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BiomimX

BiomimX is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: New startup

Antibodies

Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse

Bioimaging

Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Screening Biomarker testing analyzes tissue, blood, or fluid samples to identify specific genes, proteins, or molecules that indicate disease, particularly cancer.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.

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Human Primary Cell Isolation Isolate primary cells from various human tissues.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.

Cell Culture and Characterization

3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Cell Culture Culture primary or immortalized cell lines.
Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
Custom 3D Microtissue Development Convert cell lines into highly functional 3D microtissues using scaffold-free self-assembly.

Show all 11 in Cell Culture and Characterization 5 more

Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
Microphysiological system (MPS)/organoid analytics microTMA produced from fixed microtissues (MPS)
Microphysiological Systems/organoid transcriptomics Microphysiological Systems/organoid transcriptomics
Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Show all 104 services 88 more

Developmental and Reproductive Toxicology (DART)

In Vitro Alternative Model for Assessing Reproductive Toxicity Laboratory-based methods used to evaluate the potential harmful effects of substances on reproduction without using live animals.
Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Disease Models

Acute Lung Injury Models Measure therapeutic endpoints in animal models of acute lung injury.
Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Bone Models Measure therapeutic endpoints in animal models of bone disorders.
Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.

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Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.

DNA & RNA

DNA Extraction Extract DNA from an original source.
Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.
Whole Transcriptome Sequencing Whole Transcriptome Sequencing (WTS), or total RNA-Seq, is a comprehensive Next-Generation Sequencing (NGS) technique that analyzes all RNA types, including coding (mRNA) and non-coding RNA (lncRNA, miRNA), within...

General in vivo Toxicology

Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.

Human Biological Samples

Human 3D cultures Provision of 3D culture of Human Primary Cells
Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
Human Endothelial Cells Endothelial cells are specialized epithelial cells that form a single layer lining the inner surface of all blood vessels and lymphatic vessels
Human Epithelial Cells Human epithelial cells are the most abundant cell type in the body and form the outer layer of skin and line various internal organs, including the digestive and respiratory tracts.
Human Fibroblasts Human Fibroblasts play a vital role in forming connective tissue
Human iPSC's For requesting human sourced induced pluripotent stem cells.

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Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
Human Synoviocytes Acquire synoviocytes isolated from human synovial joint tissue.

In Vitro ADME

Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
In Vitro ADME in Vitro ADME services
Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.

In Vitro Assays

3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Cell Proliferation Measure cell number, cell viability and cell division.
Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.

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In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro CAR-T Therapy Chimeric Antigen Receptor T-cell therapy: specialized form of immunotherapy
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Human Cell Assays Request in vitro human cells for assays
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.

In Vitro Pharmacology

Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
In Vitro Bone Models Measure osteoclast activity and bone formation in human or rat osteoclasts.
In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.

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Target Identification Identify the target(s) of a biologically active substance.

In Vitro Toxicology

Cardiac Channels Measure the arrhythmia producing potential of test compounds.
Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
Cytotoxicity Test for effects on cell viability and proliferation
Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.

Show all 9 in In Vitro Toxicology 3 more

Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
Microelectrode Array Cardiotoxicity Assays Use microelectrode array to measure cardiotoxicity-related activities.

In Vivo ADME

Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.

In Vivo Pharmacokinetics

Cardiac Safety Assessment Assess cardiotoxicity using microelectrode assay technology.

Model Development

3D Blood-Brain Barrier Model Use an in vitro 3D blood–brain barrier model for real-time visualization of cellular and barrier functions.
Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Custom Model Development Develop a custom disease model.
Non-Human Primate Models Use a single animal species to create one or more disease models.
Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.

Protein Sciences

Cytokines Find recombinant cytokines or cytokine assays.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.

Safety Pharmacology

Respiratory Toxicology Assess difficulty breathing, altered respiration, blood gas changes and blood pH issues due to adverse reactions.
Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.

Specialty Dosing Routes

Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
Intra-Articular Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered directly to the joint.

Testing Services

In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.

Other services

Human Small Airway-On-a-Chip Study human lung inflammation and drug responses in vitro.

Website: www.biomimx.com

Italy Milano 2 sites

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