Trudeau Institute Flow Cytometry Core

TICRO works closely with clients to create the comprehensive study design, management, and execution strategies needed to achieve project objectives with exceptional efficiency. Our highly skilled experts are able to anticipate the challenges of infectious disease research and offer clients creative and personalized project design, while maintaining consistent performance with quality-focused SOPs throughout project execution. Our risk assessment experience, project management insights, established processes, and specialized infrastructure enable us to provide clients with high-quality, cost-effective research project design and execution.

Immunophenotyping using models of infection and host defense, including murine models of influenza, tuberculosis and pneumonia
Immunogenicity and immunotoxicology evaluation of candidate therapeutics, vaccines and adjuvants
Preclinical efficacy testing of antibacterials, antivirals and vaccines with microbiological and clinical endpoints
KEY CAPABILITIES

Mouse models of infection with a broad range of pathogens, including many that target the respiratory tract
Animal facilities and technical services, including bio-safety level 2 and 3 suites with select agent capabilities, surgery, rederivation, cryopreservation, breeding and aging
Flow cytometry services, including design and execution of multi-parameter phenotyping of low frequency cells and isolation of specific cell populations from infected samples
Microscopy and imaging services including advanced histology, immunohistochemistry, immunofluorescence, and imaging
Molecular biology services, including investigations of the impact of candidate therapeutics, infectious disease, vaccines, and adjuvants on immune cell function at the molecular and gene expression levels