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Bio Expert

Bio Expert is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

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Type of company: New startup

Agricultural Sciences Research & Development

Animal Feed Supplements Test for mineral nutrients and medicinal compounds for the prevention or control of disease.

Animal Science and Welfare Audits

Veterinary Support Lab technician and veterinarian services providing support for model organisms and animal husbandry.
Vivarium Support Source procurement, housing, husbandry, and care of laboratory animals as well as designing, building and managing vivarium facilities.

Antibodies

Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
OmniRat Transgenic Animal Platform Produce humanized antibodies using a transgenic rat platform.

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Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
Recombinant Antibody Production Request services related to antibody production services.

Bioimaging

In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.
Thermal and Acoustic Imaging Measure the dielectric and optical properties of biological tissues corresponding to pathological states.

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Biomarkers

Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.

Cell Culture and Characterization

3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
Cell Culture Culture primary or immortalized cell lines.
Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.

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Explant Culture Culture cells obtained from a part or parts of an in vivo structure.

Chemical and Compound Analysis

Adsorption/Desorption Studies Obtain data on groundwater risk assessment.
Ultrasound Tomography Use the transmission and acquisition of ultrasound waves to create a non-invasive technique for imaging.

Chemical and Compound Testing

Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.

Clinical Trials

Post-Marketing (Phase 4) Studies Conduct phase 4 studies for confirming unrecognized safety issues, investigating possible hazards or establishing the expected safety profile of a veterinary medicinal product under market conditions.

Data Science/Bioinformatics

In Silico Nucleic Acid Microarray Analysis Use software to visualize and evaluate gene activity in response to various stimuli.
iVAX technology Design epitope driven vaccines through a web-based toolkit.

Developmental and Reproductive Toxicology (DART)

Embryo-Fetal Development (EFD) Study (Segment II) Test drug candidate in Segment II toxicology services.

Disease Models

Demyelination Models Measure therapeutic endpoints in animal models with demyelination pathology.
Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.

DNA & RNA

ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.

Effectiveness

Veterinary Clinical Field Trials Conduct single- or multi-site clinical trials according to VICH/GCP guidelines in livestock, poultry, and domestic pet species.

Environmental Assessment

Hydrolysis Studies Meet international regulatory guidelines with fully compliant hydrolysis testing.
Terrestrial Effects Studies Assess the exposure and adverse effects of veterinary antibiotics to terrestrial ecosystems.
Veterinary Environmental Assessment Assess whether environmental impacts may occur from the manufacture, use, or disposal of veterinary drugs.

Farm & Livestock Solutions

Animal Feed Analysis Test the content and quality of nutrients and biologically active substances in animal feeds. Some analysis that is conducted on feed include; dry matter, crude ash, ash insoluble in acid (sand), crude protein, crude...

General in vivo Toxicology

Carcinogenicity Study - Rat Conduct a repeat dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
Dose Range Finding Study - Dog /Canine Conduct a study to determine the dose range of your compound in dogs/canines.
General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.

Human Biological Samples

Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.

In Vitro Assays

Cell Proliferation Measure cell number, cell viability and cell division.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
Porcine Cornea Reversibility Assay (PorCORA) Measure corneal damage and recovery in excised porcine corneas.

In Vitro Toxicology

Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
Perfused Heart Examine cardiac contractile strength (inotropic effects), heart rate (chronotropic effects) and vascular effects.
Short Time Exposure (STE) Test Use in vitro eye irritation tests to assess cytotoxicity in SIRC cells (rabbit corneal cell line).

Lab Supplies, Facilities, and Equipment

Lab Equipment Mechanical Design Obtain custom laboratory equipment modification and/or production.
Research Diets for Laboratory Animals Custom mixing and formulation of laboratory animal diets.

Model Development

Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Animal Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study animal lung behavior.
Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.
Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Zebrafish Animal Model Model human disease and development in zebrafish.

Nanotechnology

Nanoparticle Synthesis Create nano-level structures with unique features.
Nanotubes and Nanowires Use nanosensors, electrical probes for biological membranes and transistors for lab-on-chip applications.

Oncology Models

Animal Hypoxia Models Measure therapeutic endpoints in hypoxic animal models.

Pharmacology

In Vivo Pharmacology Study the effects of drug candidates in animal models

Pharmacovigilance

GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Radioanalysis

Stand-alone Radioanalysis of Animal Pre-clinical Samples Conduct analysis of radioactive samples from preclinical radiolabeled studies.

REACH Services

OECD 404: Acute Dermal Irritation/Corrosion This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application.
OECD 406: Skin Sensitisation This method provides information on health hazard likely to arise from exposure to test substance via intradermical injection and/or epidermical application.
OECD 413: Subchronic Inhalation Toxicity: 90-day Study This revised Test Guideline 413 (TG 413) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a period of 90 days, and to provide data for quantitative...
OECD 414: Prenatal Developmental Toxicity Study This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism.
OECD 420: Acute Oral Toxicity - Fixed Dose Procedure A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use...
OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...

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OECD 436: Acute Inhalation Toxicity – Acute Toxic Class Method The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according...
OECD 437: Bovine Corneal Opacity and Permeability Test Method (BCOP) for Identifying Ocular Corrosives and Severe Irritants The Bovine Corneal Opacity and Permeability test method (BCOP) is an in vitro test method that can be used to classify substances as 'ocular corrosives and severe irritants'.
OECD 475: Mammalian Bone Marrow Chromosomal Aberration Test The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese...
OECD 486: Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo The purpose of the unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo is to identify substances that induce DNA repair after excision and removal of a stretch of DNA containing a region of damage...
OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.

Regulatory Consulting

Environmental Fate and Ecotoxicology Data Review Identify relevant endpoints for fate and behavior (metabolism and excretion, degradation and soil adsorption) and toxicity (soil organisms, aquatic organisms, and dung fauna) of animal health products.
Environmental Risk Assessment Conduct EU and US Environmental Assessment (ERA/EA) phases one and two according to VICH guidelines.
Toxicology Data Review Identify relevant toxicological endpoints for “No Observed (Adverse) Effect Level” (NO(A)EL) or “Lowest Observed (Adverse) Effect Level” (LO(A)EL).

Safety Pharmacology

Telemetry Use implantable or external devices to study physiological parameters in model organisms

Target Animal and Human Food Safety

Target Animal Safety (TAS) Studies Evaluate potential harmful effects associated with the use of a new animal drug in a controlled setting.
Tolerance Studies Conduct tolerance studies on target animals of veterinary products.

Other services

Implantable Telemetry for Large Animals Use implantable telemetry to study physiological parameters in large animals, such as dogs, primates, swine, sheep, horses, and cattle among others.
Labskin - 3D Skin Model Obtain a full-thickness human skin model.

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