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Jiangxi Zvast Biotechnology Co., Ltd.

Jiangxi Zvast Biotechnology Co., Ltd. is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.

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Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Antibodies

  • Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.

Biomarkers

  • Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
  • Osteoclasts Measure osteoclast activity and bone resorption in human, mouse or rat assays.

Cell Culture and Characterization

  • 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
  • Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
  • Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
  • Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
  • Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.

Clinical Trials

  • Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.

Data Science/Bioinformatics

  • Translational Data Science and Modeling A process that helps make sense of your translational data

Developmental and Reproductive Toxicology (DART)

  • In Vitro Alternative Model for Assessing Reproductive Toxicity Laboratory-based methods used to evaluate the potential harmful effects of substances on reproduction without using live animals.

Discovery Chemistry

  • Discovery Molecular Modeling and Simulation Analytics Computational methods to model and study the behavior of molecules, from small chemical systems to large biological molecules.
  • Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
Show all 214 services 201 more

Disease Models

  • Acute Kidney Failure Models Measure therapeutic endpoints in animal models of acute kidney failure.
  • Acute Liver Failure Models Measure therapeutic endpoints in animal models of acute liver failure.
  • Acute Lung Injury Models Measure therapeutic endpoints in animal models of acute lung injury.
  • Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
  • Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
  • Auto-immune Hepatitis Models Measure therapeutic endpoints in animal models with auto-immune hepatitis.
Show all 104 in Disease Models 98 more
  • Autoimmune Models Measure therapeutic endpoints in animal models with autoimmune disorders.
  • Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
  • Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
  • Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
  • Bone Models Measure therapeutic endpoints in animal models of bone disorders.
  • Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
  • Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
  • Cartilage Repair Models Measure therapeutic endpoints in animal models of cartilage repair.
  • Cataract Models Measure therapeutic endpoints in animal models of cataracts.
  • Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
  • Cognition Models Measure therapeutic endpoints in animal models of cognition.
  • Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
  • Cough Models Test the therapeutic efficacy of drug candidates in cough models.
  • Critical Care Models Diagnose and manage life-threatening conditions requiring sophisticated organ support and invasive monitoring.
  • Cyp2f2 Knockout Mouse Study Cyp2f2-mediated lung metabolism.
  • Demyelination Models Measure therapeutic endpoints in animal models with demyelination pathology.
  • Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
  • Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
  • Disease Simulation Modeling Disease Simulation Modeling
  • Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
  • Dry Eye Models Measure therapeutic endpoints such as tear induction, TBUT, Schirmer strips (tear volume) and cornea staining.
  • Electroencephalogram EEG Models Record electrical activity along the scalp of animal models or human patients.
  • Emesis Models Measure therapeutic endpoints in animal models of emesis.
  • Endometriosis Models Measure therapeutic endpoints in animal models of endometriosis.
  • Fecal Microbiota Transplantation (FMT) - Mouse Use germ-free mice to evaluate the properties of complex or defined gut microbiota following fecal microbiota transplantation (FMT). Axenic (germ-free) mice transplanted with donor microbiota can be utilized to assess...
  • General Pain Models Measure therapeutic endpoints in animal models of general pain.
  • Hair Growth Models Measure dermal histology, skin thickness, % anagen induction, hair proliferation and other hair growth markers.
  • Hematopoiesis Models Measure therapeutic endpoints in animal models of hematopoiesis.
  • Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
  • Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
  • Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
  • IGA Glomerulonephritis Models Measure therapeutic endpoints in animal models of IgA glomerulonephritis.
  • In Vivo Physiologic Monitoring Monitor and collect data from conscious, freely moving laboratory animals.
  • In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
  • Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
  • Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
  • Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
  • Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
  • Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
  • Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
  • Kidney Transplant Models Measure therapeutic endpoints in kidney transplant models.
  • Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
  • Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
  • LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
  • LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
  • Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
  • Malaria Models Measure therapeutic endpoints in animal models of malaria.
  • Menorrhagia Models Measure therapeutic endpoints in animal models of menorrhagia.
  • Microbiome-Based Skin Disease Technology Modify the skin microbiome and deliver therapeutic proteins to the target.
  • Microdialysis Models Measure the effect of drug candidates on neurotransmission in rat or mouse models.
  • Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
  • Morris Water Maze Investigate spatial learning and memory in rodents.
  • Myelination Models Measure therapeutic endpoints in animal models with induced myelination, remyelination or developmental myelination.
  • Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
  • Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
  • Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
  • Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
  • Obese Primates Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
  • Object Recognition Measure spatial navigation, working memory and cognitive function in animal models.
  • Obstructive Sleep Apnea Rat Study pathologic cardiac changes of obstructive sleep apnea (OSA) in a rat model.
  • Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
  • Olfactory Testing Models Measure therapeutic endpoints in animal models of olfactory function.
  • Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
  • Optogenetics (rodent behavioral testing) Use light to selectively control the molecular events in cells of living organisms.
  • Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
  • Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
  • Osteoporosis Models Measure therapeutic endpoints in animal models of osteoporosis.
  • Otitis Media Models Measure therapeutic endpoints in animal models of otitis media.
  • Otology Models Measure vertigo, tinnitus, otitis media and hearing loss in animal models.
  • OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
  • Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
  • Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
  • Pain Models Test therapeutic efficacy of drug candidate in pain model.
  • Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
  • Pigmented Rabbit Use a single animal species to create one or more disease models for eye cancer.
  • Precision Cut Lung Slices (PCLS) Use a phenotypically accurate model of lung behavior for screening and target validation.
  • Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
  • Receptor Binding Models Measure the binding and distribution of drugs and biologics in animal tissues.
  • Receptor Occupancy Models Determine the effective dose and concentration needed to reach effective levels in a given tissue.
  • Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
  • Schizophrenia Models Measure therapeutic endpoints in animal models of schizophrenia.
  • Sclerosis ALS Models Measure therapeutic endpoints in animal models of sclerosis.
  • SHR/NCrl Rat Use a single animal species to create one or more disease models fior hematopoesis.
  • Skin Graft Models Measure therapeutic endpoints in animal models of skin grafts.
  • Sleep and Circadian Biology Systems to collect and analyze data related to sleep and circadian rhythms
  • Spinal Cord Injury Models Measure therapeutic endpoints in models of spinal cord injury.
  • Stroke Models Measure therapeutic endpoints in animal models of stroke.
  • Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.
  • Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
  • Tinnitus Models Measure therapeutic endpoints in animal models of tinnitus.
  • Tissue Rejection Models Measure therapeutic endpoints in animal models of tissue rejection.
  • Ventricular Tachycardia Models Measure therapeutic endpoints in animal models of ventricular tachycardia.
  • Video Behavior Monitoring Systems to collect continuous video for use in behavioral research
  • Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.
  • Visceral Pain Models Measure therapeutic endpoints in animal models of visceral pain.
  • Weanling Rat Use a single animal species to create one or more disease models for anemia.
  • Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.
  • Xenografts Evaluate drug candidate in tissue graft or organ transplant model.

General in vivo Toxicology

  • Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
  • Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

Human Biological Samples

  • Custom PDX models For requesting Custom PDX models
  • Existing PDX models For requesting Existing PDX models
  • HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
  • Human Biopsy Cell Models Request human biopsy cell models.

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
  • Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
  • Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
  • Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
  • Human Blood Brain Barrier on a Chip (BBBoC) Create a blood–brain barrier multicellular model to test drug delivery to the brain.
  • Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
Show all 12 in In Vitro ADME 6 more
  • Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
  • Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
  • Multidrug Resistance Identify potential causes of drug-drug interactions.
  • Nasal Permeability Test for passive diffusion and active transport in nasal permeability models.
  • Ocular Permeability Measure passive diffusion and active transport of drugs across confluent ocular epithelial cells.
  • Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.

In Vitro Assays

  • Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
  • Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.
  • Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.

In Vitro Pharmacology

  • HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
  • In Vitro Bone Models Measure osteoclast activity and bone formation in human or rat osteoclasts.
  • In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
  • In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
  • In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
  • In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
Show all 11 in In Vitro Pharmacology 5 more
  • In Vitro Fertilization Models Measure oocyte maturation, embryo development in culture and sperm fertilizing ability.
  • In Vitro Hemolysis Assay Evaluate the toxicity of a drug, metabolite or excipient by hemolytic release of hemoglobin in the plasma.
  • In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
  • In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.

In Vitro Toxicology

  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
  • Perfused Heart Examine cardiac contractile strength (inotropic effects), heart rate (chronotropic effects) and vascular effects.

In Vivo ADME

  • Chronic Bile Duct Cannulation (BDC) Study - Dog / Canine Conduct a bile duct cannulation (BDC) study in dogs/canines to support the absorption, distribution, metabolism and excretion profiling of your compound.
  • Chronic Bile Duct Cannulation (BDC) Study - Monkey / Non-human Primate Conduct a bile duct cannulation (BDC) study in monkeys/non-human primates to support the absorption, distribution, metabolism and excretion profiling of your compound.
  • Chronic Bile Duct Cannulation (BDC) Study - Rat Conduct a bile duct cannulation (BDC) study in rats to support the absorption, distribution, metabolism and excretion profiling of your compound.

In Vivo Pharmacokinetics

  • In Vivo Immunogenicity Study An in vivo immunogenicity study evaluates a substance's ability to trigger an immune response within a living organism.
  • In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
  • Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
  • Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Market Access

  • Market Access Materials Find general strategies and methods used to market a pharmaceutical product or device.

Medical/Commercial

  • Health & Pharmacoeconomics Identify, measure and compare the cost-benefit ratio of products and services.

Model Development

  • 3D Blood-Brain Barrier Model Use an in vitro 3D blood–brain barrier model for real-time visualization of cellular and barrier functions.
  • Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
  • Animal Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study animal lung behavior.
  • Custom Model Development Develop a custom disease model.
  • Disease Model Database For sourcing disease models.
  • In Silico PK-PD Modeling Quantitative modeling and simulations correlation of pharmacokinetic and pharmacodynamic endpoints in support of preclinical and clinical development.
Show all 24 in Model Development 18 more
  • Japanese White Rabbit Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
  • Knockin Mice Make targeted insertion of a gene of interest into a specific gene locus to create transgenic mice.
  • Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
  • Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
  • NMRI Mouse Use a single animal species to create one or more disease models for cachexia and hemophilia.
  • Non-Human Primate Models Use a single animal species to create one or more disease models.
  • PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
  • PiggyBac Transgenic Mouse Service Obtain single-copy transgenic embryos with consistent expression of any desired transgene.
  • Pre-clinical Animal Surgery Conduct surgey in animals used as pre-clinical models.
  • Pseudopregnant CD1 Mouse Use a single animal species to create gene-modified mouse models.
  • Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
  • SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
  • SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
  • Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
  • Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
  • Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
  • Transgenic Models Create animal models engineered for use in a specific therapeutic area.
  • Zucker Rat Use a single animal species to create one or more disease models for cachexia.

Oncology Models

  • Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
  • Animal Hypoxia Models Measure therapeutic endpoints in hypoxic animal models.
  • Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
  • Cachexia Models Measure therapeutic endpoints in animal models of cachexia.
  • CAR-T Efficacy In Vivo assessment of CAR-T and CAR-NK efficacy in a humanized mouse
  • Endocrine System Xenograft Xenografts derived from organs and glands of the Endocrine system. This include samples from the Pituitary Gland, Thyroid, and Adrenals.
Show all 21 in Oncology Models 15 more
  • Experimental Metastatic Models Measure therapeutic endpoints in animal models of experimental metastatic cancer.
  • Leukemia PDX Measure therapeutic endpoints in patient-derived xenografts of leukemia.
  • Murine Adenocarcinoma 16 (MAC16) Murine Test for therapeutic efficacy of drug candidates in muscle wasting models.
  • Muscle Wasting Models Measure therapeutic endpoints in animal models of muscle wasting.
  • Nervous System Xenografts Xenografts relating to the Nervous system. This includes samples from the Head, Neck, Brain, and Nerves.
  • Noble Rat Use a single animal species to create one or more disease models for hematopoiesis.
  • Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
  • Oncology Xenografts Xenografts derived from oncological samples.
  • Oral Xenograft Measure therapeutic endpoints in oral cancer models as well as cancer models related to the Pharynx.
  • Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
  • Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
  • Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
  • T11 (Breast Cancer) Measure therapeutic endpoints in animal models of breast cancer.
  • Urinary System Xenografts Xenografts derived from organs of the Urinary system. This includes, but is not limited to, xenografts from the Bladder, Kidney, and Urethra.
  • Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Primary Market Research

  • Simulation Models (e.g., uptake models) Builds dynamic frameworks to simulate adoption, market share, or treatment behavior over time. Supports forecasting and strategic scenario planning.

REACH Services

  • In Vitro REACH Services Perform skin or eye irriation tests, sensitivily and geneotoxicity tests
  • OECD 406: Skin Sensitisation This method provides information on health hazard likely to arise from exposure to test substance via intradermical injection and/or epidermical application.
  • OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...

Scientific Data Services

  • Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.

Testing Services

  • In Vitro Oral Care Product Testing Perform in vitro oral care product testing of dental products to evaluate safety and performance, including assessment for cleaning, brushing, whitening, stain removal, erosion, abrasivity and sensitivity.
  • In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
  • Ocular Irritation Test Use human subjects to determine whether a cosmetic product or ingredient can cause ocular irritation.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • China nanchang 1 site

Source: Scientist.com supplier network (site locations)

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