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PortaCellTec Biosciences GmbH
PortaCellTec Biosciences GmbH is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Chemical and Compound Analysis
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Disease Models
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
In Vitro ADME
- Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Show all 7 in In Vitro ADME
- Multidrug Resistance Identify potential causes of drug-drug interactions.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
Show all 24 services
In Vitro Pharmacology
- ATP Competitive Study Determine whether or not a compound is competitive with ATP.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
- Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
- Peptide Transporter Assays Use biochemical, cell-based or in vivo assays to measure peptide transporter activity.
- Solute-Linked Carrier (SLC) Transporter Inhibition Assays Use biochemical, cell-based or in vivo assays to measure solute-linked carrier transporter activity.
Show all 8 in In Vitro Pharmacology
- Solute-Linked Carrier (SLC) Transporter Substrate Identification Use biochemical, cell-based or in vivo assays to identify solute-linked carrier transporter substrates.
- Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
Testing Services
- Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
-
Germany 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
PortaCellTec (PCT) provides a broad spectrum of hepatic/renal uptake transporter assays (e.g. OATs, OCTs, OATPs) to investigate the inhibitor and substrate characteristics of your drug. As recommended by FDA and EMA we perform in vitro transporter studies with validated drug transporters stably-transfected in HEK-293 cells.
- Website
- www.portacelltec.de
Work with PortaCellTec Biosciences GmbH on Scientist.com
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