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Lab4Paws
Lab4Paws is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Anatomic Pathology
- Immunohistochemistry Services Prepare, stain and label with histological and immunological reagents, then evaluate slide preparation of cells or tissue.
Biomarkers
- Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
- Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
- Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Show all 9 in Biomarkers
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Custom 3D Microtissue Development Convert cell lines into highly functional 3D microtissues using scaffold-free self-assembly.
- H & E Services For requesting services related to H&E Services
Show all 9 in Cell Culture and Characterization
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
- Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Show all 52 services
Disease Models
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Fixed Tissue Acquire Human fixed tissue based on patient demographics, disease stage, history and treatment.
In Vitro ADME
- Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Show all 7 in In Vitro ADME
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Show all 7 in In Vitro Assays
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
- Toxicology- in vitro Toxicity testing and model development in vitro on developmental and adult neurotoxicity
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Model Development
- Custom Model Development Develop a custom disease model.
Non-Human Biospecimen
- Dog / Canine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Dog / Canine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Dog / Canine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Oncology Models
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
Testing Services
- Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
Other services
- Organotypic Small Intestinal Tissue Model Use a 3D co-culture model of human intestine for drug toxicity, permeability, drug-drug interaction and metabolism studies.
- Website
- www.lab4paws.com
Where it operates
Sites by country, with the cities in each.
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Germany 2 sites
Work with Lab4Paws on Scientist.com
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