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Shanghai Kylinlab Co., Ltd.

Shanghai Kylinlab Co., Ltd. is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Bioimaging

  • Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.

Biomarkers

  • Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
  • Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
  • Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
  • Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.

Cell Culture and Characterization

  • Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.

Chemical and Compound Analysis

  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.

Disease Models

  • Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
  • Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
  • Cognition Models Measure therapeutic endpoints in animal models of cognition.
  • Electroencephalogram EEG Models Record electrical activity along the scalp of animal models or human patients.
  • General Pain Models Measure therapeutic endpoints in animal models of general pain.
  • Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
Show all 21 in Disease Models 15 more
  • In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
  • Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
  • LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
  • Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
  • Morris Water Maze Investigate spatial learning and memory in rodents.
  • Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
  • Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
  • Optogenetics (rodent behavioral testing) Use light to selectively control the molecular events in cells of living organisms.
  • Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
  • Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
  • Pain Models Test therapeutic efficacy of drug candidate in pain model.
  • Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
  • Schizophrenia Models Measure therapeutic endpoints in animal models of schizophrenia.
  • Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
  • Stroke Models Measure therapeutic endpoints in animal models of stroke.
Show all 90 services 77 more

DNA & RNA

  • qPCR Analysis Measure the accumulation of PCR products in real time.

In Vitro Assays

  • Assay Development Construct or create new assays or modify existing ones.
  • In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.

In Vitro Pharmacology

  • Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
  • Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
  • In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.
  • Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
  • Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.
Show all 8 in In Vitro Pharmacology 2 more
  • Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

In Vivo Pharmacokinetics

  • In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
  • In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…

Model Development

  • Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
  • Animal Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study animal lung behavior.
  • Custom Model Development Develop a custom disease model.
  • Disease Model Database For sourcing disease models.
  • Human Precision-Cut Intestinal Slice Model Acquire a fresh phenotypically-accurate model to study human intestinal behavior.
  • Human Precision-Cut Liver Slice Model Acquire a fresh phenotypically-accurate model to study human liver behavior.
Show all 17 in Model Development 11 more
  • Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
  • Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
  • Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
  • PiggyBac Transgenic Mouse Service Obtain single-copy transgenic embryos with consistent expression of any desired transgene.
  • Pseudopregnant CD1 Mouse Use a single animal species to create gene-modified mouse models.
  • Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
  • SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
  • Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
  • Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
  • Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
  • Transgenic Models Create animal models engineered for use in a specific therapeutic area.

Neurotoxicology

  • Single Dose Acute Neurotoxicity Study - Other Species Conduct a single dose study in other species to determine the neurotoxicty of your compound.
  • Single Dose Acute Neurotoxicity Study - Rat Conduct a single dose study in rats to determine the neurotoxicty of your compound.

Oncology Models

  • Animal Hypoxia Models Measure therapeutic endpoints in hypoxic animal models.
  • Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
  • Endocrine System Xenograft Xenografts derived from organs and glands of the Endocrine system. This include samples from the Pituitary Gland, Thyroid, and Adrenals.
  • Muscle Wasting Models Measure therapeutic endpoints in animal models of muscle wasting.
  • Nervous System PDX Patient derived xenografts relating to the components of the Nervous System. This includes PDX from the Brain, Spinal Cord, and Nerves.
  • Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
Show all 9 in Oncology Models 3 more
  • Reproductive System PDX Patient derived xenografts relating to reproductive systems. This includes PDX from reproductive organs such as the Ovaries, Cervix, Breasts, Testes, Prostate, and Scrotum.
  • Urinary System PDX Patient Derived Xenografts relating to organs that comprise the Urinary system. This includes, but is not limited to, samples from the Kidneys, Liver, and Bladder.
  • Urinary System Xenografts Xenografts derived from organs of the Urinary system. This includes, but is not limited to, xenografts from the Bladder, Kidney, and Urethra.

Protein Sciences

  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

Safety Pharmacology

  • Abuse Liability Determine the dependence potential of a therapeutic.
  • Conditioned Place Preference or Aversion Study - Mouse Conduct a study to establish the aversion or conditioned place preference and determine the motivational effect of your compound in mice.
  • Conditioned Place Preference or Aversion Study - Rat Conduct a study to establish the aversion or conditioned place preference and determine the motivational effect of your compound in rats.
  • Developmental Neurotoxicty Study - Other Species A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development.
  • Drug Discrimination Study - Other Species Conduct a study to investigate the length of psychoactive effects of your compound in other species and conduct dose range finding for further studies.
  • Implanted Telemetry Study - Other Species Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in other species.
Show all 15 in Safety Pharmacology 9 more
  • Implanted Telemetry Study - Rat Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in rats.
  • Repeat Dose Neurotoxicity Study - Other Species Conduct a repeat dose study in other species to determine the neurotoxicity of your compound.
  • Repeat Dose Neurotoxicity Study - Rat Conduct a repeat dose study in rats to determine the neurotoxicity of your compound.
  • Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
  • Seizure Liability Study - Other Species Conduct a study to determine the seizure risk of your compound in other species.
  • Seizure Liability Study - Rat Conduct a study to determine the seizure risk of your compound in rats.
  • Self Administration Study - Other Species Conduct a study to investigate the potential addictive characteristics of your compound in other species.
  • Self Administration Study - Rat Conduct a study to investigate the potential addictive characteristics of your compound in rats.
  • Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.

Specialty Dosing Routes

  • Repeat Dose Intranasal Study - Mouse Conduct a repeat dose intranasal study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Rat Conduct a repeat dose intranasal study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Rats Conduct a repeat dose intravenous infusion study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Mouse Conduct a single dose intranasal study in mice to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Rat Conduct a single dose intranasal study in rats to determine the toxicokinetic behavior of your compound.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • China Shanghai 2 sites

Source: Scientist.com supplier network (site locations)

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