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Nikon Europe BV
Nikon Europe BV is listed as a large business research supplier in the Scientist.com network, with 4 sites in 3 countries.
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Sites
4
Countries
3
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Antibodies
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
- Immunodetection Use antibodies to identify a protein or antigen.
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
- Fluorescence-Lifetime Imaging Microscopy (FLIM) Use FLIM to produce an image based on the differences in the excited state decay rate from a fluorescent sample.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
- Photoactivated Localization Microscopy (PALM) Visualize and localize individual endogenous fluorophores.
Show all 8 in Bioimaging
- Second-Harmonic Generation Imaging Microscopy (SHIM) Visualize biomolecular arrays in cells, tissues, and organisms.
- Single Molecule Localization Microscopy Enable structural resolution of biological samples at the nanometer range using light in the visible spectrum.
Biomarkers
- Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
- HCS Assay Development Requesting services related to HCS assay development.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Show all 8 in Biomarkers
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
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Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Construction Create new recombinant cell lines to exact specifications.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
Show all 7 in Cell Culture and Characterization
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Chemical and Compound Analysis
- Stochastic Optical Reconstruction Microscopy (STORM) Visualize and localize individual fluorescent molecules.
- Total Internal Reflection Fluorescence Microscopy Visualize single molecule fluorescence at a surface to produce high quality images with low background.
Disease Models
- Artery On-A-Chip Platform Assess small blood vessels under near-in vivo conditions.
DNA & RNA
- RNAscope In Situ Assays Profile single-cell gene expression in situ.
- Spatial Transcriptomics Determine the sub-cellular localization of mRNA molecules. Use this to identify cellular heterogeneity in tissues, tumors, immune cells and the subcellular distribution of transcripts.
Human Biological Samples
- Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Assay Development Construct or create new assays or modify existing ones.
- BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Show all 14 in In Vitro Assays
- Cell Painting Cell painting is multiplexed image-based assay used to investigate subtle changes in cellular homeostasis
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- In Vitro Human Cell Assays Request in vitro human cells for assays
- Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
- Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
Protein Sciences
- Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Other services
- 3D Force Microscopy of Cells Measure cell-generated forces in 3D biopolymer networks that mimic the physiological situation of living cells.
Where it operates
Sites by country, with the cities in each.
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Netherlands 2 sites
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Switzerland 1 site
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United Kingdom 1 site
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