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Franklin Biolabs
Franklin Biolabs is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Animal Science and Welfare Audits
- Veterinary Support Lab technician and veterinarian services providing support for model organisms and animal husbandry.
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Immunodetection Use antibodies to identify a protein or antigen.
Biomarkers
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
Cell Culture and Characterization
- Single Cell DNA Sequencing Examine genetic variations in a single cell.
- Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.
Chemical and Compound Analysis
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.
Show all 63 services
Chemistry, Manufacturing and Controls (CMC)
- Compendial test methods Run Compendial test methods (e.g., KF)
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Disease Models
- Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
DNA & RNA
- cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
- Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
- DNA Extraction Extract DNA from an original source.
- DNA Sequencing Determine the nucleotide sequence of DNA samples.
- DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
- Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
Show all 11 in DNA & RNA
- Long Read Sequencing Long read sequencing is used in genomics to sequence long fragments of DNA, enabling the ability to span complex regions of the genome.
- NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
General in vivo Toxicology
- Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
- Dose Range Finding Study - Other Species Conduct a study to determine the dose range of your compound in other species.
- Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
- Nonclinical Study Management Provide nonclinical study management services to pharmaceutical and biotech companies. The services can be customized to meet the clients needs.
Show all 7 in General in vivo Toxicology
- Nonclinical Study Monitoring Provide nonclinical study monitors throughout the US and Canada to monitor in vivo and in vitro studies are CROs
In Vitro ADME
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- ELISpot Assay and Testing Detect low levels of antigens.
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
Medical Communications
- Pharmacodynamic/ Pharmacokinetic Reports Create Pharmacodynamic/ Pharmacokinetic reports to report to the appropriate regulatory bodies.
- Toxicology Reports Create pre-clinical toxicology reports.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Non-Human Biospecimen
- Monkey / Non-Human Primate / NHP Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Pharmacovigilance
- GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.
Protein Sciences
- Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
- Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
- Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
- Integrated Proteomics Package Process an entire Proteomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers
- LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Show all 13 in Protein Sciences
- Mass Photometry Perform accurate mass measurement of single molecules in solution, in their native state and without the need for labels.
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
- Phosphorylation Analysis Identify phosphorylation sites in target proteins.
- Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Quantitative MS Quantify small and large molecules in the pg/ml range
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Safety Pharmacology
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- NGS: Next Generation Sequencing Data Analysis Use software to interpret data created by RNA-Seq, DNA-Seq, ChIP-Seq and DNA methylation experiments.
- Website
- www.franklinbio.com
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
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