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AlpHelix Biosciences
AlpHelix Biosciences is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.
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Sites
1
Countries
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
- Immunodetection Use antibodies to identify a protein or antigen.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Biomarkers
- Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
Cell Culture and Characterization
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Chemical and Compound Analysis
- Structural Chemistry Examine the relationship between protein structure and function.
Chemistry, Manufacturing and Controls (CMC)
- Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
- Lipoparticle Technology Capture conformationally intact membrane proteins directly from the cell surface using lipoparticle technology.
Discovery Chemistry
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Show all 47 services
In Vitro ADME
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
In Vitro Pharmacology
- ATP Competitive Study Determine whether or not a compound is competitive with ATP.
- Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
- Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
- Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
Show all 18 in In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
- Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
- Peptide Transporter Assays Use biochemical, cell-based or in vivo assays to measure peptide transporter activity.
- Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.
- Protein/Enzyme Targets For requesting Protein/Enzyme Targets
- Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
- Solute-Linked Carrier (SLC) Transporter Inhibition Assays Use biochemical, cell-based or in vivo assays to measure solute-linked carrier transporter activity.
- Solute-Linked Carrier (SLC) Transporter Substrate Identification Use biochemical, cell-based or in vivo assays to identify solute-linked carrier transporter substrates.
- Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
- Phage Display Use in vitro screening method to identify protein binding partners.
Show all 11 in Protein Sciences
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
- Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Scientific Data Services
- Systems Biomedicine Analyze complex interactions in biological systems with interdisciplinary scientific teams.
Other services
- Qube - High Throughput Screening Screen large compound libraries for ion channel blockers and modulators.
- Website
- www.alphelix.com
Where it operates
Sites by country, with the cities in each.
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China 1 site
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