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Research supplier
ABLE Biosciences
ABLE Biosciences is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
- Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
Show all 11 in Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Chemical and Compound Analysis
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
Show all 35 services
DNA & RNA
- DNA Extraction Extract DNA from an original source.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
Human Biological Samples
- Human Cerebral Spinal Fluid (CSF) Acquire fresh/frozen normal cerebrospinal fluid based on patient demographics and history.
In Vitro ADME
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
In Vitro Assays
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
In Vitro Pharmacology
- Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
- Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- Protein Binding Determine drug-protein binding interactions
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Service areas:
Where it operates
Sites by country, with the cities in each.
-
Italy 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
ABLE Biosciences (Analytical and Biological Laboratories and Expertise in Biosciences) offers quantitative and qualitative analysis of small molecules, peptides, proteins, including protein biomarkers.
- Website
- www.ablebiosciences.com
Work with ABLE Biosciences on Scientist.com
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