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Mitsui Knowledge Industry

Mitsui Knowledge Industry is listed as a large business research supplier in the Scientist.com network, with 1 site in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

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Type of company: Large business

Agricultural Sciences Compliance and Quality Control Measures

Master Seed Testing Test your Master Seed Bank or Master Virus Seed Stock (MVSS) to insure that the Working Virus Bank or Working Virus Seed Stock (WVSS) remains the same genotype and phenotype as the initial Master Seed Bank.

Antibodies

Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.

Bioimaging

Mass Spectrometry Imaging Visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses

Biomarkers

Focus Forming Assay Use colorimetric or immunofluorescence-based readouts to quantify virions prior to any plaque formation.
Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.
Protein Tomography Visualize individual proteins or complexes in three dimensions using COMET (Constrained Maximum Entropy Tomography) software.
Whole Transcriptome Amplification Amplify total RNA from a single cell.

Cell Culture and Characterization

Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Show all 127 services 113 more

Chemical and Compound Analysis

Accelerator Mass Spectrometry Detect trace levels of naturally-occurring radionuclides and stable nuclides.
Atomic Absorption Analysis Measure the elemental composition of a diverse array of samples.
Field Desorption Mass Spectrometry Use high potential fields to detect intact molecular ions of an analyte.
Focused Ion Beam Apply a highly focused beam of gallium ions to remove material at high spatial resolution.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Inductively Coupled Plasma (ICP) Analysis Characterize ultra-small levels of multiple solid analytes simultaneously.

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Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Nano-High Performance Liquid Chromatography Separate and detect low levels of analytes.
NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.

Chemical and Compound Testing

Bacterial Water Analysis Analyzing water samples to identify the bacteria present.

Chemistry, Manufacturing and Controls (CMC)

Hydrogen Deuterium Exchange Mass Spectrometry HDX-MS is a mass spectrometry technique that measures how hydrogen atoms in a protein exchange with deuterium, revealing information about protein structure, dynamics, and interactions. It’s widely used to map binding...
Lipoparticle Technology Capture conformationally intact membrane proteins directly from the cell surface using lipoparticle technology.
Thermo Scientific iCAP Q ICP-MS Expand your analytical capabilities with this complete trace elemental analysis solution for your high-throughput lab.

Clinical Trials

Case Report Monitoring & Auditing Ensure the adequate collection and traceability of clinical data in preparation for review by the FDA.
Clinical Lab Services Comprehensive testing, analysis, and research support for a medical study.
Prospective Explorative Studies Conduct a prospective exploratory study to assess the safety and efficacy of a test drug during clinical trials.
Site Monitoring Maintain oversight over participant's health during a clinical trial.
Site Selection Select clinical trial sites with clinicians who recruit, enroll, treat and evaluate trial patients.
Study/Site Feasibility Study Explore and test study practicality.

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Virtual Clinical Trial Monitoring Platform This digital research platform allows researchers to monitor their clinical trials remotely.

Data Science/Bioinformatics

Discovery Data Management A process that includes acquiring, validating, storing, protecting, and processing required data to ensure the accessibility, reliability, and timeliness of the data for its users.

Discovery Chemistry

LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Time of Flight Mass Cytometry (CyTOF™) Detect and quantify up to 34 different proteins simultaneously on a single-cell level.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Disease Models

Acute Liver Failure Models Measure therapeutic endpoints in animal models of acute liver failure.
Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Cough Models Test the therapeutic efficacy of drug candidates in cough models.
Endometriosis Models Measure therapeutic endpoints in animal models of endometriosis.
Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.

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Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
Malaria Models Measure therapeutic endpoints in animal models of malaria.
Otitis Media Models Measure therapeutic endpoints in animal models of otitis media.
Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.

DNA & RNA

ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
Degradome Sequencing Use parallel analysis of RNA ends (PARE) to detect miRNA targets and analyze patterns of RNA degradation.
DNA Extraction Extract DNA from an original source.
DNA Sequencing Determine the nucleotide sequence of DNA samples.
DNA-lipid interaction analysis Investigate cellular dynamics based on changes in fluorescent properties.

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Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
Linear Based RNA Amplification Perform rapid non-PCR RNA amplificaton.
Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
Poly (A) tail Length Profiling (PAL-Seq) Conduct high-throughput sequencing of individual mRNA poly (A) tails.
Ribosome Profiling Determine which mRNAs are being actively translated using next generation sequencing and specialized messenger RNA (mRNA)
RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
RNAi Pathway Analysis Use high-throughput RNAi genetic screens to elucidate relevant signaling pathways.
shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
Spatial Transcriptomics Determine the sub-cellular localization of mRNA molecules. Use this to identify cellular heterogeneity in tissues, tumors, immune cells and the subcellular distribution of transcripts.
Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.
Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.

General Marketing

Database Management Software Facilitate the collection, tracking and processing of biological facts, statistics and observations.

In Vitro ADME

Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.

In Vitro Assays

Antivirals Measure anti-viral activity in biochemical and cell assays.
Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
Glycobiology Study the structure biosynthesis and biology of carbohydrates
Human Immuno-deficiency Virus Infection CDx Design and validate companion diagnostics for HIV infection that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.
Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.

Medical Communications

Medical Science Liaison (MSL) External Presentation Develop and design Medical Science Liaison External Presentations.

Oncology Models

Muscle Wasting Models Measure therapeutic endpoints in animal models of muscle wasting.
Oral Xenograft Measure therapeutic endpoints in oral cancer models as well as cancer models related to the Pharynx.

Pharmacovigilance

Local Pharmacovigilance Support in International Markets Connect with Pharmacovigilance professionals to uphold the National pharmacovigilance guidelines and regulations.

Protein Sciences

Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
Dynamic Organellar Maps Compare protein maps between two experimental conditions.
Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Integrated Proteomics Package Process an entire Proteomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers

Show all 16 in Protein Sciences 10 more

LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
NMR Determine molecular and protein structure, and validate sample integrity.
Protein Identification Uncover or confirm the identity of a protein.
Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Quantitative MS Quantify small and large molecules in the pg/ml range
Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.
Virus Production Produce high titer viruses, viral expression vectors and vaccines.

Safety Pharmacology

Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.

Scientific Data Services

Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Cloud Computing Request on-demand computer resources specifically relating to large data storage and computing power.
Data and Text Mining Derive structured data from free text in order to become accessible for data-mining algorithms.
Data Curation Organize and integrate data collected from various sources to ease data discovery and retrieval.
Data Infrastructure Design and deploy an information management solution suited to users' specific needs.
Data Lineage & Quality Track the various processes through which data has been created, edited or exchanged.

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Data Quality Framework Manage data quality issues to maintain good quality data outputs.
Database Integration Convert bioinformatics results from multiple data sources (DSs) into a single operational format.
Genome Data Analysis Analyze genomic DNA, RNA and protein sequence data.
High-Performance Computing Compute using higher performing parallel processing.
Ontology Mapping Assign given ontologies to source data. 
Scientific Data Visualization Exploration and reporting of data by means of graphs and plots.
Scientific Pipeline Implementation Design, develop and deploy data analyses workflows.
Semantic Tech & Triplestores Store and retrieve semantic facts.
Software Tools Software tool for statistical analysis, data mining, genome annotation or NGS data analysis.
System Development Plan, create and deploy an information system.

Testing Services

ASTM E2315: Time-Kill Procedure (Antimicrobial Testing Study) Assessment of Antimicrobial Activity Using a Time-Kill Procedure
Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.

Other services

Transcriptome In Vivo Analysis (TIVA) Use TIVA for photo-activated capture of mRNA from a single cell or sub-cellular region.

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