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Dash Bio
Dash Bio is listed as a new startup research supplier in the Scientist.com network, with 2 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Biomarkers
- Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
- Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
Show all 12 in Biomarkers
- Multiplex Circulating miRNA Assay Profile miRNAs directly from just 10 μl of crude biofluid or 0.1 ng of purified RNA.
- Peptide Bioanalysis Analyze the structure of Peptides.
- Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.
- Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
- Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- SomaScan Proteomic Assay Measure 11,000 protein measurements from a 55-µL sample.
Chemical and Compound Analysis
- Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 7 in Chemical and Compound Analysis
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Show all 81 services
Clinical Consulting
- Bioanalysis Consulting Expert advice to properly and effectively discover, evaluate, and measure chemical or biological materials.
DNA & RNA
- qPCR Analysis Measure the accumulation of PCR products in real time.
- RNAscope In Situ Assays Profile single-cell gene expression in situ.
- Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.
In Vitro ADME
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
In Vitro Assays
- 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Anti-thrombin Assays Use clotting and chromogenic assays to detect and classify anti-thrombin deficiency.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Assay Development Construct or create new assays or modify existing ones.
- Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
Show all 33 in In Vitro Assays
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- ELISpot Assay and Testing Detect low levels of antigens.
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
- Epigenetic Profiling In Vitro Assays Test for epigenetic modifications and indicator levels via in vitro assays.
- Fully Automated Assays Develop and perform assays that require no manual steps
- Glucose Release Assay Determine free glucose levels in biological samples.
- HTS Assay Development Develop assays to use in high throughput screening.
- Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- In Vitro Human Cell Assays Request in vitro human cells for assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
- Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
- Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- PrimeFlow™ RNA Assay Reveal the unique kinetics of mRNA and protein in the same cell and identify expression differences as they change over time in response to stimulus.
- Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
- Reporter Virus Particles (RVPs) - Dengue Neutralization Assay Use Dengue Reporter Virus Particles to measure neutralizing antibodies against each of the four Dengue serotypes.
- Serine Protease Assay Detect apoptosis by measuring protease activity.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
- Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
- Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.
- Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.
In Vitro Pharmacology
- Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
- B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- Liposome Immunoassay Use immuno-liposomes for improved signal intensity and detection sensitivity compared to enzyme and fluorescent immunoassays.
Show all 14 in In Vitro Pharmacology
- Mammalian Target of Rapamycin Complex Assays Use biochemical, cell based or in vivo assays to measure mTORC enzyme activity.
- Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
- Mutant B-Raf Assays Use biochemical, cell based or in vivo assays to measure mutant B-Raf enzyme activity.
- Phosphatidylinositol 3-Kinase (PI3K) Assays Use biochemical, cell based or in vivo assays to measure PI3K enzyme activity.
- Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
- RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.
- Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
- Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.
In Vitro Toxicology
- CH50 Assays Measure the functional activity of the classical complement activation pathway in serum or other fluid samples.
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
- Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.
Model Development
- Fresh Functional Human Tissue Efficacy Assays Use fresh functional human tissue to assess pre-clinical efficacy of test compounds.
- Fresh Functional Human Tissue Safety Assays Use fresh functional human tissue to assess pre-clinical safety of test compounds.
Protein Sciences
- Kinase Panel Assays Work with service providers offering biochemical assays to assess the activity of multiple protein kinases simultaneously to identify and characterize kinase inhibitors, understand selectivity trends, and assess...
- Quantitative MS Quantify small and large molecules in the pg/ml range
REACH Services
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
- Professional associations
- AAPS, MassBio, Society of Laboratory Automation and Screening (SLAS)
- Website
- Dash.bio
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