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Cell and Tissue Technology (C&TT)

Cell and Tissue Technology (C&TT) is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
  • Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.

Cell Culture and Characterization

  • 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.

Disease Models

  • Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
  • Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
  • Ischemia Models Measure therapeutic endpoints in animal models of ischemia.

Drug Development

  • Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
  • Toxicology Consulting Use models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

Effectiveness

  • In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
  • Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
  • Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
  • Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
  • Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
  • Reference Standards Find reference standards for assays, tests and services.
Show all 7 in In Vitro ADME 1 more
  • Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
Show all 66 services 49 more

In Vitro Assays

  • 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
  • 3Screen™ 3D In Vitro Services 3Screen™ Platform enables complete 3D cell culture characterization.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
  • Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
Show all 16 in In Vitro Assays 10 more
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
  • In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
  • In Vitro Human Cell Assays Request in vitro human cells for assays
  • In Vitro SPF (Sun Protection Factor) Testing Use in vitro test methods to measure the UVA protection performance of sun protection products.
  • Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
  • Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
  • Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
  • Thrombin Generation Tests Measure the tendency of a plasma sample to form thrombin upon the initiation of coagulation.

In Vitro Pharmacology

  • In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
  • In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
  • In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
  • In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
  • In Vitro Hemolysis Assay Evaluate the toxicity of a drug, metabolite or excipient by hemolytic release of hemoglobin in the plasma.
  • In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
Show all 8 in In Vitro Pharmacology 2 more
  • In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.
  • Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.

In Vitro Toxicology

  • Cardiac Channels Measure the arrhythmia producing potential of test compounds.
  • Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
  • Cytotoxicity Test for effects on cell viability and proliferation
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Show all 11 in In Vitro Toxicology 5 more
  • Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
  • Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
  • hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
  • Microelectrode Array Cardiotoxicity Assays Use microelectrode array to measure cardiotoxicity-related activities.
  • Toxicology- in vitro Toxicity testing and model development in vitro on developmental and adult neurotoxicity

Other Specialty Toxicology

  • Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety

Product Development

  • Personal/Consumer Care Product or Service Request relating to the creation, testing or manufacturing of a personal care/consumer health/cosmetic product, ingredient or raw material.

REACH Services

  • In Vitro Skin Sensitization Determine whether a drug or cosmetic product may cause dermal sensitization.
  • OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...

Safety Pharmacology

  • Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.

Scientific Data Services

  • Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)

Testing Services

  • Consumer Care Testing and Substantiation Test personal care products using analytical, in vitro, and microbial test services
  • In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
  • In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
  • Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.

Other services

  • "Myobundles" - 3D Human Muscles Test new drugs and study diseases in functioning human muscle in vitro.
  • 3D Force Microscopy of Cells Measure cell-generated forces in 3D biopolymer networks that mimic the physiological situation of living cells.
  • Labskin - 3D Skin Model Obtain a full-thickness human skin model.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Germany Aachen, Herzogenrath 2 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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