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Evotec

Evotec is listed as a large business research supplier in the Scientist.com network, with 11 sites in 5 countries and 4 service areas.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 11

Countries 5

Logo Evotec, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.

Type of company: Large business

Agricultural Sciences Research & Development

Bacteriology PCR and MS-Based Bacterial Identification
Molecular Markers Use of molecular diagnostics to analyze biological markers in the genome and proteome.

Anatomic Pathology

Immunohistochemistry Services Prepare, stain and label with histological and immunological reagents, then evaluate slide preparation of cells or tissue.

Antibodies

Affinity Maturation Use mutagenesis to optimize a complementary determining region and increase antibody affinity.
AlphaLISA Quantification of analytes with high sensitivity, wider dynamic range and no wash steps involved.
Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.

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Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
Antibody Reagents Request information or a price quote for Antibody Reagents services
Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse
Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.
Immunodetection Use antibodies to identify a protein or antigen.
In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Integrated Antibody Development Package-US Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
Pepscan Analysis Screen overlapping peptide sequences to identify linear epitopes.
Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
Recombinant Antibody Fragment Use alternative antibody scaffolds with smaller size, greater stability and higher yields.
Recombinant Antibody Production Request services related to antibody production services.
Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.

Bioimaging

Bioimaging Visualize biological process non-invasively in real time.
Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.
In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.

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Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Ultrasonography diagnostic imaging technique, or therapeutic application of ultrasound.

Show all 1,171 services 1,156 more

Biomarkers

Adipogenesis Assay Detect and quantify intracellular triglyceride accumulation in adipocytes.
Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
Autoantibody Testing Screen for the presence of an autoimmune disorder.
Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.

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Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Bone Resorption Assay Functionally analyze osteoclast activity in vitro.
Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
Complete Blood Count Set of medical laboratory tests that provide information about the cells in blood.
Complete Metabolic Panel Testing Detect electrolyte or glucose imbalance to identify or monitor related disorders.
Creatine Kinase (CK) Testing Detect and monitor pathologies associated with muscle inflammation or damage.
Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
Cytogenetics Examine the structure and function of the cell, especially chromosomes.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
Endocrine Assays Use biochemical, cell based or in vivo assays to measure the concentration of hormones.
Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
Extended Banding Enhance chromosome structures to enable improved screening for abnormalties.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
Focus Forming Assay Use colorimetric or immunofluorescence-based readouts to quantify virions prior to any plaque formation.
Genomics Genomic services including applications to DNA (*sanger sequencing, whole genome amplification, library screening, cloning, sub-cloning, and DNA isolation*) and RNA (*microRNA analysis, RNA isolation, qRT-PCR, mRNA...
HCS Assay Development Requesting services related to HCS assay development.
Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Histamine Release Assay Use in vivo or in vitro assays to measure the release of histamine in response to an allergen stimulation.
Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Human Primary Cell Isolation Isolate primary cells from various human tissues.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
Insulin Autoantibodies (IAA) Testing Detect the risk or presence of type 1 diabetes in early childhood.
Interferon Gamma Release Assay Use in vivo or in vitro assays to measure the cell-mediated immune response to an infectious agent.
Islet Cell Autoantibodies (ICA) Testing Detect Type 1 diabetes-related autoantibodies.
Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
Lipid Peroxidation Assay Use in vitro or in vivo assays to evaluate the effects of oxidative stress on lipid structure and function.
Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Microfluidics-Based Biomarker Isolation and Detection Isolate and detect rare biomarkers in blood samples, such as CTCs, cfDNA, and exosomes.
Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
MultiOmyx Molecular Pathology Tumor Analysis Assess multiple proteins from a single tissue section at a single-cell level.
Multiplex Circulating miRNA Assay Profile miRNAs directly from just 10 μl of crude biofluid or 0.1 ng of purified RNA.
NBE Biomarkers Request information or a price quote for NBE Biomarkers services
Osteoclasts Measure osteoclast activity and bone resorption in human, mouse or rat assays.
Oxidized Low Density Lipoproteins (LDL) Testing Identify the risk for metabolic syndrome and the development of associated diseases.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Peptide Bioanalysis Analyze the structure of Peptides.
Peritoneal Fluid Analysis Determine the cause of fluid accumulation in the peritoneal space.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.
Platelet Function Testing Evaluate complete platelet function in vivo or in vitro.
Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
Proteocarta™ HCP Detect Services Identify and track host cell proteins (HCP) with mass spectrometry for higher sensitivity and coverage.
Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
T Cell Epitope Characterization Evaluate the potency and immunodominance of T-cell epitopes within a molecule.
TUNEL Assay Detect in situ DNA fragmentation.
Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.

Cell Culture and Characterization

3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Bacterial Cell Culture Culture and Grow bacterial cells.
Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
Cell Culture Culture primary or immortalized cell lines.
Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.

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Cell Line Construction Create new recombinant cell lines to exact specifications.
Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.
Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Chromosomal Characterization Establish karyotype/chromosome profile by cytogenetic analysis of cell preparation.
Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Endotoxin Characterization Identify specific molecular structure (e.g., Lipid A profiling), determine bacterial source/strain, and assess biological potency of endotoxins
Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
H & E Services For requesting services related to H&E Services
Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
Insect Tissue Culture Grow insect cells.
Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
Lipofection Transfection of DNA/RNA using lipofection reagents to create lipoplexes.
Microphysiological system (MPS)/organoid analytics microTMA produced from fixed microtissues (MPS)
Microsatellite Instability Analysis Compare allelic profiles and detect genomic instability.
Mycobacterium Screening Detect and distinguish between mycobacterium strains and species.
Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
Resin-based Histology Perform sectioning and histological analysis of epoxy/acrylic/polycarbonate-embedded samples.
RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level
Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Stem Cell Methodologies Study Stem Cell characteristics.
STR Profiling - Microsatellite Short Tandem Repeat Confirm cell line identity and detect cross-contamination.
STR profiling of human and mouse cell lines STR profiling of human and mouse cell lines
Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Chemical and Compound Analysis

Adsorption/Desorption Studies Obtain data on groundwater risk assessment.
Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Bioanalysis Bioanalysis involves the determination of the concentration of test compounds in biological samples including plasma, urine, an...
Chemical Stability Measure the stability of small molecules in solution.

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Chiral Separation Purify therapeutically active isomers of drug candidates.
Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
Compound Integrity Analyze the identity and purity of small molecule drug candidates.
Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Energy Dispersive X-ray Spectroscopy Identify and estimate the elemental composition of a sample based on x-ray emission patterns.
Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
Gas Chromatography Gas chromatography is an analytical technique that separates, identifies, and quantifies compounds in a mixture
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Inductively Coupled Plasma (ICP) Analysis Characterize ultra-small levels of multiple solid analytes simultaneously.
Ion Exchange Chromatography Separate and detect analytes.
Isothermal Titration Calorimetry An ITC assay will be established and optimised for the affinity measurement of test substance to target molecule.
Lipid Nanoparticle (LNP) Characterization Lipid nanoparticle (LNP) characterization is the process of comprehensively analyzing the physical and chemical properties of LNPs and their components to understand their structure, quality, and functionality
Liquid Chromatography Separate substances using a mobile and stationary phase.
Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
Natural Product Libraries Find microbial, botanical and marine sources of natural products.
Natural Product Purification Extract and purify active components of natural products.
NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
Optical Tomographic Imaging Use multiply-scattered light to reconstruct images of illuminated objects.
Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
Photostability Measure drug degradation rates after exposure to various light sources.
Phototoxicity & Photosensitization Test Test the potential for a product to elicit a reaction under UV exposure.
Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
Process Residual Impurities Detection Measure trace levels of impurities.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Small Angle X-Ray Scattering Obtain low-resolution structures of biopolymers in solution using an x-ray beam.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.
Structural Chemistry Examine the relationship between protein structure and function.
Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.
Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Chemical and Compound Testing

USP <2021> Microbial Enumeration Tests Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.
USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.

Chemistry, Manufacturing and Controls (CMC)

Analgesic Active Ingredients Acquire analgesic active ingredients for making over-the-counter medicines.
Analytical Development and Validation Request services related to Analytical Development and Validation
Anticaries Active Ingredients Acquire anticaries active ingredients for making oral health care products.
Antimalarial Active Ingredients Acquire antimalarial active ingredients for making over-the-counter medicines.
API and Drug Product Stability Testing API and Drug Product Stability Testing.
API and Drug Product Storage and Distribution API and Drug Product Storage and Distribution.

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API and drug product storage and release API and drug product storage and release
API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
Bulk Manufacturing Find facilities for large-scale mass production.
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical supply management Clinical supply management
Coating Analysis Evaluate the coat properties of pharmaceuticals, polymers and other finished materials.
Compendial test methods Run Compendial test methods (e.g., KF)
Crystallization studies Crystallization studies
Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
Drug product packaging and labeling Drug product packaging and labelling
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
Formulation Services Assistance when determining the look, texture, fragrance of a product with compatibility with product packaging, knowledge of competitive performance traits and product shelf life.
GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
Hydrogen Deuterium Exchange Mass Spectrometry HDX-MS is a mass spectrometry technique that measures how hydrogen atoms in a protein exchange with deuterium, revealing information about protein structure, dynamics, and interactions. It’s widely used to map binding...
ICH-compliant stability testing Perform ICH-compliant stability testing
Impurities in Drugs Risk Assessment Create a risk-based control strategy to determine any toxic elemental impurities that may be present in human medicines.
IND Enabling Package Request a package of Investigational New Drug (IND) Enabling Studies from our group of trusted suppliers that have enrolled in our IND-Enabling Package Program.
Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Integrated Antibody Development Package-UK Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Integrated Small Molecule Package Process an entire Small Molecule/Compounds Pipeline Project including: Compound Synthesis or Purchase, Compound Analysis/Testing, In Vitro Assays, and Formulation/Reformulation from our bundle of suppliers
Laxative Active Ingredients Acquire laxative active ingredients for making over-the-counter medicines.
Lipoparticle Technology Capture conformationally intact membrane proteins directly from the cell surface using lipoparticle technology.
Menstrual/Diuretic Active Ingredients Acquire menstrual/diuretic active ingredients for making over-the-counter medicines.
Milling, grinding, spray-drying Milling, grinding, spray-drying
Otic Active Ingredients Acquire otic active ingredients for making over-the-counter medicines.
Polymorph Screening Screen for unwanted API forms resulting from the drug formulation process.
Powder Blending Use automatic or semi-automatic powder blending machinery to produce consistent mixes.
Powder Filling Use manual, automatic or semi-automatic machinery to package a variety of powder and granules.
Product Insert Packaging Use product insert or leaflets to inform patients, satisfy regulatory requirements or extend a coupon offer.
Raw Materials & Ingredients Purchase raw materials, ingredients, or chemicals for personal care, cosmetic, consumer health, and beauty products and substances.
Regulatory Starting Materials Sourcing regulatory starting materials (RSM)
Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
Tablet Manufacturing Use automatic or semi-automatic machinery to create various standard and non-standard tablets.
Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Thermo Scientific iCAP Q ICP-MS Expand your analytical capabilities with this complete trace elemental analysis solution for your high-throughput lab.

Clinical Consulting

Bioanalysis Consulting Expert advice to properly and effectively discover, evaluate, and measure chemical or biological materials.
Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Biometrics Consulting Apply statistics and mathematics to drug discovery, clinical trials, and data analysis.
Biostatistics Consulting Apply statistical theory and mathematical principals to research
Clinical Consulting Provide high quality data, on time and within budget, while maintaining the flexibility in delivering personalized services.
Clinical Development Planning Complex document that entails the entire clinical research strategy of a drug, describing the clinical studies that will be carried out for a pharmaceutical entity.

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Clinical Protocol Design & Development Creation of clinical protocol document which details how a clinical trial is designed, relating to to the methodology, hypothesis, and operation of clinical trial to ensure the safety of the patients is...
Clinical Study Reporting (CSR) Report results of clinical trials to regulatory agencies. This includes participant flow, baseline characteristics, outcome measures, statistical analyses, and adverse events.
Clinical Trial Consulting Consulting services for Clinical trials.
Clinical Trial Disclosure and Reporting (CTDR) Clinical Trial Disclosure and Reporting (CTDR) is the mandatory process of registering clinical trials and making their methodology and results publicly available to ensure transparency, reduce publication bias...
Clinical Trial Feasibility Request services related to Clinical Trial Design and feasibility.
Clinical Trial Recruitment Recruitment, enrollment and retention of patients for clinical trials.
Data & Risk Management Determine the extent of the risk and the reliability of the data used to access the aforementioned risk.
IND Writing Consulting Consulting for an Investigational New Drug Application
Pharmacovigilance Oversight Pharmacovigilanve oversight encourages the proposal of a structure for a pharmacovigilance plan and a safety specification that summarizes the identified and potential risks of the product to be addressed...
Regulatory Compliance & Documentation Regulatory compliance describes the goal that organizations aspire to achieve in their efforts to ensure that they are aware of and take steps to comply with relevant laws, policies, and regulations.

Clinical Trials

Bayesian Adaptive Trial Design Bayesian adaptive trial design allows real-time adjustments to clinical trials based on ongoing data analysis, enhancing flexibility and efficiency.
Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
Case Report Monitoring & Auditing Ensure the adequate collection and traceability of clinical data in preparation for review by the FDA.
Central Institutional Review Board Services Ensure the safety and protection of human subjects participating in a study.
Clinical Biostatistical Services Analyze and interpret data throughout all phases of clinical trial development.
Clinical Project Management Management of clinical trial sites, as monitored by various clinical monitoring organizations. Ensure that the clinical trial is being performed according to the correct protocol to uphold the validity of the data...

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Clinical Trial Design Develop study-related protocols, case report forms (CRFs) and database tools for records management.
Clinical Trial Risk Management Plan that maintains treatment quality throughout lifecycle and improve decision making.
eCOA - Electronic Clinical Outcomes Assessments Use smartphones, computers and tablets to allow patients to directly report health outcomes.
EHR to EDC Transfer data from an Electronic Health Record (EHR) system to an Electronic Data Capture (EDC) system, which is commonly used in clinical trials
EHR to EDC- Electronic Health Record to Electronic Data Capture Electronic Health Record to Electronic Data Capture
ePRO - Electronic Patient-reported Outcome Patient reported outcome collected by electronic methods.
Informed Consent Development Informed Consent is a prerequisite of any conduct within a clinical trial, and refers to the process in which the permission of the potential clinical trial subject is obtained. Informed consent applies to all...
Investigator Meeting Planning & Execution Investigator planning and meetings ensure that there is proper communication and reliability during a clinical trial. Allows for efficient work flow.
IP Labeling Proper IP labeling guidelines are produced by the Food and Drug Association. Based on the compound or product in need of proper labelling there are guidelines that can be followed.
IP Packaging Proper packaging of pharmaceutical products and goods is crucial to ensure the validity and quality of the product being supplied. Proper investigational product packaging is aided by the use of quality...
Mass Balance Studies Design a study to determine the mass balance of drug-related material occurring administration of dose, the ratio of parent drug metabolite(s) in circulation, and the primary route of excretion of drug-related material.
Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Phase 1-3 Studies Design phase 1-3 studies that seek to identify if a drug is safe, effective, and more efficient than other available treatments on the market.
Recruiting Healthy Volunteers Recruit volunteers who have no known significant health problems, and is willing and consenting to participate in research to test a new drug, device, or intervention.
Regulatory Affairs Consulting Receive assistance ensuring compliance with regulatory requirements.
Regulatory Operations Ensure that all specific regulatory documents are published and properly organized before submission. 
Sample Management Find providers who offer process of handling, organizing, and tracking samples in a lab
Site Monitoring Maintain oversight over participant's health during a clinical trial.
Site/Patient Payments Allow for different suppliers to organize the proper patient and site payments for a clinical trial. Provides real-time payments, reduce workloads for site staff and minimize the amount of time participants spend...
Statistical Analysis Planning Technical and detailed elaboration of the principal features of the analysis described in the protocol, and includes detailed procedures for executing the statistical analysis of the primary and secondary variables...

Companion Diagnostics

Pancreatic Cancer CDx Design and validate companion diagnostics for pancreatic cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Rheumatoid Arthritis (RA) CDx Design and validate companion diagnostics for RA that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.

Creative

Case Studies Recruit research participants with a behavioral condition to receive either an investigational behavioral intervention or a behavioral intervention in clinical use.

Data Science/Bioinformatics

Biostatistical Design Use statistics to ensure appropriate pre-clinical and clinical study design.
Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Clinical Companion Diagnostics Analysis The process of finding patients who are likely to respond positively to a drug and designing a diagnostic tool to identify this group of patients before or with a therapy.
Clinical Data Analysis Analysis that helps you make sense of your clinical data
Clinical Data Management A process that includes acquiring, validating, storing, protecting, and processing required data to ensure the accessibility, reliability, and timeliness of the data.
Clinical Data Science and Modeling A process that helps make sense of your clinical data

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Clinical In Silico Drug Dynamics The process to understand drug dynamics by computer analysis and simulation.
Clinical In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your omics data
Clinical Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects
Clinical Responder Analysis, Patient Stratification The process of identifying patients that are more likely to respond positively to a drug.
Clinical Software Tools Software designed to serve the needs of clinical research groups.
Clinical Trial Integration Analysis The process of combining data from multiple clinical trials to understand categories of drugs and drug behavior in a more global way.
Discovery Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.
Discovery Biomarker Analytics An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Discovery Compound Screening Analytics Screening of an entire compound library directly against the drug target or in a more complex assay.
Discovery Data Analysis Analysis that helps you make sense of your discovery data
Discovery Data Integration The process of combining different complex data types together to make it easier to understand or analyze.
Discovery Data Science and Modeling A process that helps make sense of your discovery data
Discovery Databases Databases specifically designed for drug discovery use.
Discovery In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your Genomics/Transcriptomics data
Discovery In Silico Proteome Analysis Used to understand the global protein environment, specifically drug-protein interactions.
Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Discovery Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
Discovery Predictive Analytics Analytical approaches to predict how a drug target behaves in a given environment.
Discovery Software Tools Software designed to serve the needs of discovery research groups.
Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
Microsatellite Analysis for Normal Tumor Instability (MANTIS) Classify samples by MSI status utilizing NGS data.
Proteome Data Analysis Find tools for analysis of homology and similarity, protein function and structural properties.
RWE/HEOR Data Management A process that includes acquiring, validating, storing, protecting, and processing required data to ensure the accessibility, reliability, and timeliness of the data.
RWE/HEOR Data Science and Modeling A process that helps make sense of your clinical data
RWE/HEOR Drug Response Analysis A process to understand how a population is responding to a drug, specifically if there are any adverse events.
RWE/HEOR Drug/Therapy Discontinuation Analysis An analysis to understand patient behavior. Are the drugs taken on time, do the patients discontinue use, and if so how long after starting, etc.
RWE/HEOR Machine Learning/AI Complex analytical approaches to find patterns and make predictions in RWE/HEOR projects
Translational Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.
Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
Translational Data Analysis Analysis that helps you make sense of your translational data
Translational Data Curation Generally, human curation of acquired data to assess the quality and reliability of different data.
Translational Data Harmonization and Integration Process to combine different data together for better understanding and analysis of the integrated data.
Translational Data Knowledge Extraction Analytical approaches to extract data from different sources like publications, databases, etc. 
Translational Data Management A process that includes acquiring, validating, storing, protecting, and processing required data to ensure the accessibility, reliability, and timeliness of the data.
Translational Data Science and Modeling A process that helps make sense of your translational data
Translational In Silico Genomics/Transcriptomics Data Analysis A process that helps make sense of your omics data
Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Translational Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
Translational Software tools Software designed to serve the needs of translational research groups.

Developmental and Reproductive Toxicology (DART)

Juvenile Toxicity Study - Rat Conduct a study to determine the differences in toxicity between immature and mature systems in rats.

Discovery Chemistry

Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
Bioactive Research Tools Find bioactive peptides, bioactive lipids, bioactive materials like glass, paper, and polymers and nanotechnology.
Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
Certified Standards Find certified standards for assays, tests and services.
Chiral Synthesis Synthesize a compound by a method that favors formation of a specific enantiomer or diastereomer.
Compound Docking Identify potential compound hits based on the 3D structure of a target protein.

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Compound Finding Service Enter the compound name, CAS # or SMILES string in the box below or upload an Excel, Word or SD file with a list of compounds.
Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
Compound Purchase Buy compounds, building blocks or compound libraries.
Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Custom Libraries Find or synthesize mg to kg amounts of target-specific and target-agnostic compounds for HTS and biological profiling.
Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Discovery Molecular Modeling and Simulation Analytics Computational methods to model and study the behavior of molecules, from small chemical systems to large biological molecules.
DNA Encoded Library (DEL) capabilities The rapid screening of vast chemical libraries by encoding millions of small molecules with unique DNA sequences, facilitating the identification of potential drug candidates.
Extractable and Leachable Assessment Quantify potential impurities from container closures & packaging.
Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Leachable and extractable testing Leachable and extractable testing
Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Natural Product Screening Screen large natural product collections for therapeutic activity.
Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
Polyethylene Glycols (PEGS) Acquire polyethylene glycols (PEGS) to use as ingredients in consumer healthcare products.
QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
Trace Elemental Analysis Identify organic and inorganic elements in foods and dietary supplements at ppm to sub-ppt levels.
Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Disease Models

Acute Kidney Failure Models Measure therapeutic endpoints in animal models of acute kidney failure.
Acute Liver Failure Models Measure therapeutic endpoints in animal models of acute liver failure.
Acute Lung Injury Models Measure therapeutic endpoints in animal models of acute lung injury.
Alzheimer's Disease Models Measure therapeutic endpoints in animal models of Alzheimer's disease.
Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.

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Auto-immune Hepatitis Models Measure therapeutic endpoints in animal models with auto-immune hepatitis.
Autoimmune Models Measure therapeutic endpoints in animal models with autoimmune disorders.
Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
Cognition Models Measure therapeutic endpoints in animal models of cognition.
Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
Cough Models Test the therapeutic efficacy of drug candidates in cough models.
Critical Care Models Diagnose and manage life-threatening conditions requiring sophisticated organ support and invasive monitoring.
Demyelination Models Measure therapeutic endpoints in animal models with demyelination pathology.
Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
Disease Simulation Modeling Disease Simulation Modeling
Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
Electroencephalogram EEG Models Record electrical activity along the scalp of animal models or human patients.
Endometriosis Models Measure therapeutic endpoints in animal models of endometriosis.
Excitotoxicity Models Measure therapeutic endpoints in animal models with excitotoxic pathology.
Fecal Microbiota Transplantation (FMT) - Mouse Use germ-free mice to evaluate the properties of complex or defined gut microbiota following fecal microbiota transplantation (FMT). Axenic (germ-free) mice transplanted with donor microbiota can be utilized to assess...
General Pain Models Measure therapeutic endpoints in animal models of general pain.
Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
IGA Glomerulonephritis Models Measure therapeutic endpoints in animal models of IgA glomerulonephritis.
In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
Malaria Models Measure therapeutic endpoints in animal models of malaria.
Microdialysis Models Measure the effect of drug candidates on neurotransmission in rat or mouse models.
Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
Myelination Models Measure therapeutic endpoints in animal models with induced myelination, remyelination or developmental myelination.
Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
Pain Models Test therapeutic efficacy of drug candidate in pain model.
Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
Precision Cut Lung Slices (PCLS) Use a phenotypically accurate model of lung behavior for screening and target validation.
Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
Receptor Occupancy Models Determine the effective dose and concentration needed to reach effective levels in a given tissue.
Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
Schizophrenia Models Measure therapeutic endpoints in animal models of schizophrenia.
Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
SHR/NCrl Rat Use a single animal species to create one or more disease models fior hematopoesis.
Sleep and Circadian Biology Systems to collect and analyze data related to sleep and circadian rhythms
Spinal Cord Injury Models Measure therapeutic endpoints in models of spinal cord injury.
Stroke Models Measure therapeutic endpoints in animal models of stroke.
Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
Video Behavior Monitoring Systems to collect continuous video for use in behavioral research
Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.
Visceral Pain Models Measure therapeutic endpoints in animal models of visceral pain.
Weanling Rat Use a single animal species to create one or more disease models for anemia.
Xenografts Evaluate drug candidate in tissue graft or organ transplant model.

DNA & RNA

Amplified Fragment Length Polymorphism Detection Detect DNA polymorphisms based upon restriction enzyme digestion and PCR.
ATAC-seq ATAC-seq
Bisulfite Sequencing (RRBS) Analyze genome-wide methylation profiles on a single nucleotide level.
Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
Cell Free DNA Assay Detect known mutations and discover new ones in cell-free plasma DNA.

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ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
Chromatin Interaction Analysis-Paired End Tag Sequencing Sequence DNA using Chromatin Conformation Capture (3C) together with Chromatin Immunoprecipitation (ChIP).
Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
De Novo Genome Sequencing Determine the DNA sequence of uncharacterized genomes.
De Novo Transcriptome Sequencing Identify new genes without the need for a reference genome sequence.
Digital Polymerase Chain Reaction Obtain improved absolute target quantification and rare allele detection compared to conventional qPCR.
DNA Extraction Extract DNA from an original source.
DNA Fragmentation DNA fragmentation is the physical breaking of a DNA molecule into smaller pieces
DNA Library Screening Screen genomic or cDNA libraries for positive clones.
DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
DNA Sequencing Determine the nucleotide sequence of DNA samples.
DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
DTG-Seq™ Evaluate the efficiency and distribution of CRISPR mutations at on-target sites.
Exome Sequencing Determine protein-coding nucleotide sequences in a DNA sample.
Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
Genomic DNA cloning Clone and propagate genomic DNA inserts of 5-50kb.
Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
Genotyping Examine a DNA sequence to identify specific genetic varients .
HCR™ RNA-FISH Detect and visualize RNA expression in situ
In Situ Hybridization Localize specific nucleic acid targets using labeled complementary probes.
Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
Metagenomic Sequencing Sequence genetic material recovered directly from environmental samples
miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
Multiplex Cellular miRNA Assay Use Firefly™ technology for multiplex cellular microRNA profiling.
NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
Oligonucleotide Synthesis The chemical process of creating custom, short fragments of nucleic acids (DNA or RNA)
Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
Poly (A) tail Length Profiling (PAL-Seq) Conduct high-throughput sequencing of individual mRNA poly (A) tails.
qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
RAD Sequencing Examine a small percentage of the target genome.
RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
RNA Extraction Isolate total RNA or mRNA from cells or tissues
RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
RNAi Pathway Analysis Use high-throughput RNAi genetic screens to elucidate relevant signaling pathways.
RNAscope In Situ Assays Profile single-cell gene expression in situ.
RNAseq and DNAseq library preparation and sequencing DNA/RNA sequencing and preparations
Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.
shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
siRNA Synthesis Produce high quality siRNAs for gene silencing studies.
SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
Spatial Transcriptomics Determine the sub-cellular localization of mRNA molecules. Use this to identify cellular heterogeneity in tissues, tumors, immune cells and the subcellular distribution of transcripts.
Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Targeted Sequencing/Resequencing Detect variations in a genome subset.
TCR Repertoire Sequencing Analyze the T cell receptor repertoire by means of next-generation sequencing.
Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.
Whole Genome Bisulphite Seq Profile genome-wide DNA methylation.
Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
Whole Genome Sequencing Determine the entire genetic make-up of an organism.

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
Chemoinformatics Consulting The use of computer and informational techniques applied to a range of problems in the field of chemistry.
Consulting Services Work with consultants who provide expert advice in various areas of research and technology.
Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
Pathophysiology Consulting Request services related to Pathophysiology Consulting

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Pharmacogenetics Consulting Access genomic services required for clinical trials, such as genotyping, genetic variation testing and DNA isolation.
Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.
Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.
Toxicology Consulting Use models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

Effectiveness

Antimicrobial Pharmacodynamics Ascertain the effectiveness of an antimicrobial compound and test levels of antibiotic resistance against specific bacterial pathogens.
Bioequivalence Studies for Veterinary Drugs Assess the expected biological equivalence of two proprietary preparations of a veterinary drug.
In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
Laboratory Dose Confirmation Studies Conduct in vivo studies to confirm the effectiveness of a selected drug dose in the lab.
Laboratory Dose Determination Studies Compare the effectiveness of three non-zero therapeutic concentrations for various durations to a non-medicated control group, and a non-medicated uninfected control group.
Minimum Bactericidal Concentration (MBC) Test Assess the bactericidal activity of a test compound.

Food Safety & Regulations

Water Activity Determine water activity in consumer healthcare products involving a USP or FCC monograph.

General in vivo Toxicology

Dose Range Finding Study - Dog /Canine Conduct a study to determine the dose range of your compound in dogs/canines.
Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
Dose Range Finding Study - Other Species Conduct a study to determine the dose range of your compound in other species.
Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
Effective Dose (ED), 50% Toxicity Test Quantify the diluted toxin needed to induce sub-lethal effects upon constant exposure in half of test organisms.
General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

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IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Nonclinical Study Management Provide nonclinical study management services to pharmaceutical and biotech companies. The services can be customized to meet the clients needs.
Nonclinical Study Monitoring Provide nonclinical study monitors throughout the US and Canada to monitor in vivo and in vitro studies are CROs
Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
Repeat Dose Toxicity Study - Dog / Canine Conduct a repeat dose study in dogs to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Monkey / Non-human Primate Conduct a repeat dose study in monkey/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Rat Conduct a repeat dose study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.
Single Dose Acute Toxicity Study - Dog / Canine Conduct a single dose study in Dogs and Canines to determine the toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Monkey / Non-human Primate Conduct a single dose study in Monkeys and Non-human Primates to determine the toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.
Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

Human Biological Samples

3D InSight™ Liver Microtissues Perform in vitro assessment of islet function for efficacy and toxicity testing.
Cell Line and Cellular Services Promotion for Cells and Cell lines
Custom FFPE cell line blocks Custom IHC compatible FFPE cell line blocks and sections
Custom PDX models For requesting Custom PDX models
Existing PDX models For requesting Existing PDX models
HBS Alzheimer's Acquire fresh, frozen, or fixed Alzheimer's tissues or other related Alzheimer's HBS.

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HBS Amyotrophic Lateral Sclerosis (ALS) For requesting HBS Amyotrophic Lateral Sclerosis (ALS).
HBS Asthma For requesting HBS Asthma.
HBS Autoimmune Diseases For requesting Autoimmune Diseases HBS.
HBS Bacterial Infections Provision of HBS Bacterial Infections samples
HBS Cardiovascular Disease Request tissue samples and Bio-specimen samples from patients with Cardiovascular Disease
HBS Chronic Obstructive Pulmonary Disease (COPD) Acquire fresh, frozen, or fixed COPD tissue or for requesting other COPD human biospecimen samples.
HBS Diabetes For requesting HBS Diabetes.
HBS Fungal Infections Provision of HBS Fungal Infections samples
HBS Genetic Diseases For requesting Genetic Diseases HBS
HBS Healthy/Controls For requesting HBS Healthy/Controls
HBS Huntington's For requesting HBS Huntington's.
HBS Kidney Disease Request samples from patients with Kidney Disease
HBS Leukemia For requesting HBS Leukemia
HBS Liver Disease Request samples from patients with Liver Disease.
HBS NASH For requesting HBS NASH
HBS Neurological Diseases For requesting Neurological Diseases HBS
HBS NSCLC For requesting HBS NSCLC
HBS Oncology For requesting Human biospecimens from Oncology indications
HBS Parkinson's For requesting HBS Parkinson's
HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
Human 3D cultures Provision of 3D culture of Human Primary Cells
Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
Human Amniotic Fluid Acquire fresh/frozen normal amniotic fluid based on patient demographics and history.
Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
Human Biopsy Cell Models Request human biopsy cell models.
Human Blood Acquire fresh/frozen human blood based on patient demographics, disease stage, history and treatment.
Human Blood by-products For requesting Human Blood By-products
Human Bone Marrow Aspirates Acquire fresh/frozen Bone Marrow mononuclear cells based on patient demographics, disease stage, treatment and history.
Human Bone Marrow Cells Acquire fresh, frozen, or fixed normal bone marrow based on patient demographics and history.
Human Buffy Coats Acquire fresh/frozen Buffy Coats based on patient demographics, disease stage, treatment and history.
Human Cell Lysates For requesting human Cell lysates.
Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc
Human Cerebral Spinal Fluid (CSF) Acquire fresh/frozen normal cerebrospinal fluid based on patient demographics and history.
Human DNA Acquire human DNA.
Human DNA & RNA Acquire fresh/frozen Human DNA & RNA based on patient demographics, disease stage, treatment and history
Human Exosomes Request services related to the creation and development of human exosomes
Human Fecal Matter Acquire fresh/frozen normal feces based on patient demographics and history.
Human Fixed Tissue Acquire Human fixed tissue based on patient demographics, disease stage, history and treatment.
Human Fresh Tissue For requesting fresh human tissue
Human Frozen Tissue For requesting frozen human tissue.
Human HSC's For requesting human sourced hematopoetic stem cells
Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
Human iPSC's For requesting human sourced induced pluripotent stem cells.
Human Leukopaks Obtain enriched leukapheresis-derived products from normal peripheral blood.
Human Melanocytes Human Melanocytes are pigment-producing cells primarily found in the skin, hair follicles, and eyes
Human MSC's For requesting human sourced mesenchymal stem cells.
Human Nasal Fluid Acquire fresh/frozen normal nasal fluid based on patient demographics and history.
Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...
Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
Human Plasma Acquire fresh/frozen human plasma
Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
Human Red Blood Cells Acquire fresh/frozen normal red blood cells based on patient demographics and history.
Human RNA Acquire fresh/frozen Human RNA based on patient demographics, disease stage, treatment and history.
Human Saliva Acquire fresh/frozen normal saliva based on patient demographics and history.
Human Semen Acquire fresh/frozen normal semen based on patient demographics and history.
Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.
Human Sputum Acquire fresh/frozen normal sputum based on patient demographics and history.
Human Synovial Fluid Acquire fresh/frozen normal synovial fluid based on patient demographics and history.
Human Tears Acquire fresh/frozen Tears based on patient demographics, disease stage, treatment and history.
Human Umbilical Cord Blood For requesting Human Umbilical Cord Blood.
Human Urine Acquire fresh/frozen normal urine based on patient demographics and history.
Human Vaginal Fluid/ Swab Acquire fresh/frozen normal vaginal fluid based on patient demographics and history.
Human Whole Blood Acquire fresh/frozen normal whole blood based on patient demographics and history.
Human Whole Blood For requesting Human Whole Blood
Human Whole Organs Procure non-transplantable whole human organs or tissues, healthy or diseased, for medical research and development.

In Vitro ADME

Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
Cell Fractionation Isolate organelles and subcellular components.
Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.

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CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
GI Fluid Stability Determine dosing and turnover of drug candidates in gastrointestinal fluids.
HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
In Vitro ADME in Vitro ADME services
Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.
Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
Multidrug Resistance Identify potential causes of drug-drug interactions.
No Label Methods Use mass spectrometry to detect and identify non-radiolabeled drug intermediates in pre-clinical samples.
Non Isotopic Labeling Track unlabeled macromolecules through a metabolic pathway or cell.
Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
Radiolabeled Tracers Use radiolabeled drug metabolites as radiotracers for measuring desired physiological processes.
Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
Reference Standards Find reference standards for assays, tests and services.

In Vitro Assays

3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
Antivirals Measure anti-viral activity in biochemical and cell assays.
Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Apoptotic Cell Staining Detect apoptotic cells in culture.
Assay Development Construct or create new assays or modify existing ones.

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Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Cell Cycle Assays Measure cell cycle markers and the molecular events that control cell cycle progression.
Cell Painting Cell painting is multiplexed image-based assay used to investigate subtle changes in cellular homeostasis
Cell Proliferation Measure cell number, cell viability and cell division.
Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
Dengue Virus Assay A dengue virus assay is a laboratory test used to detect, confirm, or quantify a dengue infection or previous exposure
ELISpot Assay and Testing Detect low levels of antigens.
Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
Epigenetic Profiling In Vitro Assays Test for epigenetic modifications and indicator levels via in vitro assays.
Epstein-Barr Virus Assay Detect EBV antibodies or viral DNA
Fully Automated Assays Develop and perform assays that require no manual steps
Glucose Release Assay Determine free glucose levels in biological samples.
Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.
Glycobiology Study the structure biosynthesis and biology of carbohydrates
Hepatitis D Virus Assay A Hepatitis D Virus (HDV) assay is a laboratory blood test used to detect HDV infection.
Herpes Simplex Virus Assay Detect and identify HSV infections.
High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
HTS Assay Development Develop assays to use in high throughput screening.
Human Immuno-deficiency Virus Infection CDx Design and validate companion diagnostics for HIV infection that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
ImmunoSEQ Assay Unmask the identity of millions of T- and B-cell receptors in a single sample using bias-controlled multiplex PCR amplification, high-throughput sequencing, and sophisticated bioinformatics.
In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Human Cell Assays Request in vitro human cells for assays
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Influenza Virus Assay Detect, quantify, or evaluate the virus, its antigens, or the antibodies it produces
Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
Lipolysis Measure the hydrolysis of triglycerides into glycerol and free fatty acids.
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
Microbiology Study microbes and their role in human health.
Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
OnTarget™ ctDNA Analysis Detect and monitor circulating tumor DNA in blood with OnTarget™ enrichment technology.
Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
Reporter Virus Particles (RVPs) - Dengue Neutralization Assay Use Dengue Reporter Virus Particles to measure neutralizing antibodies against each of the four Dengue serotypes.
SARS-CoV-2 (COVID-19) Assays Search for Available SARS-CoV-2 Assays
Serine Protease Assay Detect apoptosis by measuring protease activity.
Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.
Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
ATP Competitive Study Determine whether or not a compound is competitive with ATP.
B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Assays Use biochemical, cell based or in vivo assays to measure CTLA-4 receptor activity.

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Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
Extracellular signal Regulated Kinase Assays Use biochemical, cell based or in vivo assays to measure ERK enzyme activity.
Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
Histone Acetyltransferase (HAT) Assays Use biochemical, cell-based or in vivo assays to measure histone acetyltransferase activity.
Histone Deacetylase (HDAC) Assays Use biochemical, cell-based or in vivo assays to measure histone deacetylase activity.
HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
Human BCL Assays Use biochemical, cell-based or in vivo assays to measure BCL activity.
Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
In Vitro Excitotoxicity Models Use in vitro models to measure therapeutic endpoints associated with excitotoxic pathology.
In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
In Vitro Fertilization Models Measure oocyte maturation, embryo development in culture and sperm fertilizing ability.
In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.
In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vitro Oncology Models Use cell-based and biochemical models of cancer.
Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Liposome Immunoassay Use immuno-liposomes for improved signal intensity and detection sensitivity compared to enzyme and fluorescent immunoassays.
Mammalian Target of Rapamycin Complex Assays Use biochemical, cell based or in vivo assays to measure mTORC enzyme activity.
Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
Mitogen/Extracellular signal-regulated Kinase (MEK) Assays Use biochemical, cell based or in vivo assays to measure MEK enzyme activity.
Mutant B-Raf Assays Use biochemical, cell based or in vivo assays to measure mutant B-Raf enzyme activity.
Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
PARP Assays Use biochemical, cell-based or in vivo assays to measure PARP activity.
Peptide Transporter Assays Use biochemical, cell-based or in vivo assays to measure peptide transporter activity.
Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
Phosphatidylinositol 3-Kinase (PI3K) Assays Use biochemical, cell based or in vivo assays to measure PI3K enzyme activity.
Phosphodiesterase Assays Measure phosphodiesterase activity in biochemical and cell-based assays.
Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.
Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
Programmed Death-Ligand 2 (PD-L2) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of PD-L2 ligand.
Protease Assay Measure protease activity in biochemical and cell-based assays.
Protein Kinase B (Akt) Assays Use biochemical, cell based or in vivo assays to measure Akt enzyme activity.
Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Protein/Enzyme Targets For requesting Protein/Enzyme Targets
Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
RAS Assays Use biochemical, cell based or in vivo assays to measure RAS enzyme activity.
Reversibility Study Determine whether or not a compound inhibits an enzyme reversibly.
Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
Solute-Linked Carrier (SLC) Transporter Inhibition Assays Use biochemical, cell-based or in vivo assays to measure solute-linked carrier transporter activity.
Solute-Linked Carrier (SLC) Transporter Substrate Identification Use biochemical, cell-based or in vivo assays to identify solute-linked carrier transporter substrates.
Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
Target Characterization Characterize potential drug targets during the drug discovery process.
Target Identification Identify the target(s) of a biologically active substance.
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.
UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.
Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.
Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.

In Vitro Toxicology

ADCC and CDC Assay Services Measure toxicity of antibodies.
Cardiac Channels Measure the arrhythmia producing potential of test compounds.
Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
Cytotoxicity Test for effects on cell viability and proliferation

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Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
Genotoxicity Evaluate potential of a compound to cause mutations and chromosomal aberations
Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
HepaRG Cells Obtain terminally differentiated and cryopreserved hepatic cells that retain many characteristics of primary human hepatocytes.
Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
Short Time Exposure (STE) Test Use in vitro eye irritation tests to assess cytotoxicity in SIRC cells (rabbit corneal cell line).
Toxicology- in vitro Toxicity testing and model development in vitro on developmental and adult neurotoxicity
Tubule Epithelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the kidney.

In Vivo ADME

Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
Chronic Bile Duct Cannulation (BDC) Study - Dog / Canine Conduct a bile duct cannulation (BDC) study in dogs/canines to support the absorption, distribution, metabolism and excretion profiling of your compound.
Chronic Bile Duct Cannulation (BDC) Study - Other Species Conduct a bile duct cannulation (BDC) study in other species to support the absorption, distribution, metabolism and excretion profiling of your compound.
Chronic Bile Duct Cannulation (BDC) Study - Rat Conduct a bile duct cannulation (BDC) study in rats to support the absorption, distribution, metabolism and excretion profiling of your compound.
In Vivo Radiolabeled Metabolism Determine the qualitative and quantitative metabolism and/or degradation of an active ingredient in animals.
Mass Balance Study - Dog / Canine Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in dogs/canines.

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Mass Balance Study - Monkey / Non-human Primate Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in monkeys/non-human primates.
Mass Balance Study - Other Species Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in other species.
Mass Balance Study - Rat Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in rats.
Milk Secretion Study - Rat Conduct a study to determine the extent of milk secretion of your radioactive compound in rats.
Ocular Distribution Study - Other Species Conduct a study to determine the distribution of your compound in ocular tissues of other species.
Ocular Distribution Study - Rabbit Conduct a study to determine the distribution of your compound in ocular tissues of the rabbit.
Ocular Distribution Study - Rat Conduct a study to determine the distribution of your compound in ocular tissues of the rat.
Qualitative Whole Body Autoradiography Request information or a price quote for Qualitative WBA services
Quantitative Whole Body Autoradiography (QWBA) Determine the tissue distribution of a radiolabeled compound in Rodent and Non-Rodent Species.
Quantitative Whole Body Autoradiography (QWBA) - Non-rodent Species Conduct a study to determine the tissue distribution of your compound radiolabeled compound in non-rodent species.
Quantitative Whole Body Autoradiography (QWBA) - Rodent Species (Mouse, Rat) Conduct a study to determine the tissue distribution of your compound radiolabeled compound in rodent species.
Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.

In Vivo Pharmacokinetics

In Vivo Immunogenicity Study An in vivo immunogenicity study evaluates a substance's ability to trigger an immune response within a living organism.
In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
Integrated In Vivo Services Package Process an entire In Vivo Project including: Dose Formulation, PK Screening, ADME-Profiling, Toxicology, Safety Pharmacology, DART, IND Filing from our bundle of suppliers.
Mass Balance Elucidate excretory pathways and organ distribution of a parent drug and metabolites
Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).

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Mouse Efficacy Monotherapy Use mouse models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Ocular Pharmacokinetic (PK) Screening - Dog / Canine Conduct a pharmacokinetic screening study in dogs/canines that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Other Species Conduct a pharmacokinetic screening study in other species that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Rabbit Conduct a pharmacokinetic screening study in rabbits that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Ocular Pharmacokinetic (PK) Screening - Rat Conduct a pharmacokinetic screening study in rats that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Pharmacokinetic (PK) Screening - Dog / Canine Run pharmacokinetic studies in dogs that measure a drug’s absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound.
Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Lab Supplies, Facilities, and Equipment

Biobanking Store and track biological samples.

Medical Communications

Abstracts Request services related to the writing and review of abstracts
Case Reviews Review medical cases from Clinical Trials.
Consensus reports Develop and submit a report that is a comprehensive examination by an expert panel of a scientific or medical issue.
Data Visualization Visualize data collected from clinical trials and/or clinical research.
Investigational Medicinal Product Dossier (IMPD) and Investigational New Drug (IND) Dossier Develop and submit Investigational Medicinal Product Dossier (IMPD) and Investigational New Drug (IND) Dossier
Medical Literature Reviews Systematic searching, appraisal, and synthesis of published scientific literature to generate evidence-based reports on a specific topic, disease, or treatment.

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Medical Publications Make clear and accurate presentations of scientific and technical data.
Patient Narratives Compliant collection and use of individual patient stories to illustrate the impact of a disease or treatment, often for training or empathy-building purposes.
Pharmacodynamic/ Pharmacokinetic Reports Create Pharmacodynamic/ Pharmacokinetic reports to report to the appropriate regulatory bodies.
Poster Design and Development Design and Develop Posters for Poster Symposiums and conferences to effectively convey science information.
Protocol and Study Reports Write protocol and study reports, specifically relating to the drafting, writing, and editing of Clinical Safety Reports.
Publication Writing Create further publication documents. Investigational device exemptions (IDEs) BLAs, MAA, PMA, eCTDs, informed consents, CMC and manufacturing reports, orphan drug designations (ODD), briefing books.
Quality Control/ Quality Assurance Documents Develop quality control or quality assurance documents.
Regulatory Audit Supports Providing documentation, responses, and expert assistance to ensure preparedness and successful outcomes during inspections by regulatory bodies.
Regulatory Submissions and Compliance Draft, format, and submit documents to Pharmaceutical approval agencies according to documentation and guidelines. This includes documents such as NDAs, INDs, SUSARs, AE reporting, RMPs, and PSURS.
Review Article/ Submission Drafting and managing the process of submitting an objective, comprehensive summary of the current literature on a disease or treatment area to a peer-reviewed journal.
Target Product Profile (TPP) A sponsor prepared document which summarizes the drug development program that is described in terms of the labelling concepts. This profile is a communication method used between the FDA and sponsor which can be used...
Toxicology Reports Create pre-clinical toxicology reports.

Model Development

Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Animal Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study animal lung behavior.
Human Precision-Cut Liver Slice Model Acquire a fresh phenotypically-accurate model to study human liver behavior.
Human Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study human lung behavior.
In Silico PK-PD Modeling Quantitative modeling and simulations correlation of pharmacokinetic and pharmacodynamic endpoints in support of preclinical and clinical development.
Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.

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Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
NMRI Mouse Use a single animal species to create one or more disease models for cachexia and hemophilia.
Non-Human Primate Models Use a single animal species to create one or more disease models.
PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
Pre-clinical Animal Surgery Conduct surgey in animals used as pre-clinical models.
SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Zucker Rat Use a single animal species to create one or more disease models for cachexia.

Nanotechnology

Custom Nanostructures Fabricate materials in the form of spherical particles, nano-tubes, wires, rods, discs, flakes, prisms or dispersions.
Drug Delivery Technology Create microstructures that enhance drug metabolism properties.
Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.
Nanoparticle Conjugation and Functionalization Modify biomolecules to enhance structure and function.

Neurotoxicology

Single Dose Acute Neurotoxicity Study - Other Species Conduct a single dose study in other species to determine the neurotoxicty of your compound.
Single Dose Acute Neurotoxicity Study - Rat Conduct a single dose study in rats to determine the neurotoxicty of your compound.

Non-Human Biospecimen

Dog / Canine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Dog / Canine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Dog / Canine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Guinea Pig Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Guinea Pig Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Guinea Pig Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.

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Monkey / Non-Human Primate / NHP Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Monkey / Non-Human Primate / NHP Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Monkey / Non-Human Primate / NHP Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Mouse Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Pig / Minipig / Porcine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Pig / Minipig / Porcine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Pig / Minipig / Porcine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Rabbit Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Rabbit Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Rabbit Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Rat Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Rat Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Rat Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.

Oncology Models

Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
CAR-T Efficacy In Vivo assessment of CAR-T and CAR-NK efficacy in a humanized mouse
Endocrine System Xenograft Xenografts derived from organs and glands of the Endocrine system. This include samples from the Pituitary Gland, Thyroid, and Adrenals.
Experimental Metastatic Models Measure therapeutic endpoints in animal models of experimental metastatic cancer.
Immuno-PDX Utilize the patient-derived xenograft for drug response profiling and biomarker discovery of immuno-oncology drug candidates.

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Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
NCG Model Study tumor biology and immuno-oncology in the CRISPR/Cas9-generated immunodeficient mouse model.
Nervous System Xenografts Xenografts relating to the Nervous system. This includes samples from the Head, Neck, Brain, and Nerves.
Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Oncology Xenografts Xenografts derived from oncological samples.
Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
Urinary System Xenografts Xenografts derived from organs of the Urinary system. This includes, but is not limited to, xenografts from the Bladder, Kidney, and Urethra.
Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Other Specialty Toxicology

Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).

Pharmacology

In Vivo Pharmacology Study the effects of drug candidates in animal models

Pharmacovigilance

GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.
IND/CTA Authoring and Publishing Services IND/CTA authoring and publishing services involve preparing, compiling, and submitting Investigational New Drug (IND) applications or Clinical Trial Applications (CTA) to regulatory authorities, ensuring compliance...
Periodic Safety Update Reports (PSURs) / Periodic Benefit-Risk Evaluation Reports (PBRERs) Preparation of safety reports to report adverse events that occurred during a specified time period. Evaluate if safety profile of treatment has changed since last report.

Product Development

Environmentally/Eco Friendly Componentry design services for environmental/eco-friendly products
Oral Care - Manufacturing Manufacturing services for oral care products
Oral Care Products - Formulation Formulation services for oral care products.
Over-The-Counter (Other) - Manufacturing Other manufacturing services for Over-The-Counter (OTC) products
Over-The-Counter/OTC (Other) - Formulation Other formulations for Over-The-Counter (OTC) products
Specialty (Other) - Formulation Other formulations for specialty products in personal care

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Specialty (Other) - Manufacturing Other manufacturing services for specialty products in personal care

Protein Sciences

Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
Antimicrobial Peptide Synthesis Make a peptide with anti-microbial activities.
Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.

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Carbohydrate Isolation Obtain pure monosaccharides, pure polysaccharides or related derivatives from samples.
Cytokines Find recombinant cytokines or cytokine assays.
ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
Fluorescence Polarization Investigate receptor-ligand interactions, protein-DNA interactions, proteolysis and membrane fluidity.
Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
FRET/BRET Detect the location of proteins in living cells and their ability to interact with other proteins.
Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
Integrated Protein Production Package Process an entire Protein Production Pipeline Project including: Gene/Oligo Synthesis, Cloning/Subcloning, Protein Expression, Protein Purification, Protein Analysis, and Protein Products from our bundle of suppliers
Integrated Proteomics Package Process an entire Proteomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers
Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Lentivirus Production Develop lentiviruses and production protocols.
Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
Native Protein Purification Purify native proteins from sources such as tissue & serum.
Neoantigen Development Develop neoantigens for oncological therapeutics for vaccine development.
NMR Determine molecular and protein structure, and validate sample integrity.
Peptide Derivatives Acquire chemicals that are peptide derivatives.
Peptide Discovery Identifying and developing new peptides.
Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
Phage Display Use in vitro screening method to identify protein binding partners.
Phosphorylation Analysis Identify phosphorylation sites in target proteins.
Protein Binding Determine drug-protein binding interactions
Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
Protein Engineering Alter the features or properties of a protein for a specific purpose.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Identification Uncover or confirm the identity of a protein.
Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Protein mapping Interrogate the entire sequence of a protein.
Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
Protein Products Find native and recombinant proteins and peptides.
Protein Purification Isolate native or recombinant proteins from a sample.
Protein Reagents Request information or a price quote for Protein Reagents services
Protein Sequencing Determine the amino acid sequence of protein or peptide.
Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.
Quantitative MS Quantify small and large molecules in the pg/ml range
Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.
Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.
Solution Phase Peptide Synthesis (SPS) Solution-phase peptide synthesis (SPS) is the classical, liquid-medium method for creating peptides by coupling amino acids
Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
Virus Production Produce high titer viruses, viral expression vectors and vaccines.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.

Raw Materials

Antimicrobial Active Ingredients Acquire antimicrobial active ingredients for making consumer healthcare products.
Drug Actives (Other) Formulate and develop products that contain active ingredients such as salicylic acid, benzoyl peroxide, azelaic acid, tacrolimus, and pimecrolimus.
Ophthalmic Active Ingredients Acquire ophthalmic active ingredients for making vision care products.
Oral Discomfort Relief Active Ingredients Acquire oral discomfort relief active ingredients for making consumer healthcare products.
Pediculicide Active Ingredients Acquire pediculicide active ingredients for making consumer healthcare products.
Sedative Active Ingredients Acquire sedative active ingredients for making over-the-counter medicines.

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Stimulant Active Ingredients Acquire stimulant active ingredients for making over-the-counter medicines.
Topical Analgesic Active Ingredients Acquire topical analgesic active ingredients for making consumer healthcare products.
Weight Control Active Ingredients Acquire weight control active ingredients active ingredients for making over-the-counter medicines.

REACH Services

OECD 410: Repeated Dose Dermal Toxicity: 21/28-day Study This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance.
OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...

Real World Evidence & Data

RWE/HEOR Data Analysis Analysis that helps you make sense of your RWE/HEOR data

Regulatory Affairs

Life Cycle Management Plan and strategy of the data collection and information throughout the different phases of product development (portfolio assessment, pre-clinical trials, clinical trials, pre-authorization, post-authorization, and RWE)
Period Benefit Risk Evaluation Report (PBRER) Preparation of safety reports to report adverse events that occurred during a specified time period. Evaluate if safety profile of treatment has changed since last report
Periodic Safety Update Report (PSUR) Preparation of safety reports to report adverse events that occurred during a specified time period. Evaluate if safety profile of treatment has changed since last report
Post Authorization Efficacy Study (PAES) Answer uncertainties in efficacy of treatment, and improve understanding of treatment and the benefit-risk profile. These studies are specifically asked for by European Medicines Agency (EMA) to continually grant...
Post Authorization Safety Study (PASS) Evaluate the safety, benefit-risk profile, and risk management of a treatment. These studies are specifically asked for by European Medicines Agency (EMA) and they can be mandatory or voluntary.
Regulatory Submission Documents Request services related to the submission and writing of New Drug Applications (NDA), Investigational New Drugs (INDs), and Investigator Brochures (IB) to the FDA and other regulatory bodies.

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Risk Benefit Assessment Determine ratio of treatment risk to the potential benefits.

Regulatory Consulting

Toxicology Data Review Identify relevant toxicological endpoints for “No Observed (Adverse) Effect Level” (NO(A)EL) or “Lowest Observed (Adverse) Effect Level” (LO(A)EL).

Safety Pharmacology

Abuse and Dependence Liability Testing Determine the abuse or dependence potential of a therapeutic.
Abuse Liability Determine the dependence potential of a therapeutic.
CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
Conditioned Place Preference or Aversion Study - Mouse Conduct a study to establish the aversion or conditioned place preference and determine the motivational effect of your compound in mice.
Dependence Potential Study - Other Species Conduct a study to determine the dependence potential of your compound in other species.
Dependence Potential Study - Rat Conduct a study to determine the dependence potential of your compound in rats.

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Drug Discrimination Study - Other Species Conduct a study to investigate the length of psychoactive effects of your compound in other species and conduct dose range finding for further studies.
Drug Discrimination Study - Rat Conduct a study to investigate the length of psychoactive effects of your compound in rats and conduct dose range finding for further studies.
Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
Implanted Telemetry Study - Dog / Canine Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in dogs/canines.
Implanted Telemetry Study - Monkey / Non-human Primate Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in monkeys/non-human primates.
Implanted Telemetry Study - Other Species Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in other species.
Implanted Telemetry Study - Rat Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in rats.
Locomotor Activity Assessment Study - Rat Conduct a study to determine the psychostimulant or sedative activity or your compound in rats.
Microelectrode Array Neurotoxicity Assays Use microelectrode array to measure neurotoxicity-related activities.
Neurotoxicity Study Study of the adverse effects of a substance on the brain or peripheral nervous system.
Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Repeat Dose Neurotoxicity Study - Other Species Conduct a repeat dose study in other species to determine the neurotoxicity of your compound.
Repeat Dose Neurotoxicity Study - Rat Conduct a repeat dose study in rats to determine the neurotoxicity of your compound.
Respiratory Toxicology Assess difficulty breathing, altered respiration, blood gas changes and blood pH issues due to adverse reactions.
Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Safety Pharmacology Latin Square Study - Dog / Canine Conduct a safety pharmacology study with a Latin square design in dogs/canines.
Safety Pharmacology Latin Square Study - Monkey / Non-human Primate Conduct a safety pharmacology study with a Latin square design in monkeys/non-human primates.
Safety Pharmacology Latin Square Study - Other Species Conduct a safety pharmacology study with a Latin square design in other species.
Safety Pharmacology Study with Functional Observational Batteries (FOBs) - Other Species Conduct a safety pharmacology study with functional oberservational batteries in other species.
Seizure Liability Study - Other Species Conduct a study to determine the seizure risk of your compound in other species.
Seizure Liability Study - Rat Conduct a study to determine the seizure risk of your compound in rats.
Self Administration Study - Other Species Conduct a study to investigate the potential addictive characteristics of your compound in other species.
Self Administration Study - Rat Conduct a study to investigate the potential addictive characteristics of your compound in rats.
Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.
Telemetry Use implantable or external devices to study physiological parameters in model organisms
Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.

Scientific Data Services

Automated Image Analysis Automated Image Analysis
Bayesian Statistics Extract information from data sets that are subject to error or noise to see unobserved possibilities.
Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
Data and Text Mining Derive structured data from free text in order to become accessible for data-mining algorithms.
Data Curation Organize and integrate data collected from various sources to ease data discovery and retrieval.

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Database Integration Convert bioinformatics results from multiple data sources (DSs) into a single operational format.
Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
Epigenomics Data Analysis Quantify and analyze DNA methylation and/or DNA binding protein data sets.
Large Language Models Use of Large Language models in target discovery, clinical trial design and development, analysis of clinical trial data and regulatory submissions. Services are tailored to the problem, specific context of biopharma.
Machine Learning/ AI Predict and model an outcome (e.g. disease progression) based on input variables (i.e. features.)
Marker Analyses Identify associations between genetic markers and traits of interest to determine markers responsible for human diseases.
Metabolomics Data Analysis Use metabolites to identify any potential biomarkers or novel therapeutic targets that may play a role in the mechanisms responsible for the progression of a disease.
Metagenomics Data Analysis Deconvolute the genetic content of genomes contained in environmental samples by utilizing whole genome sequencing techniques to provide insight into microbial communities and host phenotypes.
Microbiome Data Analysis Determine the population composition of a microbial community and analyze its contribution to human or animal health.
Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
Molecular Phylogenetics Analyze hereditary molecular differences in genomic sequences to compare genomes.
Mutation Data Profiling Guide treatment decisions in cancer based on the identification of genomic mutations .
NGS: Next Generation Sequencing Data Analysis Use software to interpret data created by RNA-Seq, DNA-Seq, ChIP-Seq and DNA methylation experiments.
Omics Informatics Consulting Services for the analysis of large-scale molecular data sets.
Ontology Mapping Assign given ontologies to source data. 
Pharmaco-genomics Genetic polymorphism contribution to inter-individual variability in drugs' responses and/or adverse events.
Scientific Data Visualization Exploration and reporting of data by means of graphs and plots.
Scientific Pipeline Implementation Design, develop and deploy data analyses workflows.
Small RNA Gene Expression Quantify and analyze miRNA, piRNA, siRNA as well as other small nuclear RNAs from small-RNA-seq raw input data sets.
System Development Plan, create and deploy an information system.
Systems Biomedicine Analyze complex interactions in biological systems with interdisciplinary scientific teams.
Systems Network Analysis Analyze and visualize molecular pathways including gene regulatory, protein-protein and drug-target networks.
Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.
WBA Technologies Request information or a price quote for WBA Technologies services. (global industry bodies driving the adoption of next-gen Wi-Fi, 5G, 6G, IoT, and OpenRoaming)

Specialty Dosing Routes

Intra-Articular Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered directly to the joint.
Intrathecal/Intraspinal Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the intrathecal space.
Repeat Dose Intranasal Study - Dog / Canine Conduct a repeat dose intranasal study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intranasal Study - Monkey / Non-human Primate Conduct a repeat dose intranasal study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intranasal Study - Mouse Conduct a repeat dose intranasal study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intranasal Study - Other Species Conduct a repeat dose intranasal study in other species to determine the toxicity and toxicokinetic behavior of your compound.

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Repeat Dose Intranasal Study - Rat Conduct a repeat dose intranasal study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Dog / Canine Conduct a repeat dose intravenous infusion study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Monkey / Non-human Primate Conduct a repeat dose intravenous infusion study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Other Species Conduct a repeat dose intravenous infusion study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Rats Conduct a repeat dose intravenous infusion study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Single Dose Acute Intranasal Study - Dog / Canine Conduct a single dose intranasal study in dogs/canines to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intranasal Study - Mouse Conduct a single dose intranasal study in mice to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intranasal Study - Other Species Conduct a single dose intranasal study in other species to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intranasal Study - Rat Conduct a single dose intranasal study in rats to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Dog / Canine Conduct a single dose intravenous infusion study in dogs/canines to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Monkey / Non-human Primate Conduct a single dose intravenous infusion study in monkeys/non-human primates to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Other Species Conduct a single dose intravenous infusion study in other species to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Rats Conduct a single dose intravenous infusion study in rats to determine the toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a topical ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct a topical ocular toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Mouse Conduct a topical ocular toxicity study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct a topical ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct a topical ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
Topical Ocular Toxicity and/or Toxicokinetic Study - Rat Conduct a topical ocular toxicity study in rats to determine the toxicity and toxicokinetic behavior of your compound.

Testing Services

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
ASTM E2315: Time-Kill Procedure (Antimicrobial Testing Study) Assessment of Antimicrobial Activity Using a Time-Kill Procedure
Bacterial Identification Testing Use biochemical and molecular methods to identify unknown microorganisms.
Bacterial Reverse Mutation Assay Test whether a cosmetic product or ingredient causes DNA mutations in bacteria.
Characteristic Testing Characterization of physical and chemical properties of raw materials
CLSI M26-A: Minimum Bactericidal Concentration (MBC) Determine the lowest concentration of an antimicrobial agent that is lethal to the target bacteria in vitro.

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Elevated Temperature Stability Determine the stability of a product at elevated temperature.
Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
Microbiological Sterility Testing Test the presence of viable microorganisms.
Non-Acnegenicity & Non-Comedogenicity Test Test whether a cosmetic product is likely to cause acne and comedones (pimples).
Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
PAO Stability Trial Assess the stability of a consumer product under certain storage conditions.
Phototoxicity and Photosensitization Screening Screen a consumer healthcare product for irritancy and/or allergy potential following exposure to UV light.
Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.

Other services

IND Writing Receive assistance with materials for an IND application.
NDA Writing Receive assistance in the NDA application process.
New Request  
Rare Diseases Recruitment of volunteers or study participants who have a rare disease, or specifically in the "U.S.when a chronic and enervating condition afflicts fewer than 200,000 people combined, and in the EU, when it affects...
Site Management Organizations Site Management Organization (SMO) is an organization that provides clinical trial related services to a contract research organization (CRO), a pharmaceutical company, a biotechnology company, a medical device...
Transcriptome In Vivo Analysis (TIVA) Use TIVA for photo-activated capture of mRNA from a single cell or sub-cellular region.

Service areas:

Biology Chemistry DMPK Pharmacology

Germany Hamburg, Gottingen, Neuried 4 sites
United Kingdom Abingdon 3 sites
France Lyon, Toulouse 2 sites
Italy Verona 1 site
United States Princeton 1 site

You can email your enquiries directly to Evotec if you need to at: [removed] You can also request further information on Evotec's drug discovery services and partnering information via our website: Click here Evotec is a drug discovery alliance and development partnership company focused on rapidly progressing innovative product approaches with leading pharmaceutical and biotechnology companies. We operate worldwide providing the highest quality stand-alone and integrated drug discovery solutions, covering all activities from target-to-clinic. The Company has established a unique position...

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You can email your enquiries directly to Evotec if you need to at: [removed]

You can also request further information on Evotec's drug discovery services and partnering information via our website: Click here

Evotec is a drug discovery alliance and development partnership company focused on rapidly progressing innovative product approaches with leading pharmaceutical and biotechnology companies. We operate worldwide providing the highest quality stand-alone and integrated drug discovery solutions, covering all activities from target-to-clinic. The Company has established a unique position by assembling top-class scientific experts and integrating state-of-the-art technologies as well as substantial experience and expertise in key therapeutic areas including neuroscience, pain, metabolic diseases as well as oncology and inflammation.

Evotec has long-term discovery alliances with partners including Bayer, Boehringer Ingelheim, CHDI, Genentech, Janssen Pharmaceuticals, MedImmune/AstraZeneca and Ono Pharmaceutical. In addition, the Company has existing development partnerships and product candidates both in clinical and pre-clinical development. These include partnerships with Boehringer Ingelheim, MedImmune and Andromeda (Teva) in the field of diabetes, with Janssen Pharmaceuticals in the field of depression and with Roche in the field of Alzheimer’s disease.

Evotec is built on integrated drug discovery know-how of more than 15 years and is a leading player in the drug discovery field. The Company’s headquarters are located in Hamburg, Germany. Additional major operations are based in Abingdon,Manchester, UK, Göttingen, Munich, Germany, San Francisco and Branford, USA. Evotec has more than 600 employees worldwide.

EVOTEC’S CAPABILITIES INCLUDE THE FOLLOWING:

Integrated Services

Target Identification and Validation

High-throughput Screening

High-Content Screening

Structure-Based Drug Design (SBBD)

Chemistry & Medicinal Chemistry

Structural Biology

ADMET

In vitro pharmacology

In vivo pharmacology / DMPK

Antibody Identification

Proteomics

Compound Profiling and High-throughput ADME

Compound Management

Cell and protein production

Ion Channels Drug Discovery

For an overview of our drug discovery services, please Click here

To view or download Evotec's poster presentations, publications and white papers, please Click here

Professional associations: BIOCOM, DCAT, Society of Laboratory Automation and Screening (SLAS)
Website: www.evotec.com

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