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acCELLerate
acCELLerate is listed as a small business research supplier in the Scientist.com network, with 5 sites in 2 countries.
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Sites
5
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Chromosomal Characterization Establish karyotype/chromosome profile by cytogenetic analysis of cell preparation.
Show all 10 in Cell Culture and Characterization
- Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
- Mycobacterium Screening Detect and distinguish between mycobacterium strains and species.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
- STR Profiling - Microsatellite Short Tandem Repeat Confirm cell line identity and detect cross-contamination.
Chemical and Compound Analysis
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Show all 54 services
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Human Biological Samples
- Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
In Vitro ADME
- Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
- Multidrug Resistance Identify potential causes of drug-drug interactions.
- Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Fully Automated Assays Develop and perform assays that require no manual steps
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
Show all 10 in In Vitro Assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
- Microbiology Study microbes and their role in human health.
- Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
In Vitro Pharmacology
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Target Identification Identify the target(s) of a biologically active substance.
In Vitro Toxicology
- Cardiac Channels Measure the arrhythmia producing potential of test compounds.
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
- Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
Show all 10 in In Vitro Toxicology
- Genotoxicity Evaluate potential of a compound to cause mutations and chromosomal aberations
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
- hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Protein Sciences
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
REACH Services
- In Vitro REACH Services Perform skin or eye irriation tests, sensitivily and geneotoxicity tests
- OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
- OECD 476: In Vitro Mammalian Cell Gene Mutation Test (Mouse Lymphoma Assay) Determine if a compound is mutagenic by using cultured mammalian cells.
- OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Other services
- New Request
- Website
- www.accellerate.me
Where it operates
Sites by country, with the cities in each.
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Germany 3 sites
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United States 2 sites
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