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Molgenium

Molgenium is listed as a small consultant research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small consultant

Agricultural Sciences Research & Development

  • Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties
  • Vaccines Testing transgenic plants as promising systems for vaccine production.

Antibodies

  • Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
  • Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.

Biomarkers

  • Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
  • Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
  • Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.

Cell Culture and Characterization

  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.

Chemical and Compound Analysis

  • GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
  • Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Show all 74 services 61 more

Chemical and Compound Testing

  • USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.

Chemistry, Manufacturing and Controls (CMC)

  • Analytical Development and Validation Request services related to Analytical Development and Validation
  • API and Drug Product Stability Testing API and Drug Product Stability Testing.
  • API and Drug Product Storage and Distribution API and Drug Product Storage and Distribution.
  • API and drug product storage and release API and drug product storage and release
  • API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
  • API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
Show all 12 in Chemistry, Manufacturing and Controls (CMC) 6 more
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Compendial test methods Run Compendial test methods (e.g., KF)
  • Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
  • Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
  • Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
  • Impurities in Drugs Risk Assessment Create a risk-based control strategy to determine any toxic elemental impurities that may be present in human medicines.

Clinical Trials

  • IRT Services IVRS and Drug supply services allow research conducting clinical trials to&nbsp;receive real time subject updates,&nbsp;drug supply and shipment tracking, and&nbsp;randomization for the clinical trial.&nbsp;These...

Data Science/Bioinformatics

  • In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
  • Mechanism of Action 3D Animation Brings the science of molecular biology to life through interactive educational experiences.

Discovery Chemistry

  • Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.

Disease Models

  • Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
  • Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
  • Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.

DNA & RNA

  • DNA Sequencing Determine the nucleotide sequence of DNA samples.
  • Linear Based RNA Amplification Perform rapid non-PCR RNA amplificaton.

Drug Development

  • Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
  • Large Molecule Drug Development Consulting Develop large molecule drugs and complex biologics that have a therapeutic effect.
  • Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.
  • Small Molecule Drug Development Consulting Request consulting services related to small molecule development.

Effectiveness

  • Bioequivalence Studies for Veterinary Drugs Assess the expected biological equivalence of two proprietary preparations of a veterinary drug.

Human Biological Samples

  • HBS Oncology For requesting Human biospecimens from Oncology indications
  • Human DNA & RNA Acquire fresh/frozen Human DNA & RNA based on patient demographics, disease stage, treatment and history

In Vitro ADME

  • Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
  • Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
  • Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
  • Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
  • Multidrug Resistance Identify potential causes of drug-drug interactions.
  • PharmacoScan - A Pharmacogenomics Tool Understand how genetic variation affects drug absorption, distribution, metabolism, and excretion (ADME) in a microarray plate.
Show all 10 in In Vitro ADME 4 more
  • Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
  • Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
  • Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
  • Reference Standards Find reference standards for assays, tests and services.

In Vitro Assays

  • Antivirals Measure anti-viral activity in biochemical and cell assays.
  • Assay Development Construct or create new assays or modify existing ones.
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • Serine Protease Assay Detect apoptosis by measuring protease activity.

In Vitro Pharmacology

  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • Target Identification Identify the target(s) of a biologically active substance.

In Vivo Pharmacokinetics

  • Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
  • Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
  • Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.

Medical Communications

  • Investigational Medicinal Product Dossier (IMPD) and Investigational New Drug (IND) Dossier Develop and submit Investigational Medicinal Product Dossier (IMPD) and Investigational New Drug (IND) Dossier
  • Quality Control/ Quality Assurance Documents Develop quality control or quality assurance documents.

Nanotechnology

  • Drug Delivery Technology Create microstructures that enhance drug metabolism properties.
  • Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.

Other Specialty Toxicology

  • Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety

Pharmacovigilance

  • GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Protein Sciences

  • Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
  • Protein Binding Determine drug-protein binding interactions
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
  • Virus Production Produce high titer viruses, viral expression vectors and vaccines.

Safety Pharmacology

  • Drug Discrimination Study - Other Species Conduct a study to investigate the length of psychoactive effects of your compound in other species and conduct dose range finding for further studies.

Target Animal and Human Food Safety

  • Toxicity Test for Veterinary Drugs Use the drug at 10X the recommended dose for 3X the recommended duration to evaluate its safety.

Testing Services

  • Microbiological Sterility Testing Test the presence of viable microorganisms.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Germany Duesseldorf 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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