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Recipharm
Recipharm is listed as a large business research supplier in the Scientist.com network, with 3 sites in 2 countries and 2 service areas.
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Sites
3
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Large business
Agricultural Sciences Research & Development
- Agrochemical Analytical Method Development Engineer sensitive and selective methods that meet GLP validation requirements to assess different agrochemical properties.
Chemical and Compound Analysis
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Chemical Stability Measure the stability of small molecules in solution.
- Chiral Separation Purify therapeutically active isomers of drug candidates.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Show all 23 in Chemical and Compound Analysis
- Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
- Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NBE RIB 2/5 BA Request information or a price quote for GLP Large Molecule Bioanalysis services and products
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Process Residual Impurities Detection Measure trace levels of impurities.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
- Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Chemistry, Manufacturing and Controls (CMC)
- Advanced intermediates Sourcing advanced intermediates
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
- API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
Show all 26 in Chemistry, Manufacturing and Controls (CMC)
- Bulk Manufacturing Find facilities for large-scale mass production.
- Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Compendial test methods Run Compendial test methods (e.g., KF)
- Crystallization studies Crystallization studies
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug product packaging and labeling Drug product packaging and labelling
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Excipients Acquire synthetic or natural inert components to formulate therapeutic agents.
- Fill and Finish Processing Confirm final product sterility, formulation and packaging in the biopharmaceutical process.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
- ICH-compliant stability testing Perform ICH-compliant stability testing
- Powder Blending Use automatic or semi-automatic powder blending machinery to produce consistent mixes.
- Powder Filling Use manual, automatic or semi-automatic machinery to package a variety of powder and granules.
- Regulatory Starting Materials Sourcing regulatory starting materials (RSM)
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
- Tablet Manufacturing Use automatic or semi-automatic machinery to create various standard and non-standard tablets.
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
- Thermo Scientific iCAP Q ICP-MS Expand your analytical capabilities with this complete trace elemental analysis solution for your high-throughput lab.
Show all 82 services
Discovery Chemistry
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Show all 23 in Discovery Chemistry
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Leachable and extractable testing Leachable and extractable testing
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
- QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
- Radiochemical Synthesis Radiolabel small molecules, peptides, cytotoxics or antibody drug conjugates for DMPK analysis.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Processing, Packaging, & Preservation
- Liquid Blending Use automatic or semi-automatic liquid blending machinery to produce consistent mixes.
Protein Sciences
- Carbohydrate Isolation Protocol Development Design and optimize protocols for carbohydrate isolation.
- Protein Binding Determine drug-protein binding interactions
- Protein Purification Isolate native or recombinant proteins from a sample.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Elevated Temperature Stability Determine the stability of a product at elevated temperature.
- Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
- PAO Stability Trial Assess the stability of a consumer product under certain storage conditions.
Other services
- New Request
Service areas:
Chemistry
DMPK
Where it operates
Sites by country, with the cities in each.
-
Sweden 2 sites
-
India 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
OnTarget Chemistry – established in 2008 under the name of OncoTargeting as a spin-out from the Medicinal chemistry, Combinatorial chemistry and Preclinical analysis departments of Pharmacia (Biovitrum). We offer a variety of highly specialized services within the fields of medicinal chemistry, synthesis, preclinical analysis and GLP bioanalysis both for small molecules and proteins. In 2011 we received an award for showing the greatest business potential in the Uppsala region and in 2013 we have now grown to a staff of 27 chemists. We continue to employ some of the industry’s most...
Show the full description
OnTarget Chemistry – established in 2008 under the name of OncoTargeting as a spin-out from the Medicinal chemistry, Combinatorial chemistry and Preclinical analysis departments of Pharmacia (Biovitrum). We offer a variety of highly specialized services within the fields of medicinal chemistry, synthesis, preclinical analysis and GLP bioanalysis both for small molecules and proteins.
In 2011 we received an award for showing the greatest business potential in the Uppsala region and in 2013 we have now grown to a staff of 27 chemists. We continue to employ some of the industry’s most experienced chemists and run a well-trimmed organization with solid values of service, quality and efficiency.
We have
- Run over 600 projects so far for 70 customers in 10 countries, including the US and China
- A success rate over 99%
- Six projects delivered over the last four years currently in clinical trials
- 95% repeat business
We provide services in:
- Preclinical Services - solubility assays, protein binding, plasma stability, LCMS, mass balance.
- Medicinal Chemistry - structure activity relationship, scaffolds, metabolites, chemical labelling
- Autoradiography - metabolism and tissue distribution, 14C label compounds
- Non-GMP Scale-up Synthesis - kilogram (kg) scale
+Downloads+
OnTarget Chemistry Company Brochure
Preformulation Services for Successful In Vivo Studies
Development of Antibody Drug Conjugates
Whole Body Autoradiography
Radiochemistry Services
- Website
- www.recipharm.com
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