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Inspiralis

Inspiralis is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.

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Sites 3
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Agricultural Sciences Research & Development

  • DNA/Protein analysis Analyze DNA and proteins for allergens, pathogens and species identification.

Chemical and Compound Analysis

  • Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
  • Ion Exchange Chromatography Separate and detect analytes.
  • Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
  • Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
  • Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.

In Vitro Assays

  • Assay Development Construct or create new assays or modify existing ones.

In Vitro Pharmacology

  • Phosphodiesterase Assays Measure phosphodiesterase activity in biochemical and cell-based assays.
  • Reversibility Study Determine whether or not a compound inhibits an enzyme reversibly.
  • Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
  • Target Characterization Characterize potential drug targets during the drug discovery process.
  • Target Identification Identify the target(s) of a biologically active substance.
Show all 21 services 9 more

Protein Sciences

  • Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
  • Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
  • Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
  • Protein Purification Isolate native or recombinant proteins from a sample.
Show all 9 in Protein Sciences 3 more
  • Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
  • Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Norwich 3 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Since 1995 we have been supplying topoisimerase products and services to the pharmaceutical industry and academia to aid research in the anti-infectives and anti-cancer markets. Previously trading as John Innes Enterprises, Inspiralis was established upon the research of Professor Tony Maxwell, one of the world's leaders in the field of topoisomerase research. We are located in laboratories adjacent to the academic research centres of the John Innes Centre and the University of East Anglia on the Norwich Research Park. We maintain close links with the academic research group of Professor...

Show the full description

Since 1995 we have been supplying topoisimerase products and services to the pharmaceutical industry and academia to aid research in the anti-infectives and anti-cancer markets. Previously trading as John Innes Enterprises, Inspiralis was established upon the research of Professor Tony Maxwell, one of the world's leaders in the field of topoisomerase research.

We are located in laboratories adjacent to the academic research centres of the John Innes Centre and the University of East Anglia on the Norwich Research Park. We maintain close links with the academic research group of Professor Maxwell, helping us to remain at the forefront of the topoisomerase field. The experience of our staff and the connections with the academic group allow us to provide a high level of support to ensure that researchers are able to get the best results using our products. The same scientists who produce our enzymes and substrates also provide the technical support.

Our aim is to provide pharmaceutical companies, and others involved in drug development, with the necessary tools to develop and screen novel anti-infective and anti-cancer compounds. In order to achieve this we will continue to expand the range of topoisomerase products and screening services we offer.

Website
www.inspiralis.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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