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GEM FORLAB SrL

GEM FORLAB SrL is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 3

Countries 1

Type of company: Small business

Antibodies

Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
SARS-CoV-2 (COVID-19) Antibodies Search for available SARS-COV-2 antibodies

Biomarkers

Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.

Show all 17 in Biomarkers 11 more

Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.

Cell Culture and Characterization

Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Cell Culture Culture primary or immortalized cell lines.

Show all 84 services 71 more

Chemical and Compound Analysis

Chiral Separation Purify therapeutically active isomers of drug candidates.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
Ion Exchange Chromatography Separate and detect analytes.

Show all 15 in Chemical and Compound Analysis 9 more

Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Process Residual Impurities Detection Measure trace levels of impurities.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.

Chemistry, Manufacturing and Controls (CMC)

Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.

Discovery Chemistry

Certified Standards Find certified standards for assays, tests and services.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.

DNA & RNA

qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
RNA Extraction Isolate total RNA or mRNA from cells or tissues

Human Biological Samples

SARS-CoV-2 (COVID-19) Human Biological Samples Search for available SARS-CoV-2 human biological samples

In Vitro ADME

Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.

Show all 12 in In Vitro ADME 6 more

Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Reference Standards Find reference standards for assays, tests and services.

In Vitro Assays

Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Assay Development Construct or create new assays or modify existing ones.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Proliferation Measure cell number, cell viability and cell division.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
SARS-CoV-2 (COVID-19) Assays Search for Available SARS-CoV-2 Assays

Show all 8 in In Vitro Assays 2 more

Serine Protease Assay Detect apoptosis by measuring protease activity.
Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.

In Vitro Pharmacology

Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
Target Identification Identify the target(s) of a biologically active substance.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation

In Vivo Pharmacokinetics

Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.

Protein Sciences

Cytokines Find recombinant cytokines or cytokine assays.
ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
Protein Binding Determine drug-protein binding interactions
Protein Identification Uncover or confirm the identity of a protein.

Show all 10 in Protein Sciences 4 more

Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Protein mapping Interrogate the entire sequence of a protein.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

Testing Services

CLSI M26-A: Minimum Bactericidal Concentration (MBC) Determine the lowest concentration of an antimicrobial agent that is lethal to the target bacteria in vitro.

Italy Caluso, Busca 3 sites

GEMFORLAB is a scientific service provider devoted to supporting companies belonging to the Life Sciences field. GEMFORLAB services are aimed to solve problems linked to quality, safety, efficacy of products/ compounds subjected to development phase and to identify customized solutions to specific R&D issues. Thanks to its scientific and technological platforms, the quality system, the competences, the flexibility and the versatility of the team to meet customer needs, GEMFORLAB is the partner of choice of small companies, R&D centers and multinational corporations which requires...

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GEMFORLAB is a scientific service provider devoted to supporting companies belonging to the Life Sciences field. GEMFORLAB services are aimed to solve problems linked to quality, safety, efficacy of products/ compounds subjected to development phase and to identify customized solutions to specific R&D issues.
Thanks to its scientific and technological platforms, the quality system, the competences, the flexibility and the versatility of the team to meet customer needs, GEMFORLAB is the partner of choice of small companies, R&D centers and multinational corporations which requires the capability to manage and solve complex problems following regulatory requirements.

Website: www.gemforlab.com

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