siTOOLs Biotech GmbH

siTOOLs Biotech GmbH is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.

CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
De Novo Transcriptome Sequencing Identify new genes without the need for a reference genome sequence.
DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.

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qPCR Analysis Measure the accumulation of PCR products in real time.
RNA Extraction Isolate total RNA or mRNA from cells or tissues
RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNAi Pathway Analysis Use high-throughput RNAi genetic screens to elucidate relevant signaling pathways.
shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
siPOOL Technology Gene silencing tool with exceptional targeting specificity based on high complexity siRNA pooling and detailed bioinformatics-based design.
siRNA Synthesis Produce high quality siRNAs for gene silencing studies.
Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.

Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Proliferation Measure cell number, cell viability and cell division.
High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
HTS Assay Development Develop assays to use in high throughput screening.

High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.

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