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Dash Bio

Dash Bio is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: New startup

Antibodies

  • Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.

Biomarkers

  • Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
  • Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
Show all 12 in Biomarkers 6 more
  • Multiplex Circulating miRNA Assay Profile miRNAs directly from just 10 μl of crude biofluid or 0.1 ng of purified RNA.
  • Peptide Bioanalysis Analyze the structure of Peptides.
  • Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.
  • Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
  • Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • SomaScan Proteomic Assay Measure 11,000 protein measurements from a 55-µL sample.

Chemical and Compound Analysis

  • Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
  • GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
  • Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 7 in Chemical and Compound Analysis 1 more
  • Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Show all 81 services 68 more

Clinical Consulting

  • Bioanalysis Consulting Expert advice to properly and effectively discover, evaluate, and measure chemical or biological materials.

DNA & RNA

  • qPCR Analysis Measure the accumulation of PCR products in real time.
  • RNAscope In Situ Assays Profile single-cell gene expression in situ.
  • Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.

In Vitro ADME

  • Plasma Stability Assay Determine degradation rate of drug candidates in plasma.

In Vitro Assays

  • 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
  • Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
  • Anti-thrombin Assays Use clotting and chromogenic assays to detect and classify anti-thrombin deficiency.
  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Assay Development Construct or create new assays or modify existing ones.
  • Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
Show all 33 in In Vitro Assays 27 more
  • Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
  • Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • ELISpot Assay and Testing Detect low levels of antigens.
  • Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
  • Epigenetic Profiling In Vitro Assays Test for epigenetic modifications and indicator levels via in vitro assays.
  • Fully Automated Assays Develop and perform assays that require no manual steps
  • Glucose Release Assay Determine free glucose levels in biological samples.
  • HTS Assay Development Develop assays to use in high throughput screening.
  • Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
  • In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
  • In Vitro Human Cell Assays Request in vitro human cells for assays
  • Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
  • Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
  • Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
  • Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
  • Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
  • PrimeFlow™ RNA Assay Reveal the unique kinetics of mRNA and protein in the same cell and identify expression differences as they change over time in response to stimulus.
  • Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
  • Reporter Virus Particles (RVPs) - Dengue Neutralization Assay Use Dengue Reporter Virus Particles to measure neutralizing antibodies against each of the four Dengue serotypes.
  • Serine Protease Assay Detect apoptosis by measuring protease activity.
  • Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
  • Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
  • Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.
  • Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

  • Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
  • B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
  • Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
  • Liposome Immunoassay Use immuno-liposomes for improved signal intensity and detection sensitivity compared to enzyme and fluorescent immunoassays.
Show all 14 in In Vitro Pharmacology 8 more
  • Mammalian Target of Rapamycin Complex Assays Use biochemical, cell based or in vivo assays to measure mTORC enzyme activity.
  • Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
  • Mutant B-Raf Assays Use biochemical, cell based or in vivo assays to measure mutant B-Raf enzyme activity.
  • Phosphatidylinositol 3-Kinase (PI3K) Assays Use biochemical, cell based or in vivo assays to measure PI3K enzyme activity.
  • Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
  • RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.
  • Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
  • Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.

In Vitro Toxicology

  • CH50 Assays Measure the functional activity of the classical complement activation pathway in serum or other fluid samples.

In Vivo Pharmacokinetics

  • Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
  • Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.

Model Development

  • Fresh Functional Human Tissue Efficacy Assays Use fresh functional human tissue to assess pre-clinical efficacy of test compounds.
  • Fresh Functional Human Tissue Safety Assays Use fresh functional human tissue to assess pre-clinical safety of test compounds.

Protein Sciences

  • Kinase Panel Assays Work with service providers offering biochemical assays to assess the activity of multiple protein kinases simultaneously to identify and characterize kinase inhibitors, understand selectivity trends, and assess...
  • Quantitative MS Quantify small and large molecules in the pg/ml range

REACH Services

  • OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.

Other services

  • New Request  

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Boston, Newton 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Professional associations
AAPS, MassBio, Society of Laboratory Automation and Screening (SLAS)
Website
Dash.bio

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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