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Biotem

Biotem is listed as a small business research supplier in the Scientist.com network, with 4 sites in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 4
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Agricultural Sciences Research & Development

  • Diagnostic Reagents Creation of custom reagents and certified standards when commercial source is not available or meeting diagnostic needs.

Antibodies

  • Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
  • Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
  • Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
  • Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Show all 23 in Antibodies 17 more
  • Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
  • Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
  • Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
  • Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
  • Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
  • Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
  • Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.
  • Immunodetection Use antibodies to identify a protein or antigen.
  • In Silico Humanization Predict epitope binding specificity, increase in vivo half-life and allow rapid modeling and humanization of antibodies.
  • In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
  • Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
  • Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
  • Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
  • Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
  • Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.
  • Recombinant Antibody Production Request services related to antibody production services.
  • Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.

Biomarkers

  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.

Cell Culture and Characterization

  • Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
  • Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
Show all 54 services 41 more

Chemical and Compound Analysis

  • Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
  • Size Exclusion Chromatography Separate and identify analytes based on their molecular size.

Chemistry, Manufacturing and Controls (CMC)

  • Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
  • Integrated Antibody Development Package Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
  • Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
  • Integrated Antibody Development Package-UK Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...

Discovery Chemistry

  • Custom Libraries Find or synthesize mg to kg amounts of target-specific and target-agnostic compounds for HTS and biological profiling.
  • Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
  • Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
  • Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.

DNA & RNA

  • DNA Library Screening Screen genomic or cDNA libraries for positive clones.
  • Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.

In Vitro Assays

  • Assay Development Construct or create new assays or modify existing ones.

In Vitro Pharmacology

  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.

Non-Human Biospecimen

  • Llama Cells, Tissues, and Biofluids Acquire fresh or frozen cells, tissues, and biofluids including but not limited to whole blood, PBMCs, tissue slides, etc.

Product Orders

  • Kits and Reagents Submit a request to multiple vendors for kits and reagents.

Protein Sciences

  • Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
  • Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
  • ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
  • Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Phage Display Use in vitro screening method to identify protein binding partners.
Show all 8 in Protein Sciences 2 more
  • Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

Service areas:

Biology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • France Apprieu, Colombe 4 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Biotem provides antibodies, assay development, and cell culture.

Website
www.biotem-antibody.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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