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Taconic Biosciences
Taconic Biosciences is listed as a large business research supplier in the Scientist.com network, with 10 sites in 3 countries and 3 service areas.
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Sites
10
Countries
3
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
Biomarkers
- Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Disease Models
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Auto-immune Hepatitis Models Measure therapeutic endpoints in animal models with auto-immune hepatitis.
- Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
- Cyp2f2 Knockout Mouse Study Cyp2f2-mediated lung metabolism.
Show all 22 in Disease Models
- Fecal Microbiota Transplantation (FMT) - Mouse Use germ-free mice to evaluate the properties of complex or defined gut microbiota following fecal microbiota transplantation (FMT). Axenic (germ-free) mice transplanted with donor microbiota can be utilized to assess...
- Hematopoiesis Models Measure therapeutic endpoints in animal models of hematopoiesis.
- In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
- Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
- LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
- Malaria Models Measure therapeutic endpoints in animal models of malaria.
- Multiple Sclerosis Models Measure therapeutic endpoints in animal models of multiple sclerosis.
- Neuropathic Pain Models Measure therapeutic endpoints in animal models of neuropathic pain.
- Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
- Schizophrenia Models Measure therapeutic endpoints in animal models of schizophrenia.
- Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
- Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.
DNA & RNA
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
- SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Show all 60 services
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
In Vitro ADME
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Glucose Release Assay Determine free glucose levels in biological samples.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- C57BL/6 Immunocompetent Mouse Use a single animal species to create one or more disease models for metastatic cancer.
- Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
- Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
- Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
- NMRI Mouse Use a single animal species to create one or more disease models for cachexia and hemophilia.
Show all 13 in Model Development
- Pseudopregnant CD1 Mouse Use a single animal species to create gene-modified mouse models.
- SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
- SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
- Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
- Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
- Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Oncology Models
- Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
- Animal Hypoxia Models Measure therapeutic endpoints in hypoxic animal models.
- Leukemia Xenograft Measure therapeutic endpoints in leukemia models of cancer.
- Oncology Xenografts Xenografts derived from oncological samples.
Pharmacology
- In Vivo Pharmacology Study the effects of drug candidates in animal models
Other services
- huNOG-EXL Model Understand how human immune response impacts disease in immune system engrafted mice.
- New Request
Service areas:
Biology
DMPK
Pharmacology
Where it operates
Sites by country, with the cities in each.
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United States 4 sites
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Denmark 3 sites
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Germany 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
As the industry leader for more than 60 years, Taconic accelerates drug discovery by providing fast, convenient access to a full suite of more than 4,000 off-the-shelf in vivo mouse and rat models, as well as models custom designed to your research needs. Taconic provides study-ready cohorts, including tissue or genetically humanized models, supported by reliable data that can advance your early development work. Our scientific expertise, innovative technology and breeding services, enables you to confidently partner with Taconic for your entire spectrum of in vivo resource needs. Taconic's...
Show the full description
As the industry leader for more than 60 years, Taconic accelerates drug discovery by providing fast, convenient access to a full suite of more than 4,000 off-the-shelf in vivo mouse and rat models, as well as models custom designed to your research needs. Taconic provides study-ready cohorts, including tissue or genetically humanized models, supported by reliable data that can advance your early development work. Our scientific expertise, innovative technology and breeding services, enables you to confidently partner with Taconic for your entire spectrum of in vivo resource needs.
Taconic's industry leading portfolio of solutions includes:
- Custom model generation services that provide easy access to precisely defined models to suit your specific research project, using advanced technologies such as pronuclear microinjection, targeted gene mutation and targeted gene replacement
- Extensive animal model repositories, including the Taconic Transgenic Model™ portfolio of in-licensed transgenics, a Knockout Repository of 4,000+ mouse lines, and the Emerging Models portfolio of investigator-sponsored models
- tADMET™ models that yield far greater predictability of ADMET in man and improve the safety assessment of drug candidates by knocking out key murine genes or replacing them with their human counterparts
- Light-producing transgenic models that use novel bioluminescent technology to greatly enhance the study of inflammation, oncology, metabolic disease, and drug metabolism/toxicology
- Custom breeding solutions customized to your specific needs and designed to help you achieve your research objectives, by providing the right models quickly, cost-effectively and in the volume your research demands
- Surgical services including cannulations and implants, customized procedures, and the creation of surgical models of disease, all performed by highly trained in-house surgical technicians
- Testing services that use the most advanced technology to determine the precise genetic characterization of your model and monitor animal health status
- Health monitoring services through our proprietary Taconic International Health Monitoring System™, which meets or exceeds the animal health guidelines of virtually all research institutions
- Website
- www.taconic.com
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