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Tri-Apex

Tri-Apex is listed as a mid sized business research supplier in the Scientist.com network, with 3 sites in 2 countries.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 3

Countries 2

Type of company: Mid sized business

Developmental and Reproductive Toxicology (DART)

Early-Life Stage Toxicity Test Use survival and growth metrics of embryos or larvae to predict effects or find maximum acceptable value of a toxin.
In Vitro Alternative Model for Assessing Reproductive Toxicity Laboratory-based methods used to evaluate the potential harmful effects of substances on reproduction without using live animals.
Juvenile Toxicity Study - Dog / Canine Conduct a study to determine the differences in toxicity between immature and mature systems in dogs.
Juvenile Toxicity Study - Other Species Conduct a study to determine the differences in toxicity between immature and mature systems in other species.
Juvenile Toxicity Study - Rat Conduct a study to determine the differences in toxicity between immature and mature systems in rats.
Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

General in vivo Toxicology

Effective Dose (ED), 50% Toxicity Test Quantify the diluted toxin needed to induce sub-lethal effects upon constant exposure in half of test organisms.
General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
Repeat Dose Toxicity Study - Dog / Canine Conduct a repeat dose study in dogs to determine the toxicity and toxicokinetic behavior of your compound.

Show all 14 in General in vivo Toxicology 8 more

Repeat Dose Toxicity Study - Monkey / Non-human Primate Conduct a repeat dose study in monkey/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Rat Conduct a repeat dose study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.
Single Dose Acute Toxicity Study - Dog / Canine Conduct a single dose study in Dogs and Canines to determine the toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Monkey / Non-human Primate Conduct a single dose study in Monkeys and Non-human Primates to determine the toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.

Show all 100 services 88 more

In Vitro Toxicology

Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
Cytotoxicity Test for effects on cell viability and proliferation
Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Genotoxicity Evaluate potential of a compound to cause mutations and chromosomal aberations
Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.

Show all 7 in In Vitro Toxicology 1 more

Microelectrode Array Cardiotoxicity Assays Use microelectrode array to measure cardiotoxicity-related activities.

Model Development

Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.

Neurotoxicology

Single Dose Acute Neurotoxicity Study - Other Species Conduct a single dose study in other species to determine the neurotoxicty of your compound.
Single Dose Acute Neurotoxicity Study - Rat Conduct a single dose study in rats to determine the neurotoxicty of your compound.

Other Specialty Toxicology

Cutaneous Phototoxicity Study - Guinea Pig Conduct a study in guinea pigs to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
Cutaneous Phototoxicity Study - Mouse Conduct a study in mice to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
Cutaneous Phototoxicity Study - Other Species Conduct a study in other species to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
Cutaneous Phototoxicity Study - Rat Conduct a study in rats to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
Ocular Phototoxicity Study - Other Species Conduct a study to determine the extent to which your compound is capable of producing phototoxic side effects in ocular tissues of other species.
Ocular Phototoxicty Study - Rat Conduct a study to determine the extent to which your compound is capable of producing phototoxic side effects in ocular tissues of rats.

Show all 12 in Other Specialty Toxicology 6 more

Ototoxicity Study - Monkey / Non-human Primate Conduct a study in monkeys/non-human primates to determine the potential for your compound to cause hearing loss.
Ototoxicity Study - Mouse Conduct a study in mice to determine the potential for your compound to cause hearing loss.
Ototoxicity Study - Other Species Conduct a study in other species to determine the potential for your compound to cause hearing loss.
Phototoxicity Determine whether drug treatment causes light-activated toxic effects.
Semi-Static Acute Toxicity Test Measure toxicity endpoints in aquatic organisms exposed to renewed test solutions at defined intervals of an experiment.
Static Acute Toxicity Test Measure toxicity endpoints in aquatic organisms exposed to a non-renewed test solution for the entire experiment.

REACH Services

Acute Toxicity Study - Predatory Mites (Typhlodromus phri) This study is designed to estimate the acute toxicity of substances to Predatory Mites (Typhlodromus phri), including an option for reproductive toxicity.
Acute Toxicity Study - Soil Mites This study is designed to estimate the acute toxicity of substances to Soil Mites, including an option for reproductive toxicity.
OECD 223: Avian Acute Oral Toxicity Test This Test guideline describes procedures designed to estimate the acute oral toxicity of substances to birds.
OECD 402: Acute Dermal Toxicity This method provides information on health hazard likely to arise from short-term exposure to a test chemical by dermal route.
OECD 403: Acute Inhalation Toxicity This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation.
OECD 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.

Show all 21 in REACH Services 15 more

OECD 410: Repeated Dose Dermal Toxicity: 21/28-day Study This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance.
OECD 411: Subchronic Dermal Toxicity: 90-day Study This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance.
OECD 412: Subacute Inhalation Toxicity: 28-Day Study This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data...
OECD 413: Subchronic Inhalation Toxicity: 90-day Study This revised Test Guideline 413 (TG 413) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a period of 90 days, and to provide data for quantitative...
OECD 414: Prenatal Developmental Toxicity Study This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism.
OECD 416: Two-Generation Reproduction Toxicity This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive...
OECD 420: Acute Oral Toxicity - Fixed Dose Procedure A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use...
OECD 421: Reproduction/Developmental Toxicity Screening Test The test substance is administered in graduated doses to several groups of males and females.
OECD 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance.
OECD 423: Acute Oral toxicity - Acute Toxic Class Method The acute toxic class method set out in this Guideline is a stepwise procedure with the use of 3 animals of a single sex per step. Depending on the mortality and/or the moribund status of the animals, on average 2-4...
OECD 425: Acute Oral Toxicity: Up-and-Down Procedure The method permits estimation of an LD50 with a confidence interval and the results allow a substance to be classified for acute toxicity according to the Globally Harmonised System of classification and labelling...
OECD 426: Developmental Neurotoxicity Study A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development.
OECD 432: In Vitro 3T3 NRU Phototoxicity Test Test the cytotoxic effects of chemical substances and environmental samples on cell membranes.
OECD 436: Acute Inhalation Toxicity – Acute Toxic Class Method The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according...
OECD 452: Chronic Toxicity Studies Evaluate the direct and indirect impact of prolonged and repeated toxin exposure to test organisms.

Safety Pharmacology

Developmental Neurotoxicty Study - Other Species A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development.
Microelectrode Array Neurotoxicity Assays Use microelectrode array to measure neurotoxicity-related activities.
Repeat Dose Neurotoxicity Study - Other Species Conduct a repeat dose study in other species to determine the neurotoxicity of your compound.
Repeat Dose Neurotoxicity Study - Rat Conduct a repeat dose study in rats to determine the neurotoxicity of your compound.

Specialty Dosing Routes

Dermal Toxicology Assess toxicity in rodent dermal testing models.
Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
Intra-Articular Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered directly to the joint.
Intra-Auricular Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the ear.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intracameral implant toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct an intracameral implant toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.

Show all 32 in Specialty Dosing Routes 26 more

Intracameral Implant Toxicity and/or Toxicokinetic Study - Other Species Conduct an intracameral implant toxicity study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct an intracameral implant toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Intracameral Implant Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intracameral implant toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Intrathecal/Intraspinal Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the intrathecal space.
Intravitreal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intravitreal ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Minipig Conduct an intravitreal ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct an intravitreal ocular toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Other Species Conduct an intravitreal ocular toxicity study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct an intravitreal ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intravitreal ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Lethal Dose (LD), 50% Toxicity Test Measure acute toxicity by identifying the amount of pure toxin required to kill half of the experimental subjects.
Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Topical Dermal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to dogs/canines.
Topical Dermal Toxicity and/or Toxicokinetic Study - Minipig Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to minipigs.
Topical Dermal Toxicity and/or Toxicokinetic Study - Monkeys/Non-human Primates Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to monkeys/non-human primates.
Topical Dermal Toxicity and/or Toxicokinetic Study - Mouse Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to mice.
Topical Dermal Toxicity and/or Toxicokinetic Study - Other Species Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to other species.
Topical Dermal Toxicity and/or Toxicokinetic Study - Rabbit Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rabbits.
Topical Dermal Toxicity and/or Toxicokinetic Study - Rat Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rats.
Topical Ocular Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a topical ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Minipig Conduct a topical ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct a topical ocular toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Mouse Conduct a topical ocular toxicity study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct a topical ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct a topical ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rat Conduct a topical ocular toxicity study in rats to determine the toxicity and toxicokinetic behavior of your compound.

Testing Services

In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.

Website: www.tri-apex.com

China Nanjing 2 sites
United States North Wales 1 site

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