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Aminoverse B.V.

Aminoverse B.V. is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

Antibodies

AlphaLISA Quantification of analytes with high sensitivity, wider dynamic range and no wash steps involved.
Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
Recombinant Antibody Production Request services related to antibody production services.
Yeast Display Discover or optimize eukaryotic proteins and antibodies that contain post translational modifications

Bioimaging

Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
HCS Assay Development Requesting services related to HCS assay development.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.

Cell Culture and Characterization

Bacterial Cell Culture Culture and Grow bacterial cells.
Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
Yeast Cell Culture Grow yeast strains or species.

Show all 138 services 125 more

Chemical and Compound Analysis

Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Ion Exchange Chromatography Separate and detect analytes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Process Residual Impurities Detection Measure trace levels of impurities.

Show all 10 in Chemical and Compound Analysis 4 more

Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Structural Chemistry Examine the relationship between protein structure and function.

Chemical and Compound Testing

Residual Lipase and Esterase Activity Testing Quantify residual host cell lipase and esterase activity in biologic drug substances, formulations and process samples using sensitive enzymatic activity assays, enabling prediction and control of polysorbate...
Residual Protease Activity Testing Quantify residual host cell protease activity in biologic drug substances, formulations and process samples using sensitive enzymatic activity assays, enabling prediction and control of protein fragmentation, clipping...

Chemistry, Manufacturing and Controls (CMC)

Analytical Development and Validation Request services related to Analytical Development and Validation
API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
Lyophilization Lyophilization, also known as freeze-drying, is a dehydration process typically used to preserve perishable materials

Show all 7 in Chemistry, Manufacturing and Controls (CMC) 1 more

Polysorbate Degradation Risk Assessment Evaluate the risk of polysorbate (PS20/PS80) degradation in biologic drug products by identifying enzymatic (residual host cell lipase/esterase) and oxidative degradation pathways and free fatty acid particle...

Data Science/Bioinformatics

Discovery In Silico Drug Dynamics Develop In Silico model of a drug candidate with a biological system with applications such as Pro-drug Predictions, ADME-PK Due Diligence, Brain-Barrier Permeability Simulation, Drug Absorption Simulation, In Silico...
Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.

Discovery Chemistry

Chiral Synthesis Synthesize a compound by a method that favors formation of a specific enantiomer or diastereomer.
Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.

Show all 10 in Discovery Chemistry 4 more

LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

DNA & RNA

Amplified Fragment Length Polymorphism Detection Detect DNA polymorphisms based upon restriction enzyme digestion and PCR.
cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
DNA Extraction Extract DNA from an original source.
DNA Library Screening Screen genomic or cDNA libraries for positive clones.

Show all 25 in DNA & RNA 19 more

DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
DNA Sequencing Determine the nucleotide sequence of DNA samples.
DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
Genotyping Examine a DNA sequence to identify specific genetic varients .
Long Read Sequencing Long read sequencing is used in genomics to sequence long fragments of DNA, enabling the ability to span complex regions of the genome.
mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
qPCR Analysis Measure the accumulation of PCR products in real time.
Restriction Fragment Length Polymorphism Identification Uses gel electrophoresis to identify differences in restriction fragment lengths produced by enzymatic digestion of DNA.
RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
RNAseq and DNAseq library preparation and sequencing DNA/RNA sequencing and preparations
Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Consulting Services Work with consultants who provide expert advice in various areas of research and technology.

In Vitro ADME

CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.

In Vitro Assays

Assay Development Construct or create new assays or modify existing ones.
Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
ELISpot Assay and Testing Detect low levels of antigens.
Glucose Release Assay Determine free glucose levels in biological samples.

Show all 12 in In Vitro Assays 6 more

HTS Assay Development Develop assays to use in high throughput screening.
Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
Serine Protease Assay Detect apoptosis by measuring protease activity.
Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
Histone Acetyltransferase (HAT) Assays Use biochemical, cell-based or in vivo assays to measure histone acetyltransferase activity.
Histone Deacetylase (HDAC) Assays Use biochemical, cell-based or in vivo assays to measure histone deacetylase activity.
In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.

Show all 18 in In Vitro Pharmacology 12 more

Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
PARP Assays Use biochemical, cell-based or in vivo assays to measure PARP activity.
Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
Phosphodiesterase Assays Measure phosphodiesterase activity in biochemical and cell-based assays.
Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
Protease Assay Measure protease activity in biochemical and cell-based assays.
Protein/Enzyme Targets For requesting Protein/Enzyme Targets
Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.
UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.

Product Orders

Kits and Reagents Submit a request to multiple vendors for kits and reagents.

Protein Sciences

Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
Antimicrobial Peptide Synthesis Make a peptide with anti-microbial activities.
Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.

Show all 22 in Protein Sciences 16 more

Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
Protein Purification Isolate native or recombinant proteins from a sample.
Protein Sequencing Determine the amino acid sequence of protein or peptide.
Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.

Scientific Data Services

Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Data and Text Mining Derive structured data from free text in order to become accessible for data-mining algorithms.
Data Curation Organize and integrate data collected from various sources to ease data discovery and retrieval.
Genome Data Analysis Analyze genomic DNA, RNA and protein sequence data.
High-Performance Computing Compute using higher performing parallel processing.
Large Language Models Use of Large Language models in target discovery, clinical trial design and development, analysis of clinical trial data and regulatory submissions. Services are tailored to the problem, specific context of biopharma.

Show all 9 in Scientific Data Services 3 more

Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
Software Tools Software tool for statistical analysis, data mining, genome annotation or NGS data analysis.

Testing Services

Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
Microbiological Sterility Testing Test the presence of viable microorganisms.
USP <62> Microbial Limits Test Determine the presence or absence of specific microorganisms.

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