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Guilford Street Labs (GSL)

Guilford Street Labs (GSL) is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
  • Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
  • Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
  • Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
Show all 15 in Biomarkers 9 more
  • Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
  • Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
  • Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
  • Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
  • Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.

Chemical and Compound Analysis

  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.

Clinical Consulting

  • Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

Data Science/Bioinformatics

  • Clinical Biomarker Analysis An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
  • Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.

Discovery Chemistry

  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
  • Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Show all 32 services 19 more

In Vitro ADME

  • Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.

Protein Sciences

  • Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
  • Integrated Proteomics Package Process an entire Proteomics Pipeline Project including: Sample Preparation, Target Enrichment, NGS Instrumentation, and Data Analysis from our Bundle of Suppliers
  • LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
  • Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
  • Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
  • Qualitative MS Perform direct identification of molecules based on mass-to-charge ratio and fragmentation patterns.
Show all 8 in Protein Sciences 2 more
  • Quantitative MS Quantify small and large molecules in the pg/ml range
  • SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.

Scientific Data Services

  • Metabolomics Data Analysis Use metabolites to identify any potential biomarkers or novel therapeutic targets that may play a role in the mechanisms responsible for the progression of a disease.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Liverpool, London 2 sites

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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