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FabGennix International

FabGennix International is listed as a small business research supplier in the Scientist.com network, with 5 sites in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 5

Countries 1

Type of company: Small business

Agricultural Sciences Research & Development

Animal Feed Supplements Test for mineral nutrients and medicinal compounds for the prevention or control of disease.
Diagnostic Reagents Creation of custom reagents and certified standards when commercial source is not available or meeting diagnostic needs.
DNA/Protein analysis Analyze DNA and proteins for allergens, pathogens and species identification.
Vaccines Testing transgenic plants as promising systems for vaccine production.

Animal Science and Welfare Audits

Veterinary Support Lab technician and veterinarian services providing support for model organisms and animal husbandry.
Vivarium Support Source procurement, housing, husbandry, and care of laboratory animals as well as designing, building and managing vivarium facilities.

Antibodies

Affinity Maturation Use mutagenesis to optimize a complementary determining region and increase antibody affinity.
AlphaLISA Quantification of analytes with high sensitivity, wider dynamic range and no wash steps involved.
Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.

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Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse
Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.
Immunodetection Use antibodies to identify a protein or antigen.
In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Integrated Antibody Development Package-US Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Membrane Proteome Array (MPA) Services Use a high-throughput, cell-based platform for profiling antibody specificity that targets human membrane proteins.
Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
OmniRat Transgenic Animal Platform Produce humanized antibodies using a transgenic rat platform.
Pepscan Analysis Screen overlapping peptide sequences to identify linear epitopes.
Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.
Recombinant Antibody Production Request services related to antibody production services.
Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
Yeast Display Discover or optimize eukaryotic proteins and antibodies that contain post translational modifications

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Bioimaging

Ab-Targeted Positron Emission Tomography Visualize sites of HIV replication that are difficult to access by tissue biopsies.
Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.
Cryo-electron Tomography This advanced imaging technique is used to visualize the detailed structures of biological samples at near-atomic resolution in their native state.
Photoactivated Localization Microscopy (PALM) Visualize and localize individual endogenous fluorophores.
Single Molecule Localization Microscopy Enable structural resolution of biological samples at the nanometer range using light in the visible spectrum.

Biomarkers

Autoantibody Testing Screen for the presence of an autoimmune disorder.
Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
Endocrine Assays Use biochemical, cell based or in vivo assays to measure the concentration of hormones.
Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.

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Focus Forming Assay Use colorimetric or immunofluorescence-based readouts to quantify virions prior to any plaque formation.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Insulin Autoantibodies (IAA) Testing Detect the risk or presence of type 1 diabetes in early childhood.
Islet Cell Autoantibodies (ICA) Testing Detect Type 1 diabetes-related autoantibodies.
Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Lipoprotein Associated Phospholipase A2 Testing Assess vascular inflammation and determine the risk for atherosclerosis or arterial plaque rupturing.
Microalbumin/Creatinine Ratio (MACR) Screen for kidney disease or monitor the extent of kidney damage from disease complication.
Multiplex Circulating miRNA Assay Profile miRNAs directly from just 10 μl of crude biofluid or 0.1 ng of purified RNA.
Oxidized Low Density Lipoproteins (LDL) Testing Identify the risk for metabolic syndrome and the development of associated diseases.
Peptide Bioanalysis Analyze the structure of Peptides.
Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
Protein Glycosylation Mapping Technique Map glycosylation sites in proteins using liquid chromatography and mass spectrometry.
Protein Tomography Visualize individual proteins or complexes in three dimensions using COMET (Constrained Maximum Entropy Tomography) software.
Proteocarta™ HCP Detect Services Identify and track host cell proteins (HCP) with mass spectrometry for higher sensitivity and coverage.
SomaScan Proteomic Assay Measure 11,000 protein measurements from a 55-µL sample.
T Cell Epitope Characterization Evaluate the potency and immunodominance of T-cell epitopes within a molecule.

Cell Culture and Characterization

Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
In Vitro Hydrogel-Based Culture of PDXs Enable the extended laboratory culture of cancer PDXs and other primary cells in 3D.
Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Chemical and Compound Analysis

Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
Centrifugal Precipitation Chromatography Separate analytes based on their solubility in ammonium sulfate solution.
Chiral Separation Purify therapeutically active isomers of drug candidates.
Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
Denaturing High Performance Liquid Chromatography Separate mixtures of denatured and reannealed oligos to identify single nucleotide substitutions, deletions and insertions.

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Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Gas Chromatography Gas chromatography is an analytical technique that separates, identifies, and quantifies compounds in a mixture
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
Ion Exchange Chromatography Separate and detect analytes.
Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
Lipid Nanoparticle (LNP) Characterization Lipid nanoparticle (LNP) characterization is the process of comprehensively analyzing the physical and chemical properties of LNPs and their components to understand their structure, quality, and functionality
Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Nano-High Performance Liquid Chromatography Separate and detect low levels of analytes.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Small Angle X-Ray Scattering Obtain low-resolution structures of biopolymers in solution using an x-ray beam.
Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Structural Chemistry Examine the relationship between protein structure and function.
Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Chemical and Compound Testing

USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.

Chemistry, Manufacturing and Controls (CMC)

Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
Hydrogen Deuterium Exchange Mass Spectrometry HDX-MS is a mass spectrometry technique that measures how hydrogen atoms in a protein exchange with deuterium, revealing information about protein structure, dynamics, and interactions. It’s widely used to map binding...
Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Integrated Antibody Development Package-UK Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Integrated Small Molecule Package Process an entire Small Molecule/Compounds Pipeline Project including: Compound Synthesis or Purchase, Compound Analysis/Testing, In Vitro Assays, and Formulation/Reformulation from our bundle of suppliers
Lipoparticle Technology Capture conformationally intact membrane proteins directly from the cell surface using lipoparticle technology.

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Subcellular Fraction Test System Obtain human, minipig, mouse, or rat dermal microsomes as in-stock standard test systems for the development of safer topical and transdermal products.

Clinical Consulting

Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

Clinical Trials

Central Institutional Review Board Services Ensure the safety and protection of human subjects participating in a study.
Digital Recruitment Strategy Design Digital recruitment strategy design involves creating a comprehensive plan that leverages online platforms and technologies to attract, engage, and hire the best talent efficiently.
IP Packaging Proper packaging of pharmaceutical products and goods is crucial to ensure the validity and quality of the product being supplied. Proper investigational product packaging is aided by the use of quality...
Post-Marketing (Phase 4) Studies Conduct phase 4 studies for confirming unrecognized safety issues, investigating possible hazards or establishing the expected safety profile of a veterinary medicinal product under market conditions.
Recruiting Special Populations Recruitment of volunteers who are categorized as part of a special population, or a protected part of the population such as the elderly, women, and children.
Site Selection Select clinical trial sites with clinicians who recruit, enroll, treat and evaluate trial patients.

Commercial Consulting

Production Process Consulting Use expert advice to identify sustainable improvements for manufacturing process operations.

Creative

Case Studies Recruit research participants with a behavioral condition to receive either an investigational behavioral intervention or a behavioral intervention in clinical use.
Infographic Create a quick visual representation of information, data or knowledge.
Product Marketing Bring a product to market.

Data Science/Bioinformatics

Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Discovery In Silico Drug Dynamics Develop In Silico model of a drug candidate with a biological system with applications such as Pro-drug Predictions, ADME-PK Due Diligence, Brain-Barrier Permeability Simulation, Drug Absorption Simulation, In Silico...
Discovery In Silico Proteome Analysis Used to understand the global protein environment, specifically drug-protein interactions.
Proteome Data Analysis Find tools for analysis of homology and similarity, protein function and structural properties.

Developmental and Reproductive Toxicology (DART)

Bioelectronics Evaluate an application (e.g. device) that integrates biological materials and micro and nano-electronics.

Discovery Chemistry

Bio-Layer Interferometry Octet BLI is a label-free, real-time technology used to measure biomolecular interactions by detecting changes in optical interference patterns, offering insights into binding kinetics, affinity, and concentration.
Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
Certified Standards Find certified standards for assays, tests and services.
Chemical Protein Stability Assay (CPSA) Chemical Protein Stability Assay is a proprietary cell lysate‐based chemical protein denaturation technology to confirm protein target engagement. This is accomplished by assessing binding-induced stabilisation...
Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
Compound Purchase Buy compounds, building blocks or compound libraries.

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Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Discovery Molecular Modeling and Simulation Analytics Computational methods to model and study the behavior of molecules, from small chemical systems to large biological molecules.
Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
USP Testing Analytical Reagents Acquire chemical reagents, solution concentrates and volumetric solutions used to evaluate items in USP testing.
USP-NF Grade Chemicals Acquire chemicals that comply with United States Pharmacopeia and National Formulary standards.

Disease Models

Acute Liver Failure Models Measure therapeutic endpoints in animal models of acute liver failure.
Artery On-A-Chip Platform Assess small blood vessels under near-in vivo conditions.
Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
IGA Glomerulonephritis Models Measure therapeutic endpoints in animal models of IgA glomerulonephritis.
Microbiome-Based Skin Disease Technology Modify the skin microbiome and deliver therapeutic proteins to the target.
Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.

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Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.

DNA & RNA

Amplified Fragment Length Polymorphism Detection Detect DNA polymorphisms based upon restriction enzyme digestion and PCR.
Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
DNA Extraction Extract DNA from an original source.

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DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
Nanostring nCounter Use single molecule imaging to count molecules directly and without enzymatic amplification.
Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
Ribosome Profiling Determine which mRNAs are being actively translated using next generation sequencing and specialized messenger RNA (mRNA)
RNA Extraction Isolate total RNA or mRNA from cells or tissues
RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...

Drug Development

Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.

Effectiveness

Antimicrobial Pharmacodynamics Ascertain the effectiveness of an antimicrobial compound and test levels of antibiotic resistance against specific bacterial pathogens.
Bioequivalence Studies for Veterinary Drugs Assess the expected biological equivalence of two proprietary preparations of a veterinary drug.
Field Dose Confirmation Studies Conduct an in vivo study to confirm the effectiveness of a selected drug dose in actual field conditions.
Field Dose Determination Studies Examine the effectiveness of various therapeutic concentrations and durations against natural infections under a variety of field conditions.
In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
Laboratory Dose Confirmation Studies Conduct in vivo studies to confirm the effectiveness of a selected drug dose in the lab.

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Laboratory Dose Determination Studies Compare the effectiveness of three non-zero therapeutic concentrations for various durations to a non-medicated control group, and a non-medicated uninfected control group.
Minimum Bactericidal Concentration (MBC) Test Assess the bactericidal activity of a test compound.
Veterinary Clinical Field Trials Conduct single- or multi-site clinical trials according to VICH/GCP guidelines in livestock, poultry, and domestic pet species.

Farm & Livestock Solutions

Animal Feed Analysis Test the content and quality of nutrients and biologically active substances in animal feeds. Some analysis that is conducted on feed include; dry matter, crude ash, ash insoluble in acid (sand), crude protein, crude...
Food Pathogen Testing of Listeria, salmonella, campylab, 0157E coli.
Herd Productivity Improving reproductive efficiency, productions yields, maintenance of healthy animals by routine biosecurity screening and testing.
Phosphorus Buffering Index Assess the ability of soil to bind phosphorus to predict availability for plant uptake.
Processing Techniques Investigation of mechanisms and kinetics of specific reactions for the improvement and stability of bioactive compounds.
Serology/Immunology Testing for BSE/TSE

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Viral Molecular Diagnostic Determination of genetic markers for virus identification. Detect common infectious agents and foreign animal diseases that may threaten animal or human health.
Virology Virus isolation for identification of new and emerging viruses.

Food Safety & Regulations

Dietary Enzyme Testing Verify actual enzyme activity in the final dietary product.

General Marketing

Database Management Software Facilitate the collection, tracking and processing of biological facts, statistics and observations.

Human Biological Samples

HBS Autoimmune Diseases For requesting Autoimmune Diseases HBS.
HBS Huntington's For requesting HBS Huntington's.
Human Aqueous Humor Acquire fresh/frozen normal aqueous humor based on patient demographics and history.
Human Ascites Acquire fresh/frozen Ascites based on patient demographics, disease stage, treatment and history.
Human Blood by-products For requesting Human Blood By-products
Human Cell Lysates For requesting human Cell lysates.

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Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
Human Plasma Acquire fresh/frozen human plasma

In Vitro ADME

Cell Fractionation Isolate organelles and subcellular components.
Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.

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Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Non Isotopic Labeling Track unlabeled macromolecules through a metabolic pathway or cell.
PharmacoScan - A Pharmacogenomics Tool Understand how genetic variation affects drug absorption, distribution, metabolism, and excretion (ADME) in a microarray plate.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.

In Vitro Assays

Anti-thrombin Assays Use clotting and chromogenic assays to detect and classify anti-thrombin deficiency.
Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
Glycobiology Study the structure biosynthesis and biology of carbohydrates
Glycomics Glycomics is the comprehensive study of glycans, in a biological system, such as a cell or organism

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Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
Immunofocus™ Predict the response to anti PD1/PDL1 directed therapies.
ImmunoSEQ Assay Unmask the identity of millions of T- and B-cell receptors in a single sample using bias-controlled multiplex PCR amplification, high-throughput sequencing, and sophisticated bioinformatics.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
OnTarget™ ctDNA Analysis Detect and monitor circulating tumor DNA in blood with OnTarget™ enrichment technology.
Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
Reporter Virus Particles (RVPs) - Dengue Neutralization Assay Use Dengue Reporter Virus Particles to measure neutralizing antibodies against each of the four Dengue serotypes.
Serine Protease Assay Detect apoptosis by measuring protease activity.
Thrombin Generation Tests Measure the tendency of a plasma sample to form thrombin upon the initiation of coagulation.
Von Willebrand Factor Analysis Detect and classify the Von Willebrand disease sub-type.

In Vitro Pharmacology

Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
Aptamer Products Obtain pre-made aptamers for specific target binding.
ATP Competitive Study Determine whether or not a compound is competitive with ATP.
B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
Cellular Thermal Shift Assay Use a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies.

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Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Assays Use biochemical, cell based or in vivo assays to measure CTLA-4 receptor activity.
Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
Extracellular signal Regulated Kinase Assays Use biochemical, cell based or in vivo assays to measure ERK enzyme activity.
G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
Histone Acetyltransferase (HAT) Assays Use biochemical, cell-based or in vivo assays to measure histone acetyltransferase activity.
Histone Deacetylase (HDAC) Assays Use biochemical, cell-based or in vivo assays to measure histone deacetylase activity.
HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
Human BCL Assays Use biochemical, cell-based or in vivo assays to measure BCL activity.
Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
Mitogen/Extracellular signal-regulated Kinase (MEK) Assays Use biochemical, cell based or in vivo assays to measure MEK enzyme activity.
Mutant B-Raf Assays Use biochemical, cell based or in vivo assays to measure mutant B-Raf enzyme activity.
Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
PARP Assays Use biochemical, cell-based or in vivo assays to measure PARP activity.
Peptide Transporter Assays Use biochemical, cell-based or in vivo assays to measure peptide transporter activity.
Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
Phosphatidylinositol 3-Kinase (PI3K) Assays Use biochemical, cell based or in vivo assays to measure PI3K enzyme activity.
Phosphodiesterase Assays Measure phosphodiesterase activity in biochemical and cell-based assays.
Programmed Death-Ligand 2 (PD-L2) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of PD-L2 ligand.
Protease Assay Measure protease activity in biochemical and cell-based assays.
Protein Kinase B (Akt) Assays Use biochemical, cell based or in vivo assays to measure Akt enzyme activity.
Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Protein/Enzyme Targets For requesting Protein/Enzyme Targets
Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.
SELEX Select and identify highly specific aptamers with binding affinities comparable to traditional antibodies.
Solute-Linked Carrier (SLC) Transporter Inhibition Assays Use biochemical, cell-based or in vivo assays to measure solute-linked carrier transporter activity.
Solute-Linked Carrier (SLC) Transporter Substrate Identification Use biochemical, cell-based or in vivo assays to identify solute-linked carrier transporter substrates.
Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
Target Characterization Characterize potential drug targets during the drug discovery process.
Target Identification Identify the target(s) of a biologically active substance.
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.
Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.

In Vitro Toxicology

ADCC and CDC Assay Services Measure toxicity of antibodies.
CH50 Assays Measure the functional activity of the classical complement activation pathway in serum or other fluid samples.
Cytotoxicity Test for effects on cell viability and proliferation

In Vivo Pharmacokinetics

In Vivo Immunogenicity Study An in vivo immunogenicity study evaluates a substance's ability to trigger an immune response within a living organism.

Lab Supplies, Facilities, and Equipment

Research Diets for Laboratory Animals Custom mixing and formulation of laboratory animal diets.

Management Optimization & Development Strategies

Strategic Planning for Sales of Pesticides Consultation in the regulation of sale, use and testing of pesticidal substances produced in plants and microbes according to FIFRA.

Market Access

Communication & Advertisement Distribution of a range of materials, through various communication channels, to highlight a message containing scientific-related topics
Life Science Reports Life Science reports
Market Research & Business Intelligence Run market feasibility studies, establish customer needs, improve product performance and analyze competition.
Marketing and Commercialization Identify, promote and prove the value of a particular drug to key stakeholders.
Value Dossiers Development Summary document that presents clinical, economic, and humanistic value of an intervention and associated disease state with the supporting evidence, formulated from the perspective of a particular stakeholder...

Medical Communications

Animated Content Development of diverse visual, interactive digital assets like infographics, data visualizations, and short animations to explain complex medical and scientific concepts simply.
Communication Plan Communications plan enables organizations and corporations to effectively deliver information to appropriate stakeholders and customers.
Data Visualization Visualize data collected from clinical trials and/or clinical research.
Distribution Strategy & Channel Recommendations Developing plans for how and where medical content (e.g., publications, training, MOA videos) will be efficiently delivered to the target healthcare audience.
Meeting and Events A gathering of people with a shared purpose, often for business or organizational goals
New Product/Indication Launch Planning Strategic development of the medical affairs communication road map and activities necessary to support the successful introduction of a new therapy or approved use.

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Postcast Production Production of audio content featuring expert interviews, clinical data reviews, or scientific discussions, providing easily digestible learning for healthcare professionals (HCPs).
Poster Design and Development Design and Develop Posters for Poster Symposiums and conferences to effectively convey science information.
Sales Training Modules Develop and distribute sales training modules.
Sales Training Webinar Slide Decks Develop slide decks for sales training webinars.

Model Development

Fresh Functional Human Tissue Muscle Contraction Assays Use fresh functional human tissue to assess muscle contraction with various compounds.
Fresh Functional Human Tissue Muscle Relaxation Assays Use fresh functional human tissue to assess muscle relaxation with various compounds.

Nanotechnology

Drug Delivery Technology Create microstructures that enhance drug metabolism properties.
Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.
Nanoparticle Conjugation and Functionalization Modify biomolecules to enhance structure and function.
Nanostructured Lipid Carriers Formulate nanostructered lipid carriers used in drug delivery systems.

Old Category HEOR, RWE, Market Access

Non-Interventional Studies Examine different aspects of drug usage, including efficacy and safety, under real-life conditions.

Oncology Models

Cachexia Models Measure therapeutic endpoints in animal models of cachexia.
Muscle Wasting Models Measure therapeutic endpoints in animal models of muscle wasting.

Other Specialty Toxicology

Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.

Primary Market Research

Advertising Testing (qual/quant) Assesses reactions to creative advertising materials using both qualitative and quantitative methods. Supports refinement of campaign assets before launch.
Claim Testing - Market Research Validates whether specific product claims are believable, relevant, and persuasive. Ensures alignment with compliance and value messaging.
Cross-Functional Readouts and Workshops Interactive sessions to share findings and align stakeholders across functions. Enhances cross-team decision-making and execution planning.
Detail Aid and Promotional Materials Testing Tests visual aids and promotional content with HCPs for clarity, accuracy, and persuasiveness. Delivers insights for regulatory compliance and effectiveness.
Digital Journey Explores the online behaviors and decision-making patterns of stakeholders. Informs digital strategy, content placement, and platform selection.
Facial Coding Analyzes facial expressions during exposure to stimuli to detect emotional reactions. Provides real-time feedback on engagement and sentiment.

Show all 17 in Primary Market Research 11 more

Iterative concept/message testing with interim adjustments Tests concepts or materials in cycles with refinements after each round based on feedback. Delivers optimized content that evolves with stakeholder input.
Market Opportunity Assessments Quantifies addressable market size, unmet needs, and competitive landscape. Supports go/no-go decisions and commercial forecasting.
Message / Claims testing Iterative research to assess clarity, relevance, and impact of key messages. Delivers validated communications that align with stakeholder expectations.
Message recall and aided/unaided awareness studies Studies that assess brand or campaign awareness with and without prompts. Data is used to measure campaign reach, retention, and comparative brand effectiveness.
Persona Development Synthesizes qualitative and quantitative data to build detailed, actionable profiles of stakeholder archetypes. Supports targeted communications and segmentation strategies.
Recruitment Messaging Evaluation Evaluates how well trial recruitment materials resonate with patients or referring physicians. Optimizes clarity and appeal to improve enrollment rates.
Strategic Recommendations for Brand Teams Delivers synthesized insights and data-driven strategic guidance to commercial teams. Supports brand planning and lifecycle management.
Touchpoint Analysis Maps where and how stakeholders interact with a brand or service across the journey. Identifies high-impact opportunities for engagement.
Tracking - Market Research Longitudinal studies that monitor key metrics like awareness, usage, and satisfaction over time. Supports campaign optimization and lifecycle planning.
Trade & Shopper Testing Assesses how buyers interact with packaging, pricing, and placement in retail environments. Supports point-of-sale strategy and product success.
Volumetric Modelling Uses quantitative data and assumptions to forecast product volume, uptake, and market share. Supports revenue projections and manufacturing planning.

Processing, Packaging, & Preservation

Molecular Distillation Use a high-vacuum short path system to purify temperature-sensitve components or enrich a distillate without using toxic separating solvents.
UV Sterilization & Treatment Sterilize food, medical equipment and other materials using ultra-violet light technologies.

Product Orders

Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Lab Supplies Fill out the details below to request a quote:

Protein Sciences

Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
Antimicrobial Peptide Synthesis Make a peptide with anti-microbial activities.
Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.

Show all 73 in Protein Sciences 67 more

Carbohydrate Isolation Obtain pure monosaccharides, pure polysaccharides or related derivatives from samples.
Carbohydrate Isolation Protocol Development Design and optimize protocols for carbohydrate isolation.
Carbohydrate Structure Characterization Use analytical tools to elucidate carbohydrate structure and physiochemical properties.
Cytokines Find recombinant cytokines or cytokine assays.
Dynamic Organellar Maps Compare protein maps between two experimental conditions.
ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
Fluorescence Polarization Investigate receptor-ligand interactions, protein-DNA interactions, proteolysis and membrane fluidity.
Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
FRET/BRET Detect the location of proteins in living cells and their ability to interact with other proteins.
Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
Immunopeptidome Profiling Identify and analyze peptides presented by MHC molecules
Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
Integrated Protein Production Package Process an entire Protein Production Pipeline Project including: Gene/Oligo Synthesis, Cloning/Subcloning, Protein Expression, Protein Purification, Protein Analysis, and Protein Products from our bundle of suppliers
Integrated Proteomics Package Process an entire Proteomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers
Intracellular Trafficking Intracellular Trafficking is when cells transport molecules and proteins from one location to another within the cell.
Kinase Panel Assays Work with service providers offering biochemical assays to assess the activity of multiple protein kinases simultaneously to identify and characterize kinase inhibitors, understand selectivity trends, and assess...
Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Lentivirus Production Develop lentiviruses and production protocols.
Low Density Lipoprotein (LDL) Uptake Assay Investigate low density lipoprotein uptake and regulation at the cellular level.
Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
MAPPs (MHC-II-associated peptide proteomics) MAPPs, or MHC-II-associated peptide proteomics, is a mass spectrometry technique for identifying peptides from therapeutic proteins that are presented by MHC class II molecules on antigen-presenting cells.
Mass Photometry Perform accurate mass measurement of single molecules in solution, in their native state and without the need for labels.
Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
N-terminal Sequencing Determine the amino acid sequence of an intact protein from its N-terminus.
Native Protein Purification Purify native proteins from sources such as tissue & serum.
Neoantigen Development Develop neoantigens for oncological therapeutics for vaccine development.
NMR Determine molecular and protein structure, and validate sample integrity.
PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
Peptide Array Use biologically active synthetic peptides arranged in a high density format to assess protein interaction.
Peptide Derivatives Acquire chemicals that are peptide derivatives.
Peptide Discovery Identifying and developing new peptides.
Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
Phage Display Use in vitro screening method to identify protein binding partners.
Phosphorylation Analysis Identify phosphorylation sites in target proteins.
Protein Binding Determine drug-protein binding interactions
Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Expression In Plant Cells Express recombinant proteins in plant cells.
Protein Identification Uncover or confirm the identity of a protein.
Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Protein Labeling Find suppliers who offer attaching detectable tags like fluorophores or enzymes to proteins
Protein mapping Interrogate the entire sequence of a protein.
Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
Protein Products Find native and recombinant proteins and peptides.
Protein Purification Isolate native or recombinant proteins from a sample.
Protein Sequencing Determine the amino acid sequence of protein or peptide.
Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.
Quantitative MS Quantify small and large molecules in the pg/ml range
Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.
Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.
Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
The MPS Discovery Engine Discover MAbs against high-value difficult membrane protein targets.
Virus Production Produce high titer viruses, viral expression vectors and vaccines.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Yeast Two Hybrid Search novel interactions or confirm hypothesized protein-protein interactions using pairwise assays.

Raw Materials

Antimicrobial Active Ingredients Acquire antimicrobial active ingredients for making consumer healthcare products.
Cationics Positively charged surfactant molecules.
Drug Actives (Other) Formulate and develop products that contain active ingredients such as salicylic acid, benzoyl peroxide, azelaic acid, tacrolimus, and pimecrolimus.
Film Formers Develop products that produce a continuous film on surfaces.
Humectants Acquire humectants, such as glycerin, propylene glycol, and sorbitol, to use as ingredients in consumer healthcare products.
Non-Surfactant Modify the interface between solid particles and the liquid medium to improve the particles' resistance to settling.

Show all 9 in Raw Materials 3 more

Occlusives Moisturizing agent that work by forming a protective coating on the surface of your skin
Surfactants - Amphoterics, Anionics, Betaines, Ethoxylated Glycerine, Nonionics Acquire surfactants, such as amphoterics, anionics, betaines, ethoxylated glycerine, and nonionics, to use as ingredients in consumer healthcare products.
Weight Control Active Ingredients Acquire weight control active ingredients active ingredients for making over-the-counter medicines.

Real World Evidence & Data

Cohort Study Investigating the causes of disease to establish links between risk factors and health outcomes.

Safety Pharmacology

Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.

Scientific Data Services

Automated Image Analysis Automated Image Analysis
Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Marker Analyses Identify associations between genetic markers and traits of interest to determine markers responsible for human diseases.
Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
Scientific Data Visualization Exploration and reporting of data by means of graphs and plots.
T Cell Epitope Mapping Use peptide libraries make it possible to rapidly identify the epitopes of T-Cells, T-Cell clones, T-Helper Cell Clones, T-cell lines, and unpurified T-cells.

Testing Services

Collagen Production Test Test the regenerative ability of the skin under the influence of the test sample.
OECD 442C: Direct Peptide Reactivity Assay (DPRA) Determine whether a test article satisfies the protein-binding criterion for skin sensitizers.
OECD 442D: ARE-Nrf2 Luciferase Test An in vitro test method (KeratinoSensTM and/or LuSens) that models the second key event in the Adverse Outcome Pathway for Dermal Sensitization.

Service areas:

Biology

United States FRISCO, Frisco, Gunter 5 sites

FabGennix International supplies antibodies, reagents and kits.

Website: www.fabgennix.com

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