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myotwin
myotwin is listed as a new startup research supplier in the Scientist.com network, with 3 sites in 1 country.
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Sites
3
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
Biomarkers
- Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Custom 3D Microtissue Development Convert cell lines into highly functional 3D microtissues using scaffold-free self-assembly.
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
- Microphysiological system (MPS)/organoid analytics microTMA produced from fixed microtissues (MPS)
- Microphysiological Systems/organoid transcriptomics Microphysiological Systems/organoid transcriptomics
Show all 7 in Cell Culture and Characterization
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Disease Models
- Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
Show all 36 services
DNA & RNA
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Human Biological Samples
- Human iPSC's For requesting human sourced induced pluripotent stem cells.
In Vitro Assays
- Organoid Screening Assay Evaluate the effects of various substances, such as drugs or genetic modifications, on organoids.
In Vitro Pharmacology
- Cardiac Contractility and Force Assays Measurement of active contraction force, passive force and contraction kinetics in 3D engineered human myocardial tissue (eMT) for efficacy and cardiac safety questions, recorded simultaneously with calcium handling...
- Cardiomyopathy Disease Models Human in vitro disease models of hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmogenic cardiomyopathy, Duchenne cardiac phenotype and LPS-induced cardiomyopathy in 3D engineered human...
- Cellular Thermal Shift Assay Use a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies.
- Human Cardiac Fibrosis Models Human in vitro cardiac fibrosis model in 3D engineered human myocardial tissue (eMT) with functional readouts of tissue stiffness, passive force, active force, calcium handling and electrophysiology, for anti-fibrotic...
- In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
Show all 7 in In Vitro Pharmacology
- Myocardial Stiffness Assays Measurement of myocardial stiffness and passive force in 3D engineered human myocardial tissue (eMT) as a preclinical readout for diastolic dysfunction, cardiac fibrosis and structural cardiotoxicity, alongside active...
In Vitro Toxicology
- Cardiac Channels Measure the arrhythmia producing potential of test compounds.
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
- Cytotoxicity Test for effects on cell viability and proliferation
- hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
Show all 8 in In Vitro Toxicology
- Microelectrode Array Cardiotoxicity Assays Use microelectrode array to measure cardiotoxicity-related activities.
- Perfused Heart Examine cardiac contractile strength (inotropic effects), heart rate (chronotropic effects) and vascular effects.
Model Development
- Custom Model Development Develop a custom disease model.
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Testing Services
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
- Website
- myotwin.com
Where it operates
Sites by country, with the cities in each.
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Germany 3 sites
Work with myotwin on Scientist.com
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