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Research supplier
SkinAxis LLC
SkinAxis LLC is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Biomarkers
- Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
- Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Show all 11 in Biomarkers
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
Show all 14 in Cell Culture and Characterization
- Cell Line Construction Create new recombinant cell lines to exact specifications.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- Custom 3D Microtissue Development Convert cell lines into highly functional 3D microtissues using scaffold-free self-assembly.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
- Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.
- Yeast Cell Culture Grow yeast strains or species.
Show all 57 services
Chemistry, Manufacturing and Controls (CMC)
- Subcellular Fraction Test System Obtain human, minipig, mouse, or rat dermal microsomes as in-stock standard test systems for the development of safer topical and transdermal products.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Human Biological Samples
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Antivirals Measure anti-viral activity in biochemical and cell assays.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
Show all 11 in In Vitro Assays
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
- Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Model Development
- Custom Model Development Develop a custom disease model.
Oncology Models
- 3D Triculture Breast Cancer Model Use tricultures of breast cancer cell lines, hMSCs, and endothelial tubules for evaluating breast cancer progression.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- Low Density Lipoprotein (LDL) Uptake Assay Investigate low density lipoprotein uptake and regulation at the cellular level.
Testing Services
- Collagen Production Test Test the regenerative ability of the skin under the influence of the test sample.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Human Repeat Insult Patch Test (HRIPT) Examples of which include Topical Irritation, Allergenicity, Phototoxicity and Photoallergy testing.
- OECD 442E: Human Cell Line Activation Test (h-CLAT) In vitro skin sensitization test to predict skin sensitization potency.
- Skin Elasticity Testing Measure the skin's ability to resist pressure (firmness) and its ability to return to its original position pre- and post-treatment.
- Skin Lightening Product Test Measure qualitative and quantitative changes in skin pigmentation under the influence of the test sample.
Show all 8 in Testing Services
- SPF Protection Efficacy Evaluation using FDA Final Rule (2011), Cosmetics Europe (COLIPA), ISO 24444
- UVA Protection Efficacy Evaluation of UVA protection using JCIA or ISO 24442
Other services
- New Request
- Organotypic Small Intestinal Tissue Model Use a 3D co-culture model of human intestine for drug toxicity, permeability, drug-drug interaction and metabolism studies.
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
SkinAxis provides multicellular skin equivalent system that reproduce the physiological properties of human skin tissues. These models represent the response of human skin to drug and active ingredient treatment more accurately then animal models. SkinAxis multicellular skin three dimensional tissue models can be customized using cell types engineered to specifically to specifically express gene reporter systems. These advance models allow the faster, more sensitive, and more accurate assessment of the preclinical activity profile of drugs and active compounds. All products by SkinAxis are...
Show the full description
SkinAxis provides multicellular skin equivalent system that reproduce the physiological properties of human skin tissues. These models represent the response of human skin to drug and active ingredient treatment more accurately then animal models. SkinAxis multicellular skin three dimensional tissue models can be customized using cell types engineered to specifically to specifically express gene reporter systems. These advance models allow the faster, more sensitive, and more accurate assessment of the preclinical activity profile of drugs and active compounds. All products by SkinAxis are made in United States of America.
- Professional associations
- BioNJ
- Website
- www.skinaxis.com
Work with SkinAxis LLC on Scientist.com
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