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Kymos
Kymos is listed as a mid sized business research supplier in the Scientist.com network, with 4 sites in 3 countries.
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Sites
4
Countries
3
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Bioimaging
- Mass Spectrometry Imaging Visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses
Biomarkers
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
- Endocrine Assays Use biochemical, cell based or in vivo assays to measure the concentration of hormones.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Show all 10 in Biomarkers
- Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Peptide Bioanalysis Analyze the structure of Peptides.
- Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
- Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
Chemical and Compound Analysis
- Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Atomic Absorption Analysis Measure the elemental composition of a diverse array of samples.
- Chemical Stability Measure the stability of small molecules in solution.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Show all 27 in Chemical and Compound Analysis
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Inductively Coupled Plasma (ICP) Analysis Characterize ultra-small levels of multiple solid analytes simultaneously.
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Structural Chemistry Examine the relationship between protein structure and function.
- Viscosity Testing Evaluate the fluid flow properties of liquids for product evaluation and quality control.
Show all 99 services
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API and drug product storage and release API and drug product storage and release
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Show all 9 in Chemistry, Manufacturing and Controls (CMC)
- Compendial test methods Run Compendial test methods (e.g., KF)
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- ICH-compliant stability testing Perform ICH-compliant stability testing
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Leachable and extractable testing Leachable and extractable testing
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
DNA & RNA
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
- Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
Show all 9 in DNA & RNA
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
In Vitro ADME
- Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Microbiology Study microbes and their role in human health.
In Vitro Pharmacology
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Medical Communications
- Pharmacodynamic/ Pharmacokinetic Reports Create Pharmacodynamic/ Pharmacokinetic reports to report to the appropriate regulatory bodies.
- Toxicology Reports Create pre-clinical toxicology reports.
Other Specialty Toxicology
- Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
- Raw Materials Testing Verify that raw materials are sterile and not contaminated by mycoplasma, virus or other microorganisms.
Pharmacovigilance
- GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.
Protein Sciences
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
- Protein Identification Uncover or confirm the identity of a protein.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Sequencing Determine the amino acid sequence of protein or peptide.
- Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.
Show all 8 in Protein Sciences
- Quantitative MS Quantify small and large molecules in the pg/ml range
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
- Microbiological Sterility Testing Test the presence of viable microorganisms.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
- Website
- kymos.com
Where it operates
Sites by country, with the cities in each.
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Spain 2 sites
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Germany 1 site
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Italy 1 site
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