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Isomerase
Isomerase is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.
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Sites
3
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Research & Development
- Gene Isolation and cloning Development of methods for isolation of gene(s) of interest.
Bioimaging
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
Biomarkers
- Peptide Bioanalysis Analyze the structure of Peptides.
Cell Culture and Characterization
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Mycobacterium Screening Detect and distinguish between mycobacterium strains and species.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
- Yeast Cell Culture Grow yeast strains or species.
Chemical and Compound Analysis
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- Chemical Stability Measure the stability of small molecules in solution.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- Ion Exchange Chromatography Separate and detect analytes.
Show all 16 in Chemical and Compound Analysis
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Natural Product Libraries Find microbial, botanical and marine sources of natural products.
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Show all 64 services
Chemistry, Manufacturing and Controls (CMC)
- API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
Commercial Consulting
- Production Process Consulting Use expert advice to identify sustainable improvements for manufacturing process operations.
Discovery Chemistry
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
DNA & RNA
- cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
- Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- DNA Extraction Extract DNA from an original source.
- DNA Library Screening Screen genomic or cDNA libraries for positive clones.
- DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
Show all 15 in DNA & RNA
- DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
- DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
- Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
- Genomic DNA cloning Clone and propagate genomic DNA inserts of 5-50kb.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Effectiveness
- Minimum Bactericidal Concentration (MBC) Test Assess the bactericidal activity of a test compound.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- ELISpot Assay and Testing Detect low levels of antigens.
- Glucose Release Assay Determine free glucose levels in biological samples.
- Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Protein Sciences
- Antimicrobial Peptide Synthesis Make a peptide with anti-microbial activities.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
- Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
- Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Show all 12 in Protein Sciences
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Testing Services
- CLSI M26-A: Minimum Bactericidal Concentration (MBC) Determine the lowest concentration of an antimicrobial agent that is lethal to the target bacteria in vitro.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Website
- www.isomerase.com
Where it operates
Sites by country, with the cities in each.
-
United Kingdom 3 sites
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