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CHELAB SRL

CHELAB SRL is listed as a large business research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Large business

Agricultural Sciences Research & Development

Chemical and Physical Determination of chemical and physical properties of pesticide product.
Method Development & Validation Engineer sensitive and selective methods that meet GLP validation requirements to access different agrochemical properties

Bioimaging

Mass Spectrometry Imaging Visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses

Chemical and Compound Analysis

Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Atomic Absorption Analysis Measure the elemental composition of a diverse array of samples.
Chemical Stability Measure the stability of small molecules in solution.
Denaturing High Performance Liquid Chromatography Separate mixtures of denatured and reannealed oligos to identify single nucleotide substitutions, deletions and insertions.

Show all 30 in Chemical and Compound Analysis 24 more

Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
Filler Content Analysis Evaluate filler material to optimize product performance and process conditions.
Gas Chromatography Gas chromatography is an analytical technique that separates, identifies, and quantifies compounds in a mixture
Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Impurities in API Risk assessment Create a risk-based control strategy to determine any impurities in Active Pharmaceutical Ingredients (API).
Inductively Coupled Plasma (ICP) Analysis Characterize ultra-small levels of multiple solid analytes simultaneously.
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
Ion Exchange Chromatography Separate and detect analytes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
Photostability Measure drug degradation rates after exposure to various light sources.
Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
Process Residual Impurities Detection Measure trace levels of impurities.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
Viscosity Testing Evaluate the fluid flow properties of liquids for product evaluation and quality control.
X-Ray Fluorescence (XRF) Identify and quantify the elemental composition of solid and liquid samples.

Chemical and Compound Testing

Bacterial Water Analysis Analyzing water samples to identify the bacteria present.
Product Testing Ensure product quality standards are met.
USP <2021> Microbial Enumeration Tests Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.
USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.
USP <85> Bacterial Endotoxin Test Test to detect or quantify bacterial endotoxins that may be present in or on a sample.

Show all 112 services 98 more

Chemistry, Manufacturing and Controls (CMC)

Analytical Development and Validation Request services related to Analytical Development and Validation
API and Drug Product Stability Testing API and Drug Product Stability Testing.
API and drug product storage and release API and drug product storage and release
API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)

Show all 13 in Chemistry, Manufacturing and Controls (CMC) 7 more

Coating Analysis Evaluate the coat properties of pharmaceuticals, polymers and other finished materials.
Compendial test methods Run Compendial test methods (e.g., KF)
Drug product packaging and labeling Drug product packaging and labelling
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
ICH-compliant stability testing Perform ICH-compliant stability testing
Impurities in Drugs Risk Assessment Create a risk-based control strategy to determine any toxic elemental impurities that may be present in human medicines.

Discovery Chemistry

Extractable and Leachable Assessment Quantify potential impurities from container closures & packaging.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Leachable and extractable testing Leachable and extractable testing
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Trace Elemental Analysis Identify organic and inorganic elements in foods and dietary supplements at ppm to sub-ppt levels.
UV and IR Profiling Analyze the integrity of a compound or large biomolecule.

DNA & RNA

Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.

Farm & Livestock Solutions

Animal Feed Analysis Test the content and quality of nutrients and biologically active substances in animal feeds. Some analysis that is conducted on feed include; dry matter, crude ash, ash insoluble in acid (sand), crude protein, crude...
Food Pathogen Testing of Listeria, salmonella, campylab, 0157E coli.

Food Safety & Regulations

Anaerobic Plate Count Determine the total anaerobic bacteria present in a food or contact-surface sample.
E.coli spp. Testing Use molecular, immunological or cultured methods to detect the presence of E.Coli species in samplings from food, water, contact surfaces or another source.
Listeria monocytogenes Tests Assess product samples or the direct contact surfaces for a specific and prevalent Listeria species capable of growth at low temperatures.
Listeria spp. Testing Use molecular, immunological or cultured methods to identify potential growth sites for all species of the Listeria genus.
Pseudomonas aeruginosa Testing Use molecular, immunological or cultured methods to confirm the presence or absence of P.aeruginosa in samples from food, water or processing surfaces.
Pseudomonas spp. Testing Detect the presence and abundance of various cold-tolerant Pseudomonas species that cause or contribute to spoilage in meat, poultry, seafood, dairy or beverages.

Show all 9 in Food Safety & Regulations 3 more

Salmonella spp. Testing Use molecular, immunological or cultured methods to identify the presence of Salmonella species in food or contact-surface samples.
Total Coliform Testing Measure the bacterial content of a sample to assess food safety, efficacy of sanitation methods or handling practices.
Water Activity Determine water activity in consumer healthcare products involving a USP or FCC monograph.

In Vitro ADME

Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.

In Vitro Assays

Assay Development Construct or create new assays or modify existing ones.
Microbiology Study microbes and their role in human health.
Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.

In Vitro Toxicology

Genotoxicity Evaluate potential of a compound to cause mutations and chromosomal aberations

Other Specialty Toxicology

Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety
Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
Raw Materials Testing Verify that raw materials are sterile and not contaminated by mycoplasma, virus or other microorganisms.
Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.
United States Pharmacopeia (USP) Testing Use USP standards to ensure quality of pharmaceuticals, supplements and food ingredients.

Processing, Packaging, & Preservation

Preservation and Antioxidant Testing Ensure the foods or dietary supplements are free of preservatives and antioxidants at a potentially harmful level.

Product Development

Over-The-Counter (Other) - Manufacturing Other manufacturing services for Over-The-Counter (OTC) products

Protein Sciences

LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.

REACH Services

OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
OECD 486: Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo The purpose of the unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo is to identify substances that induce DNA repair after excision and removal of a stretch of DNA containing a region of damage...
OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
Pyrogen Test Find suppliers who offer safety tests to detect fever-inducing substances (pyrogens) in pharmaceutical products, medical devices, and other biological products

Testing Services

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
Bacterial Identification Testing Use biochemical and molecular methods to identify unknown microorganisms.
Bacterial Reverse Mutation Assay Test whether a cosmetic product or ingredient causes DNA mutations in bacteria.
Characteristic Testing Characterization of physical and chemical properties of raw materials
Cosmetic Preservative Efficacy Test Assess the efficacy of a product's preservative system.
Cosmetics Aerobic Plate Count Determine the level of aerobic bacteria present in a cosmetic or personal care product.

Show all 24 in Testing Services 18 more

Cosmetics Anaerobic Plate Count Determine the level of anaerobic bacteria present in a cosmetic or personal care product.
Cosmetics Yeast and Mold Count Determine the presence of fungi in a cosmetic or personal care product.
Elevated Temperature Stability Determine the stability of a product at elevated temperature.
Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
In Vitro Oral Care Product Testing Perform in vitro oral care product testing of dental products to evaluate safety and performance, including assessment for cleaning, brushing, whitening, stain removal, erosion, abrasivity and sensitivity.
ISO 11930: Preservative Test Evaluate the antimicrobial stabilization of a cosmetic product as per ISO 11930.
ISO 16217: Water Resistant Testing Evaluation of sunscreen's water resistance (40 and 80 minute)
Microbiological Sterility Testing Test the presence of viable microorganisms.
OECD 435: Skin Corrosion Test - Membrane Barrier Method Use in vitro models to determine whether a cosmetic product or ingredient can cause skin corrosion.
OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.
OECD 442E: Human Cell Line Activation Test (h-CLAT) In vitro skin sensitization test to predict skin sensitization potency.
OECD TG 492: Ocular Irritation Testing Use in vitro skin models to determine whether a product can cause dermal sensitization (e.g. EpiOcular Eye Irritation Test - EIT)
Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
Raw Material Microbiological Testing Examples of which include Microbial Content using USP <61> and <62> and other standards, LAL Endotoxin, Ames Mutagenicity and Sterility.
Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
USP 51 Cosmetic Preservative Efficacy Test Evaluate the antimicrobial stabilization of a cosmetic product as per USP 51.
USP <61> Microbial Limits Test Determine whether a substance or preparation complies with an established specification for microbiological quality.
USP <62> Microbial Limits Test Determine the presence or absence of specific microorganisms.

Website: www.merieuxnutrisciences.com/pharma-healthcare

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