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Axolabs
Axolabs is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Show all 7 in Biomarkers
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
Chemical and Compound Analysis
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
Show all 22 in Chemical and Compound Analysis
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Inductively Coupled Plasma (ICP) Analysis Characterize ultra-small levels of multiple solid analytes simultaneously.
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Process Residual Impurities Detection Measure trace levels of impurities.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
- UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.
Show all 88 services
Chemical and Compound Testing
- Limulus Amebocyte Lysate (LAL) Test Detect bacterial endotoxins in raw materials used for the production of cosmetics products.
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
Data Science/Bioinformatics
- In Silico Nucleic Acid Microarray Analysis Use software to visualize and evaluate gene activity in response to various stimuli.
Discovery Chemistry
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Show all 7 in Discovery Chemistry
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
DNA & RNA
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- In Situ Hybridization Localize specific nucleic acid targets using labeled complementary probes.
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
- non-coding RNA Synthesis Prepare non-coding RNA in vitro.
Show all 17 in DNA & RNA
- Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
- Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
- Poly (A) tail Length Profiling (PAL-Seq) Conduct high-throughput sequencing of individual mRNA poly (A) tails.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
- RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
- RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
- RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
- RNAscope In Situ Assays Profile single-cell gene expression in situ.
- siRNA Synthesis Produce high quality siRNAs for gene silencing studies.
In Vitro ADME
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
- Reference Standards Find reference standards for assays, tests and services.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
In Vivo ADME
- Quantitative Whole Body Autoradiography (QWBA) - Non-rodent Species Conduct a study to determine the tissue distribution of your compound radiolabeled compound in non-rodent species.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Nanotechnology
- Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.
Protein Sciences
- Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Elevated Temperature Stability Determine the stability of a product at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
Other services
- New Request
- Website
- www.axolabs.com
Where it operates
Sites by country, with the cities in each.
-
Germany 2 sites
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