- Supplier site
- Group of sites (click to zoom)
Scientist.com supplier network (site locations)
Research supplier
Symbol Discovery Ltd
Symbol Discovery Ltd is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.
View Symbol Discovery Ltd on Scientist.com
Email me this page as a PDF
Sign in to Scientist.com to open this supplier in your organization's marketplace.
Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Chemical and Compound Analysis
- Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- Chemical Stability Measure the stability of small molecules in solution.
- Chiral Separation Purify therapeutically active isomers of drug candidates.
- Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
Show all 24 in Chemical and Compound Analysis
- Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
- Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
- Energy Dispersive X-ray Spectroscopy Identify and estimate the elemental composition of a sample based on x-ray emission patterns.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Ion Exchange Chromatography Separate and detect analytes.
- Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
- Structural Chemistry Examine the relationship between protein structure and function.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
- Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.
Chemistry, Manufacturing and Controls (CMC)
- Advanced intermediates Sourcing advanced intermediates
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- Bulk Manufacturing Find facilities for large-scale mass production.
- Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Crystallization studies Crystallization studies
Show all 12 in Chemistry, Manufacturing and Controls (CMC)
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- Raw Materials & Ingredients Purchase raw materials, ingredients, or chemicals for personal care, cosmetic, consumer health, and beauty products and substances.
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 72 services
Clinical Consulting
- Data & Risk Management Determine the extent of the risk and the reliability of the data used to access the aforementioned risk.
Discovery Chemistry
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- Compound Purchase Buy compounds, building blocks or compound libraries.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Show all 22 in Discovery Chemistry
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
- Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
- Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Drug Development
- Consulting Services Work with consultants who provide expert advice in various areas of research and technology.
- Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
- Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
In Vitro ADME
- Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.
- Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
In Vitro Pharmacology
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Medical Communications
- Medical Publications Make clear and accurate presentations of scientific and technical data.
Protein Sciences
- Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
- PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
- Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
- Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.
- X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Scientific Data Services
- Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
- Website
- www.symboldl.com
Where it operates
Sites by country, with the cities in each.
-
India 2 sites
Work with Symbol Discovery Ltd on Scientist.com
For prices, more details, or to contact Symbol Discovery Ltd, visit Scientist.com.
Sign in to Scientist.com to open this supplier in your organization's marketplace.