.
Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.

Human Biological Samples

Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
BronchoAlveolar Lavage (BAL) Acquire fresh/frozen normal bronchial lavage based on patient demographics and history.
Cell Line and Cellular Services Promotion for Cells and Cell lines
Custom FFPE cell line blocks Custom IHC compatible FFPE cell line blocks and sections
Ex Vivo Skin Explants Aquire Ex vivo skin explants
HBS Alzheimer's Acquire fresh, frozen, or fixed Alzheimer's tissues or other related Alzheimer's HBS.

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HBS Amyotrophic Lateral Sclerosis (ALS) For requesting HBS Amyotrophic Lateral Sclerosis (ALS).
HBS Asthma For requesting HBS Asthma.
HBS Autoimmune Diseases For requesting Autoimmune Diseases HBS.
HBS Bacterial Infections Provision of HBS Bacterial Infections samples
HBS Cardiovascular Disease Request tissue samples and Bio-specimen samples from patients with Cardiovascular Disease
HBS Chronic Obstructive Pulmonary Disease (COPD) Acquire fresh, frozen, or fixed COPD tissue or for requesting other COPD human biospecimen samples.
HBS Diabetes For requesting HBS Diabetes.
HBS Genetic Diseases For requesting Genetic Diseases HBS
HBS Healthy/Controls For requesting HBS Healthy/Controls
HBS HepB positive For requesting HBS HepB positive.
HBS HepC positive For requesting HBS HepC positive
HBS HIV positive For requesting HBS HIV positive
HBS Huntington's For requesting HBS Huntington's.
HBS Kidney Disease Request samples from patients with Kidney Disease
HBS Leukemia For requesting HBS Leukemia
HBS Liver Disease Request samples from patients with Liver Disease.
HBS NASH For requesting HBS NASH
HBS Neurological Diseases For requesting Neurological Diseases HBS
HBS NSCLC For requesting HBS NSCLC
HBS Oncology For requesting Human biospecimens from Oncology indications
HBS Parkinson's For requesting HBS Parkinson's
HBS Viral Infections For requesting Viral Infection HBS
HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
Human 3D cultures Provision of 3D culture of Human Primary Cells
Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
Human Amniotic Fluid Acquire fresh/frozen normal amniotic fluid based on patient demographics and history.
Human Aqueous Humor Acquire fresh/frozen normal aqueous humor based on patient demographics and history.
Human Ascites Acquire fresh/frozen Ascites based on patient demographics, disease stage, treatment and history.
Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
Human Biopsy Cell Models Request human biopsy cell models.
Human Blood Acquire fresh/frozen human blood based on patient demographics, disease stage, history and treatment.
Human Blood by-products For requesting Human Blood By-products
Human Bone Marrow Aspirates Acquire fresh/frozen Bone Marrow mononuclear cells based on patient demographics, disease stage, treatment and history.
Human Bone Marrow Cells Acquire fresh, frozen, or fixed normal bone marrow based on patient demographics and history.
Human Breast Milk Acquire fresh/frozen normal breast milk based on patient demographics and history.
Human Buffy Coats Acquire fresh/frozen Buffy Coats based on patient demographics, disease stage, treatment and history.
Human Cell Lysates For requesting human Cell lysates.
Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc
Human Cerebral Spinal Fluid (CSF) Acquire fresh/frozen normal cerebrospinal fluid based on patient demographics and history.
Human DNA Acquire human DNA.
Human DNA & RNA Acquire fresh/frozen Human DNA & RNA based on patient demographics, disease stage, treatment and history
Human Endothelial Cells Endothelial cells are specialized epithelial cells that form a single layer lining the inner surface of all blood vessels and lymphatic vessels
Human Epithelial Cells Human epithelial cells are the most abundant cell type in the body and form the outer layer of skin and line various internal organs, including the digestive and respiratory tracts.
Human Fecal Matter Acquire fresh/frozen normal feces based on patient demographics and history.
Human Fibroblasts Human Fibroblasts play a vital role in forming connective tissue
Human Fixed Tissue Acquire Human fixed tissue based on patient demographics, disease stage, history and treatment.
Human Fresh Tissue For requesting fresh human tissue
Human Frozen Tissue For requesting frozen human tissue.
Human HSC's For requesting human sourced hematopoetic stem cells
Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
Human iPSC's For requesting human sourced induced pluripotent stem cells.
Human Leukopaks Obtain enriched leukapheresis-derived products from normal peripheral blood.
Human Melanocytes Human Melanocytes are pigment-producing cells primarily found in the skin, hair follicles, and eyes
Human Microsomes Acquire microsomes derived from the endoplasmic reticulum of hepatic cells
Human MSC's For requesting human sourced mesenchymal stem cells.
Human Myoblasts Human Myoblasts are a type of immature white blood cell that forms in the bone marrow
Human Nasal Fluid Acquire fresh/frozen normal nasal fluid based on patient demographics and history.
Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...
Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
Human Plasma Acquire fresh/frozen human plasma
Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
Human Red Blood Cells Acquire fresh/frozen normal red blood cells based on patient demographics and history.
Human RNA Acquire fresh/frozen Human RNA based on patient demographics, disease stage, treatment and history.
Human Saliva Acquire fresh/frozen normal saliva based on patient demographics and history.
Human Semen Acquire fresh/frozen normal semen based on patient demographics and history.
Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.
Human Sputum Acquire fresh/frozen normal sputum based on patient demographics and history.
Human Synovial Fluid Acquire fresh/frozen normal synovial fluid based on patient demographics and history.
Human Tears Acquire fresh/frozen Tears based on patient demographics, disease stage, treatment and history.
Human TMA For requesting Human Tissue MicroArrays
Human Umbilical Cord Blood For requesting Human Umbilical Cord Blood.
Human Urine Acquire fresh/frozen normal urine based on patient demographics and history.
Human Vitreous Humor Acquire fresh/frozen normal vitreous humor based on patient demographics and history.
Human Whole Blood Acquire fresh/frozen normal whole blood based on patient demographics and history.
Human Whole Organs Procure non-transplantable whole human organs or tissues, healthy or diseased, for medical research and development.
Liquid Biopsy Test and detect either circulating tumor cell-associated biomarkers or circulating tumor DNA.
Tumor Cells Acquire tumor cells (either human or animal)

In Vitro ADME

Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
Cell Fractionation Isolate organelles and subcellular components.
Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).

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CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
In Vitro ADME in Vitro ADME services
Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
Multidrug Resistance Identify potential causes of drug-drug interactions.
Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.

In Vitro Assays

3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
Apoptotic Cell Staining Detect apoptotic cells in culture.
Assay Development Construct or create new assays or modify existing ones.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
Glucose Release Assay Determine free glucose levels in biological samples.

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Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.
Human Custom TMA For requesting Human Custom Microarray Services
In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
Von Willebrand Factor Analysis Detect and classify the Von Willebrand disease sub-type.

In Vitro Pharmacology

Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
In Vitro Bone Models Measure osteoclast activity and bone formation in human or rat osteoclasts.
In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.

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In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vitro Oncology Models Use cell-based and biochemical models of cancer.
Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.
Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation
Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.

In Vivo Pharmacokinetics

Cardiac Safety Assessment Assess cardiotoxicity using microelectrode assay technology.
Integrated In Vivo Services Package Process an entire In Vivo Project including: Dose Formulation, PK Screening, ADME-Profiling, Toxicology, Safety Pharmacology, DART, IND Filing from our bundle of suppliers.
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.

Lab Supplies, Facilities, and Equipment

Biobanking Store and track biological samples.

Model Development

3D Blood-Brain Barrier Model Use an in vitro 3D blood–brain barrier model for real-time visualization of cellular and barrier functions.

Nanotechnology

Metal/Metal Oxide Nanoparticle Synthesis Use nanoparticles for drug and gene delivery, imaging, analyte detection, labeling and DNA structure determination.
Nanoparticle Conjugation and Functionalization Modify biomolecules to enhance structure and function.
Nanoparticle Synthesis Create nano-level structures with unique features.

Non-Human Biospecimen

Dog / Canine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Monkey / Non-Human Primate / NHP Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Monkey / Non-Human Primate / NHP Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Monkey / Non-Human Primate / NHP Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Mouse Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.

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Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Rabbit Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Rabbit Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Rabbit Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Rat Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Rat Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Rat Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.

Protein Sciences

Cytokines Find recombinant cytokines or cytokine assays.
Protein Binding Determine drug-protein binding interactions

Testing Services

In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.

Website: preci.bio

Ukraine Bila Tserkva, Kyiv 2 sites

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