TandemAI

TandemAI is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 1

Countries 1

Type of company: New startup

Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.

NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
Homology Modeling Generate models for drug design for enzymes, GPCRs, monoclonal antibodies, transporters and chaperones.
In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.

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LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.

Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Protein/Enzyme Targets For requesting Protein/Enzyme Targets
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

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NMR Determine molecular and protein structure, and validate sample integrity.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Purification Isolate native or recombinant proteins from a sample.

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