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Fundació Institut Català d´Investigació Química - ICIQ

Fundació Institut Català d´Investigació Química - ICIQ is listed as an academic core research supplier in the Scientist.com network, with 5 sites in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 5

Countries 1

Logo Centres de Recerca de Catalunya, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.

Type of company: Academic core

Agricultural Sciences Compliance and Quality Control Measures

Residue Chemistry Pesticide residue and tolerance testing.

Agricultural Sciences Research & Development

Agrochemical Identification Product identification and composition of pesticides; which includes fungicides, insecticide, herbicides and nematicides analysis.
Chemical and Physical Determination of chemical and physical properties of pesticide product.
Synthetic Fertilizers Determination of heavy metals and other toxic compounds in addition to composition.

Bioimaging

Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
Micro Electron Diffraction (MicroED) Use electron diffraction to determine the structure of biological materials.
Scanning Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.

Chemical and Compound Analysis

Adsorption/Desorption Studies Obtain data on groundwater risk assessment.
API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Chemical Stability Measure the stability of small molecules in solution.
Chiral Separation Purify therapeutically active isomers of drug candidates.
Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
Compound Integrity Analyze the identity and purity of small molecule drug candidates.

Show all 38 in Chemical and Compound Analysis 32 more

Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
Electron Diffraction Measurement (microED) Use electron diffraction patterns to characterize the crystallographic properties of a sample.
Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
Ion Exchange Chromatography Separate and detect analytes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
Photostability Measure drug degradation rates after exposure to various light sources.
Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
Process Residual Impurities Detection Measure trace levels of impurities.
Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
Scanning and Transmission Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Small Angle X-Ray Scattering Obtain low-resolution structures of biopolymers in solution using an x-ray beam.
Solid State Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solid samples.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Static Light Scattering Use scattered light intensity to determine the average molecular weight of biopolymers.
Structural Chemistry Examine the relationship between protein structure and function.
Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.

Show all 93 services 80 more

Chemical and Compound Testing

Product Testing Ensure product quality standards are met.

Chemistry, Manufacturing and Controls (CMC)

Advanced intermediates Sourcing advanced intermediates
Analytical Development and Validation Request services related to Analytical Development and Validation
API and Drug Product Stability Testing API and Drug Product Stability Testing.
API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.

Show all 16 in Chemistry, Manufacturing and Controls (CMC) 10 more

Crystallization studies Crystallization studies
Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
Milling, grinding, spray-drying Milling, grinding, spray-drying
Polymorph Screening Screen for unwanted API forms resulting from the drug formulation process.
Raw Materials & Ingredients Purchase raw materials, ingredients, or chemicals for personal care, cosmetic, consumer health, and beauty products and substances.
Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.

Discovery Chemistry

Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
Certified Standards Find certified standards for assays, tests and services.
Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
Compound Purchase Buy compounds, building blocks or compound libraries.
Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.

Show all 21 in Discovery Chemistry 15 more

Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
Leachable and extractable testing Leachable and extractable testing
Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.

Drug Development

Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
Chemoinformatics Consulting The use of computer and informational techniques applied to a range of problems in the field of chemistry.
Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.

In Vitro ADME

Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.

Lab Supplies, Facilities, and Equipment

Lab Equipment Mechanical Design Obtain custom laboratory equipment modification and/or production.

Medical Communications

Medical Publications Make clear and accurate presentations of scientific and technical data.

Protein Sciences

X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.

Testing Services

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
Elevated Temperature Stability Determine the stability of a product at elevated temperature.

Service areas:

Chemistry

Spain Tarragona 5 sites

Crysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates.

Crysforma has developed its own crystallization screening methodology based on the combination of several crystallization procedures.

Website: www.iciq.org

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