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Mosaic Biosciences

Mosaic Biosciences is listed as a consultant research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Consultant

Antibodies

  • Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
  • Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
  • Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
  • Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
  • Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
  • Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
Show all 17 in Antibodies 11 more
  • Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
  • Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
  • Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
  • Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
  • Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
  • Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
  • In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
  • Integrated Antibody Development Package-US Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
  • Recombinant Antibody Production Request services related to antibody production services.
  • Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
  • Yeast Display Discover or optimize eukaryotic proteins and antibodies that contain post translational modifications

Biomarkers

  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.

Cell Culture and Characterization

  • Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
  • Cell Culture Culture primary or immortalized cell lines.
  • Cell Line Construction Create new recombinant cell lines to exact specifications.
  • Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Show all 64 services 52 more

Chemistry, Manufacturing and Controls (CMC)

  • Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.

Clinical Consulting

  • Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...

DNA & RNA

  • Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.

Drug Development

  • Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
  • Consulting Services Work with consultants who provide expert advice in various areas of research and technology.
  • Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.

In Vitro Assays

  • Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • Assay Development Construct or create new assays or modify existing ones.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Show all 11 in In Vitro Assays 5 more
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
  • In Vitro Human Cell Assays Request in vitro human cells for assays
  • Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.

In Vitro Pharmacology

  • B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
  • Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.

In Vitro Toxicology

  • ADCC and CDC Assay Services Measure toxicity of antibodies.
  • Cytotoxicity Test for effects on cell viability and proliferation
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.

Protein Sciences

  • Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
  • Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
  • Cytokines Find recombinant cytokines or cytokine assays.
  • ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
  • Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
  • Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Show all 17 in Protein Sciences 11 more
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
  • Phage Display Use in vitro screening method to identify protein binding partners.
  • Phosphorylation Analysis Identify phosphorylation sites in target proteins.
  • Protein Binding Determine drug-protein binding interactions
  • Protein mapping Interrogate the entire sequence of a protein.
  • Protein Purification Isolate native or recombinant proteins from a sample.
  • Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
  • Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Website
mosaicbio.com

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Boulder 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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