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Muriphys

Muriphys is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: New startup

Cell Culture and Characterization

Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Clinical Trials

Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.

Developmental and Reproductive Toxicology (DART)

Juvenile Toxicity Study - Rat Conduct a study to determine the differences in toxicity between immature and mature systems in rats.
Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Disease Models

Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
Cognition Models Measure therapeutic endpoints in animal models of cognition.
Demyelination Models Measure therapeutic endpoints in animal models with demyelination pathology.
Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
Electroencephalogram EEG Models Record electrical activity along the scalp of animal models or human patients.
Excitotoxicity Models Measure therapeutic endpoints in animal models with excitotoxic pathology.

Show all 20 in Disease Models 14 more

General Pain Models Measure therapeutic endpoints in animal models of general pain.
Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
Olfactory Testing Models Measure therapeutic endpoints in animal models of olfactory function.
Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
Schizophrenia Models Measure therapeutic endpoints in animal models of schizophrenia.
Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
Spinal Cord Injury Models Measure therapeutic endpoints in models of spinal cord injury.
Stroke Models Measure therapeutic endpoints in animal models of stroke.
Tinnitus Models Measure therapeutic endpoints in animal models of tinnitus.

Drug Development

Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.
Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
Toxicology Consulting Use models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

Show all 80 services 67 more

General in vivo Toxicology

Carcinogenicity Study - Mouse Conduct a repeat dose, chronic carcinogenicity study in mice to determine the tendency of your compound to produce tumors.
Carcinogenicity Study - Rat Conduct a repeat dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.

Show all 8 in General in vivo Toxicology 2 more

Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.

In Vitro ADME

Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.

In Vitro Toxicology

Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.

In Vivo ADME

Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.

In Vivo Pharmacokinetics

In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
Mouse Efficacy Monotherapy Use mouse models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Ocular Pharmacokinetic (PK) Screening - Rat Conduct a pharmacokinetic screening study in rats that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.

Show all 11 in In Vivo Pharmacokinetics 5 more

Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Model Development

Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.

Neurotoxicology

Single Dose Acute Neurotoxicity Study - Rat Conduct a single dose study in rats to determine the neurotoxicty of your compound.

Oncology Models

Murine Adenocarcinoma 16 (MAC16) Murine Test for therapeutic efficacy of drug candidates in muscle wasting models.
Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.

REACH Services

OECD 407: Repeated Dose 28-day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.

Safety Pharmacology

Conditioned Place Preference or Aversion Study - Mouse Conduct a study to establish the aversion or conditioned place preference and determine the motivational effect of your compound in mice.
Conditioned Place Preference or Aversion Study - Rat Conduct a study to establish the aversion or conditioned place preference and determine the motivational effect of your compound in rats.
Dependence Potential Study - Rat Conduct a study to determine the dependence potential of your compound in rats.
Drug Discrimination Study - Rat Conduct a study to investigate the length of psychoactive effects of your compound in rats and conduct dose range finding for further studies.
Locomotor Activity Assessment Study - Rat Conduct a study to determine the psychostimulant or sedative activity or your compound in rats.
Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.

Show all 8 in Safety Pharmacology 2 more

Repeat Dose Neurotoxicity Study - Rat Conduct a repeat dose study in rats to determine the neurotoxicity of your compound.
Self Administration Study - Rat Conduct a study to investigate the potential addictive characteristics of your compound in rats.

Specialty Dosing Routes

Chronic Intranasal Carcinogenicity Study - Rats Conduct a repeat dose intranasal, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
Dermal Toxicology Assess toxicity in rodent dermal testing models.
Intrathecal/Intraspinal Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the intrathecal space.
Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Repeat Dose Intranasal Study - Mouse Conduct a repeat dose intranasal study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intranasal Study - Rat Conduct a repeat dose intranasal study in rats to determine the toxicity and toxicokinetic behavior of your compound.

Show all 14 in Specialty Dosing Routes 8 more

Repeat Dose Intravenous Infusion Study - Rats Conduct a repeat dose intravenous infusion study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Single Dose Acute Inhalation Study - Rat Conduct a single dose inhalation study in rats to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intranasal Study - Mouse Conduct a single dose intranasal study in mice to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Rats Conduct a single dose intravenous infusion study in rats to determine the toxicokinetic behavior of your compound.
Topical Dermal Toxicity and/or Toxicokinetic Study - Mouse Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to mice.
Topical Dermal Toxicity and/or Toxicokinetic Study - Rat Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rats.
Topical Ocular Toxicity and/or Toxicokinetic Study - Mouse Conduct a topical ocular toxicity study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rat Conduct a topical ocular toxicity study in rats to determine the toxicity and toxicokinetic behavior of your compound.

Testing Services

Phototoxicology Phototoxicity testing identifies and evaluates the potential of chemical agents to induce toxicity upon subsequent exposure to light.

Website: muriphys.com

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