- Supplier site
- Group of sites (click to zoom)
Scientist.com supplier network (site locations)
Research supplier
TopoGEN
TopoGEN is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country and 1 service area.
View TopoGEN on Scientist.com
Email me this page as a PDF
Sign in to Scientist.com to open this supplier in your organization's marketplace.
Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Sites
3
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Cytogenetics Examine the structure and function of the cell, especially chromosomes.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Show all 9 in Biomarkers
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- TUNEL Assay Detect in situ DNA fragmentation.
Cell Culture and Characterization
- Cell Line Construction Create new recombinant cell lines to exact specifications.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
Chemical and Compound Analysis
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Data Science/Bioinformatics
- In Silico Epigenetic Compound Library Screening Use computer-aided methods to discover new compounds against key regulators of epigenetic signaling.
DNA & RNA
- Bisulfite Sequencing (RRBS) Analyze genome-wide methylation profiles on a single nucleotide level.
- Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
- Methylation Specific PCR Determine the methylation status of a CpG site without the need for base-specific endonucleases.
Show all 33 services
In Vitro ADME
- Cell Fractionation Isolate organelles and subcellular components.
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
In Vitro Pharmacology
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
Protein Sciences
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
- Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
- Protein Products Find native and recombinant proteins and peptides.
Show all 8 in Protein Sciences
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
REACH Services
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Service areas:
Biology
Where it operates
Sites by country, with the cities in each.
-
United States 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
TopoGEN is a research diagnostics company that provides innovative products and services for researchers working with topoisomerases and engaged in mechanism based drug discovery and development.
- Website
- topogen.com
Work with TopoGEN on Scientist.com
For prices, more details, or to contact TopoGEN, visit Scientist.com.
Sign in to Scientist.com to open this supplier in your organization's marketplace.