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Eurofins Bioanalytical Services
Eurofins Bioanalytical Services is listed as a mid sized business research supplier in the Scientist.com network, with 5 sites in 3 countries and 3 service areas.
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Sites
5
Countries
3
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody Reagents Request information or a price quote for Antibody Reagents services
Biomarkers
- Autoantibody Testing Screen for the presence of an autoimmune disorder.
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
Show all 11 in Biomarkers
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Cell Culture and Characterization
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Line Construction Create new recombinant cell lines to exact specifications.
Chemical and Compound Analysis
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- NBE RIB 2/5 BA Request information or a price quote for GLP Large Molecule Bioanalysis services and products
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Show all 87 services
Chemical and Compound Testing
- Nutritional Testing Analyze food safety, vendor specifications, foreign substance identification processes and nutritional labeling.
- Product Testing Ensure product quality standards are met.
Clinical Consulting
- PK PD Modeling & Analysis Examine the relationship between drug metabolism and therapeutic efficacy.
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
- Clinical Research Services Determine the safety and effectiveness of medications and medical devices.
Developmental and Reproductive Toxicology (DART)
- Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.
DNA & RNA
- Genotyping Examine a DNA sequence to identify specific genetic varients .
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
- Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Human Biological Samples
- HBS Amyotrophic Lateral Sclerosis (ALS) For requesting HBS Amyotrophic Lateral Sclerosis (ALS).
- HBS Chronic Obstructive Pulmonary Disease (COPD) Acquire fresh, frozen, or fixed COPD tissue or for requesting other COPD human biospecimen samples.
- Human Cerebral Spinal Fluid (CSF) Acquire fresh/frozen normal cerebrospinal fluid based on patient demographics and history.
- Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.
- Human Synovial Fluid Acquire fresh/frozen normal synovial fluid based on patient demographics and history.
- Human Urine Acquire fresh/frozen normal urine based on patient demographics and history.
In Vitro ADME
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
In Vitro Assays
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
In Vitro Pharmacology
- Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
- Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Show all 14 in In Vitro Pharmacology
- Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
- Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
- Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
- Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.
- Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
- Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
- Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
- Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Other Specialty Toxicology
- Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
- Phototoxicity Determine whether drug treatment causes light-activated toxic effects.
Product Orders
- BioTx General Biotherapeutics analyze therapeutics and drugs via biological means and recombinant DNA. Pre-clinical sample bioanalysis and le...
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
REACH Services
- OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
- OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
- OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
- OECD 475: Mammalian Bone Marrow Chromosomal Aberration Test The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese...
- OECD 476: In Vitro Mammalian Cell Gene Mutation Test (Mouse Lymphoma Assay) Determine if a compound is mutagenic by using cultured mammalian cells.
- OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
Show all 7 in REACH Services
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Safety Pharmacology
- Endocrine Disruptor Screening Use biochemical, cell based or in vivo assays to identify and quantify endocrine-modulating agents.
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
- Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Testing Services
- Bacterial Reverse Mutation Assay Test whether a cosmetic product or ingredient causes DNA mutations in bacteria.
- Ocular Corrosion Testing Use in vitro models to determine whether a product (or ingredient) can cause ocular corrosion.
- Ocular Irritation Test Use human subjects to determine whether a cosmetic product or ingredient can cause ocular irritation.
- OECD 435: Skin Corrosion Test - Membrane Barrier Method Use in vitro models to determine whether a cosmetic product or ingredient can cause skin corrosion.
- OECD 442C: Direct Peptide Reactivity Assay (DPRA) Determine whether a test article satisfies the protein-binding criterion for skin sensitizers.
- OECD 442E: Human Cell Line Activation Test (h-CLAT) In vitro skin sensitization test to predict skin sensitization potency.
Show all 8 in Testing Services
- OECD TG 492: Ocular Irritation Testing Use in vitro skin models to determine whether a product can cause dermal sensitization (e.g. EpiOcular Eye Irritation Test - EIT)
- Phototoxicology Phototoxicity testing identifies and evaluates the potential of chemical agents to induce toxicity upon subsequent exposure to light.
Other services
- New Request
Service areas:
Biology
DMPK
Toxicology
Where it operates
Sites by country, with the cities in each.
-
United States 3 sites
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Taiwan 1 site
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United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Eurofins Bioanalytics Services, a member of Eurofins BioPharma Services, is a CRO supporting preclinical and clinical development of large molecules with a focus on GLP immunogenicity, pharmacokinetic and biomarker testing as well as GMP product stability & potency testing. Eurofins Discovery Services, a member of Eurofins BioPharma Services, is a product and service provider supporting screening, selectivity profiling and safety assessment of compounds in discovery stage using a combination of biochemical and cell based assays for GPCRs, ion channels, kinases and more. We offer...
Show the full description
Eurofins Bioanalytics Services, a member of Eurofins BioPharma Services, is a CRO supporting preclinical and clinical development of large molecules with a focus on GLP immunogenicity, pharmacokinetic and biomarker testing as well as GMP product stability & potency testing.
Eurofins Discovery Services, a member of Eurofins BioPharma Services, is a product and service provider supporting screening, selectivity profiling and safety assessment of compounds in discovery stage using a combination of biochemical and cell based assays for GPCRs, ion channels, kinases and more.
We offer the following services:
- Screening & Profiling Service
- Biomarker Analysis Service
- Immunogenicity Testing Service
- Pharmacokinetic Assay Service
- cGMP Service
- Safety and Liability Screening Panel
- Biosimilar Services
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