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Research supplier
Altis Biosystems, Inc.
Altis Biosystems, Inc. is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
- Single Cell DNA Sequencing Examine genetic variations in a single cell.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Discovery Chemistry
- Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
Disease Models
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
DNA & RNA
- Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
- Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
Show all 37 services
In Vitro ADME
- Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
- In Vitro ADME in Vitro ADME services
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- In Vitro Human Cell Assays Request in vitro human cells for assays
Show all 8 in In Vitro Assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
In Vitro Pharmacology
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Toxicology
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
Lab Supplies, Facilities, and Equipment
- Biobanking Store and track biological samples.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Testing Services
- In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Altis Biosystems is a biotechnology company, which has developed a series of stem cell platforms, recreating both the small or large human intestinal epithelium for drug testing and microbiome research. Our primary stem cells proliferate into all of the normal differentiated cells that you would expect to see in the intestinal epithelium in both a planar or crypt/villus format. It is meant to replace Caco-2 cells and animal testing, for compound screening, during preclinical studies.
- Website
- www.altisbiosystems.com
Work with Altis Biosystems, Inc. on Scientist.com
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