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Trenzyme
Trenzyme is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Research & Development
- DNA/Protein analysis Analyze DNA and proteins for allergens, pathogens and species identification.
Antibodies
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Show all 10 in Antibodies
- Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
- Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
- SARS-CoV-2 (COVID-19) Protein and Antigen Search for available SARS-CoV-2 proteins and antigens
- Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.
Bioimaging
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
- Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.
Biomarkers
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Show all 12 in Biomarkers
- Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
- Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Show all 112 services
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Line Authentication Verify the identity and purity of an experimental cell line or industrial culture.
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
Show all 18 in Cell Culture and Characterization
- Cell Line Construction Create new recombinant cell lines to exact specifications.
- Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Chromosomal Characterization Establish karyotype/chromosome profile by cytogenetic analysis of cell preparation.
- Custom htert immortalization Custom human telomerase immortalized primary cells
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
- Insect Tissue Culture Grow insect cells.
- Lipofection Transfection of DNA/RNA using lipofection reagents to create lipoplexes.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
- Stem Cell Methodologies Study Stem Cell characteristics.
- Yeast Cell Culture Grow yeast strains or species.
Chemical and Compound Analysis
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Chemistry, Manufacturing and Controls (CMC)
- Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Discovery Chemistry
- Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
DNA & RNA
- cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
- DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
- DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
- Genomic DNA cloning Clone and propagate genomic DNA inserts of 5-50kb.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
Show all 7 in DNA & RNA
- qPCR Analysis Measure the accumulation of PCR products in real time.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
- Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
Human Biological Samples
- Cell Line and Cellular Services Promotion for Cells and Cell lines
- Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
In Vitro ADME
- Cell Fractionation Isolate organelles and subcellular components.
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Show all 15 in In Vitro Assays
- Cell Proliferation Measure cell number, cell viability and cell division.
- Glucose Release Assay Determine free glucose levels in biological samples.
- Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.
- In Vitro Human Cell Assays Request in vitro human cells for assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
- Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Protein/Enzyme Targets For requesting Protein/Enzyme Targets
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Protein Sciences
- Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
- Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- Cytokines Find recombinant cytokines or cytokine assays.
- Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
Show all 26 in Protein Sciences
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
- Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
- Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- Native Protein Purification Purify native proteins from sources such as tissue & serum.
- Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
- Protein Binding Determine drug-protein binding interactions
- Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Identification Uncover or confirm the identity of a protein.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Products Find native and recombinant proteins and peptides.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.
- Virus Production Produce high titer viruses, viral expression vectors and vaccines.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
- Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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Germany 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Highly modular services We at Trenzyme offer highly individualized and modular services, mainly in three different areas: - cell line development - recombinant protein production - molecular biology Cell line development on the fast track Using our ExoIN technology and the newly developed FreezeFect cells, we are able to generate the stable mammalian cell line you are looking for in only 30 business days. Perfect for assay development or protein production. Recombinant expression in different procaryotic and eucaryotic host systems We will provide the protein you are looking for. Choose our...
Show the full description
Highly modular services
We at Trenzyme offer highly individualized and modular services, mainly in three different areas:
- cell line development
- recombinant protein production
- molecular biology
Cell line development on the fast track
Using our ExoIN technology and the newly developed FreezeFect cells, we are able to generate the stable mammalian cell line you are looking for in only 30 business days. Perfect for assay development or protein production.
Recombinant expression in different procaryotic and eucaryotic host systems
We will provide the protein you are looking for. Choose our fast and all-inclusive package "Fixed-price protein manufacturing" or our highly individual "cross organism expression platform" to ensure your success.
Molecular biology services according to your needs
As combination with the abovementioned services or as standalone package, we offer gene synthesis, custom cloning and vector construction, mutagenesis and plasmid DNA purification.
Regardless of whether your project will be covered by only one of the areas or by different - we always have one goal:
Accelerating your innovation!
- Website
- www.trenzyme.com
Work with Trenzyme on Scientist.com
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