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QPS
QPS is listed as a mid sized business research supplier in the Scientist.com network, with 7 sites in 4 countries and 1 service area.
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Sites
7
Countries
4
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Biomarkers
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
- Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Show all 8 in Biomarkers
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Chemical and Compound Analysis
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
Show all 12 in Chemical and Compound Analysis
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Structural Chemistry Examine the relationship between protein structure and function.
- Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.
Show all 114 services
Chemistry, Manufacturing and Controls (CMC)
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
- Clinical Research Services Determine the safety and effectiveness of medications and medical devices.
- Clinical Trial Design Develop study-related protocols, case report forms (CRFs) and database tools for records management.
- Mass Balance Studies Design a study to determine the mass balance of drug-related material occurring administration of dose, the ratio of parent drug metabolite(s) in circulation, and the primary route of excretion of drug-related material.
- Phase 1-3 Studies Design phase 1-3 studies that seek to identify if a drug is safe, effective, and more efficient than other available treatments on the market.
- Post-Marketing (Phase 4) Studies Conduct phase 4 studies for confirming unrecognized safety issues, investigating possible hazards or establishing the expected safety profile of a veterinary medicinal product under market conditions.
Data Science/Bioinformatics
- Biostatistical Design Use statistics to ensure appropriate pre-clinical and clinical study design.
Developmental and Reproductive Toxicology (DART)
- Pre/Post-Natal Development (PPND) Study (Segment III) - Mouse Conduct a study to quantify the effect of your compound on fetal development, parturition, and post-natal development in mice.
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Disease Models
- Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
- Excitotoxicity Models Measure therapeutic endpoints in animal models with excitotoxic pathology.
- Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
- LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
- Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
- Myelination Models Measure therapeutic endpoints in animal models with induced myelination, remyelination or developmental myelination.
Show all 9 in Disease Models
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
- Olfactory Testing Models Measure therapeutic endpoints in animal models of olfactory function.
DNA & RNA
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
General in vivo Toxicology
- Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
- Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- HBS Alzheimer's Acquire fresh, frozen, or fixed Alzheimer's tissues or other related Alzheimer's HBS.
- HBS Amyotrophic Lateral Sclerosis (ALS) For requesting HBS Amyotrophic Lateral Sclerosis (ALS).
- HBS Asthma For requesting HBS Asthma.
- HBS Autoimmune Diseases For requesting Autoimmune Diseases HBS.
- HBS Cardiovascular Disease Request tissue samples and Bio-specimen samples from patients with Cardiovascular Disease
Show all 31 in Human Biological Samples
- HBS Chronic Obstructive Pulmonary Disease (COPD) Acquire fresh, frozen, or fixed COPD tissue or for requesting other COPD human biospecimen samples.
- HBS Diabetes For requesting HBS Diabetes.
- HBS Fungal Infections Provision of HBS Fungal Infections samples
- HBS Genetic Diseases For requesting Genetic Diseases HBS
- HBS Healthy/Controls For requesting HBS Healthy/Controls
- HBS HepB positive For requesting HBS HepB positive.
- HBS HepC positive For requesting HBS HepC positive
- HBS HIV positive For requesting HBS HIV positive
- HBS Huntington's For requesting HBS Huntington's.
- HBS Kidney Disease Request samples from patients with Kidney Disease
- HBS Leukemia For requesting HBS Leukemia
- HBS Liver Disease Request samples from patients with Liver Disease.
- HBS Neurological Diseases For requesting Neurological Diseases HBS
- HBS Oncology For requesting Human biospecimens from Oncology indications
- HBS Parkinson's For requesting HBS Parkinson's
- HBS Viral Infections For requesting Viral Infection HBS
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- HBS: Human Biological Samples - VMS Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Blood Acquire fresh/frozen human blood based on patient demographics, disease stage, history and treatment.
- Human Blood by-products For requesting Human Blood By-products
- Human Fresh Tissue For requesting fresh human tissue
- Human Frozen Tissue For requesting frozen human tissue.
- Human HSC's For requesting human sourced hematopoetic stem cells
- Human Leukopaks Obtain enriched leukapheresis-derived products from normal peripheral blood.
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
In Vitro ADME
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Show all 7 in In Vitro ADME
- Radiolabeled Tracers Use radiolabeled drug metabolites as radiotracers for measuring desired physiological processes.
In Vitro Assays
- BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- WBAL (Whole Body AL) Whole Body Autoradioluminography (WBAL) and related services can assist you in determining the metabolic fate of your test agen...
In Vitro Pharmacology
- In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
- In Vitro Excitotoxicity Models Use in vitro models to measure therapeutic endpoints associated with excitotoxic pathology.
- Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
- Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
- Qualitative Whole Body Autoradiography Request information or a price quote for Qualitative WBA services
- Quantitative Whole Body Autoradiography (QWBA) Determine the tissue distribution of a radiolabeled compound in Rodent and Non-Rodent Species.
- Quantitative Whole Body Autoradiography (QWBA) - Non-rodent Species Conduct a study to determine the tissue distribution of your compound radiolabeled compound in non-rodent species.
- Quantitative Whole Body Autoradiography (QWBA) - Rodent Species (Mouse, Rat) Conduct a study to determine the tissue distribution of your compound radiolabeled compound in rodent species.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
- Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Model Development
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Non-Human Biospecimen
- Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Protein Binding Determine drug-protein binding interactions
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Scientific Data Services
- WBA Technologies Request information or a price quote for WBA Technologies services. (global industry bodies driving the adoption of next-gen Wi-Fi, 5G, 6G, IoT, and OpenRoaming)
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Other services
- In Vitro Neurodegenerative Disease Platform Use an IVND platform to screen different compounds/drugs in a finely controlled synaptopathies scenario.
- New Request
Service areas:
Biology
Where it operates
Sites by country, with the cities in each.
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United States 4 sites
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India 1 site
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Netherlands 1 site
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Taiwan 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Founded in 1995, QPS is a GLP/GCP-compliant contract research organization (CRO) supporting discovery, preclinical and clinical drug development. We provide quality services to pharmaceutical and biotechnology clients worldwide. Our linearly integrated core competencies include: Neuropharmacology DMPK Toxicology Bioanalysis Translational medicine Early Stage Clinical Research Phase II – IV Clinical Research Program Management Our regional laboratories and testing facilities are located at our headquarters in Newark, DE, USA; Springfield, MO, USA; Miami, FL, USA; Groningen, The Netherlands...
Show the full description
Founded in 1995, QPS is a GLP/GCP-compliant contract research organization (CRO) supporting discovery, preclinical and clinical drug development. We provide quality services to pharmaceutical and biotechnology clients worldwide. Our linearly integrated core competencies include:
Neuropharmacology
DMPK
Toxicology
Bioanalysis
Translational medicine
Early Stage Clinical Research
Phase II – IV Clinical Research
Program Management
Our regional laboratories and testing facilities are located at our headquarters in Newark, DE, USA; Springfield, MO, USA; Miami, FL, USA; Groningen, The Netherlands; Grambach, Austria; Hyderabad, India and Taipei, Taiwan.
- Website
- www.qps.com
Supplier diversity
SAM.gov small-business designations
Minority-owned
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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